Clinical trials: BMI>35
LMA Vs I Gel
Randomized Comparative Study Between Classic Laryngeal Mask Airway and I Gel Airway in Obese Patients Having BMI 35-40 During Elective Non Abdominal Surgery.
Invistigators study both supraglottic airway devices; the classic LMA and the I GEL mask are satisfactory devices providing high airway leaking pressures.
- Trial name
- NCT03843827
- Testing
- Laryngeal Mask Airway, I gel Airway
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Morbid Obesity
Oxygenation and Pulmonary Function in Morbidly Obese Patients Undergoing Bariatric Surgery
This is a randomized controlled study in which morbidly obese patients undergoing bariatric surgery will be recruited in the preoperative clinic.
- Trial name
- NCT01002599
- Testing
- Boussignac TM CPAP, Venturi Face Mask
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University Health Network, Toronto
Type 2 Diabetes
Diet and Medical Therapy Versus Bariatric Surgery in Type 2 Diabetes
It is generally held that ß-cell function is irreversibly lost already at the time the disease manifests itself and thereafter continues to decline linearly with time.
- Trial name
- DIBASY (NCT00888836)
- Testing
- Bariatric surgery: Gastric bypass, Bariatric surgery: Bilio-pancreatic diversion, anti-diabetic drugs and behavioral suggestions
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity, Morbid
Tracheal Intubation in Morbidly Obese (BMI>35) and in Lean (BMI<30) Patients Using McGrath MAC X-Blade
80 lean (BMI<35) and morbidly obese (BMI>35) patients undergoing elective surgery were enrolled in this prospective ransomİzed study were intubated using McGrath MAC X-Blade.
- Trial name
- NCT03759990
- Testing
- lean, obese
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kocaeli University
Obesity, Pregnancy
Sleep Apnea, Obesity and Pregnancy
Main objective: Determine the prevalence of obstructive sleep apnea syndrome (OSA) in late pregnancy in a population of obese patients .
- Trial name
- GOS (NCT02029859)
- Testing
- Polygraphic examination
- Where
- 4 sites in France
- Volunteers
- 205 people
- Sponsor
- University Hospital, Rouen
Obese
Mechanical Ventilation in Obese Surgical Patients
The purpose of this study is to evaluate whether an intraoperative positive end-expiratory pressures (PEEP) setting strategy aimed at minimizing the mechanical power delivered to the lungs via transpulmonary pressure improves…
- Trial name
- NCT07774065
- Testing
- Standard PEEP (8 cmH₂O)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Obesity, Obesity, Morbid
Comparing Anti-XA Levels in Post-Cesarean Patients Undergoing Enoxaparin Thromboprophylaxis
Pregnant and recently postpartum women are at significantly higher risk of developing a blood clot in their arms or legs known as a deep venous thrombosis (DVT) and/or a blood clot in their lungs known as a pulmonary embolism…
- Conditions
- Obesity, Obesity, Morbid, Pregnancy, Complications; Cesarean Section
- Trial name
- NCT02070237
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Obese
Addressing Place and People Micro Environments in Weight Loss Disparities
The purpose of this study is to A) capture obesogenic cues that occur in daily life, and B) to deliver cue alerts. Investigators hypothesized that A) black women experience more cues, B) racial disparities in obesity are reduced…
- Trial name
- APP-ME (NCT03083964)
- Testing
- Usual Care, Priming
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obesity With BMI >35
Omentopexy With Glubran®2 for Reducing Complications After Sleeve Gastrectomy
BACKGROUND. Gastric fistulas, bleeding, and strictures are commonly reported after laparoscopic sleeve gastrectomy (LSG), that increase morbidity and hospital stay and may put the patient's life at risk.
- Trial name
- NCT03833232
- Testing
- omentopexy with cyanoacrilate glue
- Volunteers
- 90 people
- Sponsor
- University of Salerno
Critical Illness, Acute Respiratory Failure
Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP)
The specific aim of the proposed study is to conduct a pilot study involving 160 critically-ill lean and obese patients enrolled at 11 sites in Canada, the United States of America, Belgium and France in order to: Specific Aims…
- Trial name
- TOP-UP (NCT01206166)
- Testing
- Olimel (5.7%E / N9E)
- Where
- 12 sites in United States, Belgium and 2 more
- Volunteers
- 125 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Eating Disorders, Severe Obesity
Severe Obesity and Eating Habits (OSCAR)
In anorexia nervosa,the eating disorder (ED) is the cause of thinness. In severe obesity, the overweight is a symptom. This symptom, however, is only the consequence of possibly deregulated eating behavior.
- Trial name
- OSCAR (NCT04588610)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Arras
Obesity, Liver Cirrhosis
Endoscopic Intragastric Balloon Placement for Weight Loss in Liver Transplant Waitlist Candidates
The purpose of this study is to determine whether the Orbera Intragastric Balloon is a safe and effective means for weight loss and improved metabolic disease in patients with cirrhosis requiring liver transplantation.
- Trial name
- NCT02556138
- Testing
- ORBERA Intragastric Balloon
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Overweight, Obesity
Dietary Supplements and Personal Energy Tracking Device to Promote and Maintain Healthy Weight
Excessive body weight is becoming a concern around the world, for example over half of the American adult population is overweight or obese.
- Trial name
- NCT00502658
- Testing
- Dietary supplement containing vitamins, minerals, and herbs, Shakes with nutrients and herbs, Control dietary supplement
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Osteoarthritis, Knee, Obesity
The POMELO (Prevention Of MusclE Loss in Osteoarthritis) Trial
Treatment options for individuals who have advanced knee osteoarthritis (OA) and a body mass index (BMI) ≥35 kg/m2 are limited, and this patient population may be neglected in current clinical care pathways for OA management.
- Trial name
- POMELO (NCT05026385)
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Diabetes
Comparative Effectiveness of Bariatric Surgery Versus Medical Management to Induce Diabetes Remission in Diabetic Patients With BMI 30-35
Specific Aims \& Hypothesis Primary Aim: To evaluate laparoscopic bariatric surgery versus intensive medical weight management on indices of insulin resistance and resolution of type 2 diabetes among patients with BMI 30-35.
- Trial name
- NCT01423877
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- NYU Langone Health
Glucose Metabolism, Lipid Metabolism
Effects of 10-gram Collagen Protein Hydrolysate on Cardiometabolic Health
The effects of a 10g/day collagen hydrolysate for a period of 4 weeks on glycemic control and cardiovascular health in a parallel design study using overweight/ obese men and women who are likely to have a disturbed lipid and…
- Trial name
- NCT05282641
- Testing
- 10 g of collagen hydrolysate
- Where
- Netherlands
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Normal Healthy Volunteer, Safety After Oral Intake
A Research Study to Evaluate BLX-7006 in Healthy Adults
This study will test an oral medicine called BLX-7006, which acts like the hormone Glucagon-like Peptide-1 (GLP-1) to help control blood sugar and body weight. Current GLP-1 medicines are given by injection.
- Trial name
- NCT07140055
- Testing
- BLX-7006
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Biolexis Therapeutics
Type 2 Diabetes Mellitus
A Surgical Approach to the Management of Type II Diabetes Mellitus in Patients With a BMI Between 25-35 kg/m2
The purpose of the study is to determine if by performing surgery we can cure Type II Diabetes. The surgical procedures: 1. a sleeve gastrectomy, cutting out a portion of the stomach, which provides restriction of caloric intake…
- Trial name
- NCT01197963
- Testing
- Sleeve Gastrectomy and Ileal transposition, dietary and medical management
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetes Mellitus
Multicentric Prospective Randomized Trial on Surgery Versus Standard Medical Care in Type 2 Diabetic Patients BMI 30-35
200 type 2 diabetic patients -BMI between 30-35- will be submitted to bariatric surgery (biliopancreatic diversion BPD or gastric bypass GBP ) and 100 will receive standard medical treatment.
- Trial name
- DIA-CHIR-MULT (NCT01041768)
- Testing
- Bariatric surgery
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Obesity, Obstructive Sleep Apnea
Evaluation of a Respiratory Monitor in Surgical Patients With a BMI>35
This study proposes to evaluate the clinical applicability of the ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA) in obese surgical patients undergoing general anesthesia.
- Trial name
- NCT01825278
- Testing
- ExSpiron Respiratory Volume Monitor (RVM, ExSpiron™, Respiratory Motion, Inc.; Waltham, MA
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Tufts Medical Center