Clinical trials: BMI
Alcohol Use Disorder (AUD), Obesity (BMI Equal to or >30)
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
This study will examine two doses of 1.0 mg and 2.0 mg of Semaglutide versus placebo in patients with Alcohol Use Disorder (AUD) and Obesity (Ob) to assess if these doses improve alcohol craving, stress and alcohol use outcomes.
- Trial name
- SEMA AUD (NCT07772960)
- Testing
- Semaglutide 1.0 mg, Semaglutide 2.0 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
Obesity (BMI>30), Obesity (BMI > 35)
FABP4 Response After Roux-en-Y Gastric Bypass
This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months.
- Conditions
- Obesity (BMI>30), Obesity (BMI > 35), Insulin Resistance, Bariatric Surgery
- Trial name
- FABP4-RYGB (NCT07774208)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
Overweight and Obese Adults, BMI >= 23
Dose Response of Leucine on Muscle Maintenance During Weight Loss
The objective of this research is to determine if there is dose response of leucine on muscle maintenance during 4-week of alternate-day fasting (ADF) on blood parameters, body composition, mood and parameters related to appetite…
- Trial name
- NCT07583875
- Testing
- leucine
- Where
- Singapore
- Volunteers
- 92 people
- Sponsor
- Nanyang Technological University
Infertility (IVF Patients), BMI
BMI Versus Body Fat Percentage - Which is the Better Predictor of Fertility Outcomes in IVF Cycles?
The goal of this prospective observational cohort study is to evaluate whether body composition measured using bioelectrical impedance analysis (BIA) (including measures of body fat% and visceral fat) serve as a better predictor…
- Conditions
- Infertility (IVF Patients), BMI, Bioelectrical Impedance Analysis, IVF Outcomes
- Trial name
- NCT07765368
- Testing
- Measurement of BIA (Body Fat and Visceral Fat Percentage)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation
This is a pilot research study to investigate the effects of a probiotic supplement (L. acidophilus, strain TW01) on substances found in the stool and bloodstream, gut bacteria composition, body composition, as well as any…
- Trial name
- NCT06912100
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Knee Arthritis Osteoarthritis, Knee Replacement Arthroplasty
Is BMI Outdated in TKA Patient Selection? Assessment of the Impact of Pre-tubercular Subcutaneous Tissue Thickness and the Risk of Postoperative Infection Following Total Knee Arthroplasty
While Body Mass Index (BMI) is currently used as a primary tool for risk stratification in patients undergoing Total Knee Athroplasty(TKA), its limitations raise concerns regarding its accuracy and fairness in guiding surgical…
- Conditions
- Knee Arthritis Osteoarthritis, Knee Replacement Arthroplasty, BMI, Regional Body Composition
- Trial name
- BEYOND-BMI (NCT07763535)
- Volunteers
- 400 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Healthy, Overweight (BMI > 25)
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or…
- Conditions
- Healthy, Overweight (BMI > 25), Overweight , Obesity, Male
- Trial name
- ProBiSat (NCT07715955)
- Testing
- Probiotic supplementation
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Adolescents (12 to 17 Years Old), Obese (BMI>90th Percentile)
Teenagers: Impact of Eccentric eXercise Training on Overweight and Obesity
Nowadays, eccentric exercise can be realized in a dynamic way with an ergocycle which permits eccentric (ECC) lower limbs contractions at a defined power output.
- Trial name
- TEXTOO (NCT02925572)
- Testing
- Cycling exercises
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
Obesity (BMI > 35), Morbid Obesity
Predictive Value of Nutritional and Inflammatory Indices for Postoperative Complications After Bariatric Surgery
Bariatric surgery is an effective treatment for severe obesity, but postoperative complications remain an important cause of morbidity.
- Trial name
- BARI-NUTRI (NCT07747168)
- Testing
- Bariatric Surgery
- Where
- Greece
- Volunteers
- 600 people
- Sponsor
- G.Gennimatas General Hospital
Severe Obesity, Obesity
GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial
The goal of this pilot clinical trial is to determine the effectiveness of Tirzepatide in patients with persistent obesity (BMI \> 30) 12 months after bariatric surgery (Roux-en-Y Gastric Bypass).
