Clinical trials: BMD
Osteoporosis
Comparison of Teriparatide With Alendronate for Treating Glucocorticoid-Induced Osteoporosis
Osteoporosis is a condition in which the amount of bone is reduced, the bones are weak, and there is an increased risk for fractures.
- Trial name
- NCT00051558
- Testing
- Teriparatide, Alendronate Sodium
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 428 people
- Sponsor
- Eli Lilly and Company
Duchenne Muscular Dystrophy
Six Month Study of Gentamicin in Duchenne Muscular Dystrophy With Stop Codons
The purpose of this study is to determine the safety of giving intravenous (IV) gentamicin to boys with Duchenne muscular dystrophy who have stop codon mutations.
- Trial name
- NCT00451074
- Testing
- Gentamicin infusions twice a week for six months
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Osteopenia, Osteoporosis
Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density
This study is designed to provide information on the safety, tolerability, pharmacokinetics (PK) and bone biomarker response following multiple BPS804 administration in multiple dosing regimens.
- Trial name
- NCT01406548
- Testing
- BPS804 20mg/Kg
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Ultragenyx Pharmaceutical Inc
Osteoporosis, Fractures
Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study
The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.
- Conditions
- Osteoporosis, Fractures, HIV Infection
- Trial name
- Probono1 (NCT01669954)
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- King's College London
Shoulder Pain, Bone Mineral Density
BFR After Bicep Tenodesis
A randomized controlled pilot study evaluating the effect of occlusion training on bone density and function of the upper extremity following a biceps tenodesis.
- Conditions
- Shoulder Pain, Bone Mineral Density, Muscle Strength
- Trial name
- NCT03437239
- Testing
- Delfi PTS II Portable Tourniquet System
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Obesity, Osteoporosis
Milk Supplementation and Energy Balance.
The aim of the project is to determine if milk supplementation during a caloric restriction program facilitates the lost of weight, improves the appetite control and attenuates the decrease of bone mineral content in low-calcium…
- Trial name
- NCT00729170
- Testing
- Supplementation of milk (35% more calcium)
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Bone Loss, Age-Related,
Effect of the High Impact Exercise on Bone Density in Prepuberal Girls
Osteoporosis has become a worldwide concern an a matter of public health as osteoporosis is a major contributing factor associated with insufficiency fracture of the spine, wrist and proximal femur, and as a result, can diminish…
- Trial name
- NCT02488122
- Testing
- High Impact Exercise, Low Impact Exercise
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Autism Spectrum Disorder, Bone Diseases, Developmental
Bone Mass Accrual in Children With Autism Spectrum Disorder
This is a observational study to investigate the degree to which bone mineral density is impaired in boys with autism compared with typically developing controls.
- Trial name
- NCT03162445
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis
Roentgen Stereophotogrammetric Analysis (RSA) Trial Comparing Trabecular Metal Monoblock and Modular Tibial Components
Total knee replacement is an effective option for treating chronic knee conditions that cause pain and functional impairment. Significant improvements in quality of life, as measured by both disease specific and generic quality…
- Trial name
- NCT01180595
- Testing
- Trabecular Metal Modular Tibial Total Knee Component, Trabecular Metal Monoblock Tibial Total Knee Component
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Dalhousie University
Duchenne's Muscular Dystrophy, Scoliosis
Test-Retest Reliability of Pulmonary Function Tests in Patients With Duchenne's Muscular Dystrophy
Nearly all patients with Duchenne's Muscular Dystrophy (DMD) have scoliosis. Posterior instrumented spinal fusion, which is a surgery to correct scoliosis, has been shown to improve quality of life and satisfaction of both…
- Trial name
- NCT00207857
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta
Muscular Dystrophy, Duchenne Muscular Dystrophy,
Study Safety and Efficacy of Bone Marrow Derived Autologous Cells for the Treatment of Muscular Dystrophy.
This Study is single arm, single centre trial to check the safety and efficacy of Bone Marrow derived autologous cell(100 million per dose) for the patient with Duchenne Muscular Dystrophy.
- Trial name
- mdp (NCT01834066)
- Testing
- Stem Cell
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Women, Osteoporosis
Temporomandibular Disorders and Osteoporosis
Increased life expectancy has attracted research attention, interested in provide a quality and healthy aging. According to the latest census conducted in 2010 by IBGE, Brazilian population consists of 97,342,162 women, whom…
- Conditions
- Women, Osteoporosis, Osteopenia, Temporomandibular Disorder
- Trial name
- TMDOST (NCT01029210)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bone Injury
Salivary Bmp-2 Levels & Radiographic Measurement Of Bone Density at Extracted Tooth
Salivary Bmp-2 Levels \& Radiographic Measurement Of Bone Density were evaluated At Extracted Tooth Socket in patients With \& Without topical Application Of Simvastatin
- Trial name
- salivaryBMP2 (NCT05369091)
- Testing
- Simvastatin 10mg
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Postgraduate Medical Institute, Lahore
Rheumatoid Arthritis
Rheumatoid Arthritis Comorbidity: Bone Health in Men and African Americans
The objective of the proposed study is to assess bone health and determinants of bone health among select subpopulations of rheumatoid arthritis patients.
- Trial name
- NCT00595894
- Where
- United States
- Volunteers
- 1,745 people
- Sponsor
- University of Nebraska
Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity
Bioactive Glass as Bone Graft Substitute in Operative Treatment of Bone - a 10 Years Follow-up Study
The main aim is to evaluate the long-term safety and bone healing in the operated area and to compare bioactive glass granules with autogenous bone as a filler material.
- Conditions
- Depressed Lateral Condyle Fracture, Benign Bone Tumour Cavity, Spinal Fusion
- Trial name
- NCT00935870
- Testing
- Bioactive glass and/or autogenous bone
- Where
- Finland
- Volunteers
- 63 people
- Sponsor
- Vivoxid Ltd
Osteoporosis
Osteoporosis Prevention in Preadolescent Girls
This study will test an osteoporosis prevention program aimed at preadolescent girls between the ages of 10 and 12 who have not yet started their menstrual periods.
- Trial name
- NCT00000413
- Testing
- Psychoeducational program
- Where
- United States
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Low Bone Density, Osteopenia
Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults
No clinical trials have evaluated strontium L-lactate (SrLac), the strontium salt of the L-enantiomer of lactic acid. Therefore, this clinical study was conducted to obtain general safety and pharmacokinetic (PK) information…
- Conditions
- Low Bone Density, Osteopenia, Osteoporosis, Postmenopausal
- Trial name
- NCT03761979
- Testing
- Strontium L-lactate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BioLink Life Sciences, Inc.
Becker Muscular Dystrophy, Muscular Dystrophies
Defining Endpoints in Becker Muscular Dystrophy
This is a 24-month, observational study of 50 participants with Becker muscular dystrophy (BMD)
- Conditions
- Becker Muscular Dystrophy, Muscular Dystrophies, Muscular Dystrophy in Children, Muscular Dystrophy, Becker
- Trial name
- GRASP-01-002 (NCT05257473)
- Where
- 11 sites in United States, New Zealand and 1 more
- Volunteers
- 80 people
- Sponsor
- Virginia Commonwealth University
Osteoporosis
The Treatment of Osteoporosis Using a Combination of Teriparatide (Forteo) and Denosumab
This is a three-year study to evaluate the effect of sequential therapy of Forteo (teriparatide) and denosumab on bone density at the spine, hip, leg and forearm.
- Trial name
- NCT02130973
- Testing
- Standard Clinical Practice Regimen, Experimental Cyclic Regimen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Health Research, Inc.
Duchenne Muscular Dystrophy
An Extension Study to Evaluate Casimersen or Golodirsen in Patients With Duchenne Muscular Dystrophy
The main objective of this study is to evaluate the safety and tolerability of long-term treatment with casimersen or golodirsen in patients with Duchenne muscular dystrophy (DMD).
- Trial name
- NCT03532542
- Testing
- Casimersen, Golodirsen
- Where
- 50 sites in United States, Belgium and 11 more
- Volunteers
- 171 people
- Sponsor
- Sarepta Therapeutics, Inc.