- Conditions
- Severe Obesity, Obesity, BMI Greater Than 30
- Trial name
- GRABS-0 (NCT06162715)
- Testing
- Tirzepatide, Standard of Care post-gastric bypass
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Obesity, Overweight (BMI > 25)
CHANGES IN SLEEP QUALITY AND BODY COMPOSITION FOLLOWING A MULTIMODAL LIFESTYLE INTERVENTION IN OLDER WOMEN
This single-arm pilot study evaluated changes in sleep quality, body composition, biochemical parameters, physical activity, and psychological well-being following a 12-week multimodal lifestyle intervention in overweight and…
- Conditions
- Obesity, Overweight (BMI > 25), Sleep Quality, Body Composition
- Trial name
- NCT07740902
- Testing
- Multimodal Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Obese Adults, BMI/Body Composition
Precision Lifestyle Medicine Program for IFHAS Participants
The goal of this clinical trial is to evaluate whether a precision lifestyle medicine intervention can improve cardiometabolic health in Emirati adults aged 25 to 50 years living in Abu Dhabi with obesity (BMI 30-35 kg/m²) who…
- Conditions
- Obese Adults, BMI/Body Composition, Cardiometabolic Risk, Cardiovascular Disease Risk
- Trial name
- NCT07742917
- Testing
- Precision Lifestyle Medicine Program, Standard IFHAS Care
- Where
- United Arab Emirates
- Volunteers
- 150 people
- Sponsor
- Institute for Healthier Living Abu Dhabi
Obesity (BMI > 35), Bariatric Surgery
Digital Follow-Up and Nursing Education in Bariatric Surgery Patients
This randomized controlled experimental study aims to evaluate the effect of a PHP-MySQL database-based digital follow-up system combined with structured nursing education on quality of life, body mass index (BMI), and exercise…
- Trial name
- DigiBarQoL (NCT07457034)
- Testing
- Structured Nursing Education and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Okan University
Obesity (BMI>30)
Exercise and Taurine Supplementation on Intramuscular Fat in Older Women With Obesity
This randomized clinical trial aims to investigate the effects of multicomponent concurrent exercise training associated or not with taurine supplementation on intramuscular fat infiltration, physical performance, transcriptomic…
- Trial name
- TAUMUSCLE (NCT07730255)
- Testing
- Concurrent Exercise Training, Taurine
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Lower Back Pain, Obesity (BMI>30)
Semaglutide for Low Back Pain
Low back pain is the leading cause of disability in the United States, and obesity is a major risk factor for its development. GLP-1 receptor agonists such as Semaglutide have emerged as effective weight loss agents that may also…
- Conditions
- Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 Agonist
- Trial name
- NCT07731256
- Testing
- Semaglutide (administered by PDS290 pen-injector)
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Washington University School of Medicine
Obesity (BMI>30), Metabolically Healthy Obesity
Plasma Taurine in Older Women With Obesity: Impact of Metabolic Phenotype and Combined Exercise
Population aging has been accompanied by a rise in obesity and other chronic diseases, increasing cardiovascular risk particularly among women, who exhibit a higher prevalence in older age groups compared to men.
- Conditions
- Obesity (BMI>30), Metabolically Healthy Obesity, Metabolically Unhealty Obese
- Trial name
- non applicable (NCT07711899)
- Testing
- Physical Training of 16 weeks
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity (BMI>30)
MRI Assessment of Body Composition in Bariatric Surgery
The goal of this observational study is to evaluate changes in adipose tissue and skeletal muscle distribution using magnetic resonance imaging (MRI) in adults with obesity undergoing bariatric surgery.
- Trial name
- COMPOSE (NCT07711925)
- Testing
- MRI
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity
Effect of Ketone Esters on Liver Fat Content and Metabolic Function
The goal of this clinical trial is to determine whether ingestion of a ketone ester drink helps improve liver health and blood glucose control.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight (BMI > 25)
- Trial name
- JV (NCT07097506)
- Testing
- bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Surgery Date, Age
Quality of Life of Patients Who Have Undergone Bilateral Mastectomy
The investigators therefore aim to determine whether the type of mastectomy (preventive in a high-risk patient or therapeutic in a patient with a history of cancer), as well as the timing (immediate or delayed) and type of breast…
- Conditions
- Surgery Date, Age, BMI, Height
- Trial name
- RM BREAST Q (NCT07699913)
- Volunteers
- 115 people
- Sponsor
- University Hospital, Grenoble
Fasting, Obesity (BMI>30)
The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix
The interventional study will recruit four groups (n=10 per group): Young men and women with normal weight (BMI 18-25), and young men and women with obesity (BMI >30).
- Conditions
- Fasting, Obesity (BMI>30), Sex Difference
- Trial name
- GlycoFast84 (NCT07692646)
- Testing
- Diet
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen