Clinical trials: BPD
Borderline Personality Disorder
Training of Neural Responding in BPD
Emotion-related brain activation is made visible for patients via neurofeedback with the aim to improve discriminability of emotional arousal and emotion regulation.
- Trial name
- IP5n (NCT02866110)
- Testing
- Neurofeedback, MRI
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Central Institute of Mental Health, Mannheim
BPD - Bronchopulmonary Dysplasia
Randomized Control Trial: Synchronized Non-invasive Positive Pressure Ventilation Versus Non Synchronized Non Invasive Positive Pressure Ventilation in Extremely Low Birth Weight Infants
Infants delivered weighing less than 1 kg at birth (ELBW) are at high risk for the development of bronchopulmonary dysplasia (BPD) and Ventilator-Induced Lung Injury (VILI), in part because of the need for mechanical ventilation…
- Trial name
- NCT03613987
- Testing
- NAVA technology to synchronize NIPPV
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York Medical College
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
BPD Saturation TARgeting
Bronchopulmonary dysplasia (BPD), or chronic lung disease of prematurity, affects nearly half of extremely preterm infants.This study evaluates the use of supplemental oxygen to manage infants with established BPD.
- Conditions
- Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Chronic Lung Disease
- Trial name
- BPD STAR (NCT03385330)
- Testing
- LOWER oxygen saturation target group, HIGHER oxygen saturation target group
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Philadelphia
Parent-child Problem, Borderline Personality Disorder
Supportive Program for Mother With BPD
Borderline Personality Disorder (BPD) is characterized by a pervasive pattern of instability of interpersonal relationships, self-image and emotions as well as marked impulsivity.
- Trial name
- PAM-B (NCT02203708)
- Testing
- Supportive Program for Mother with BPD (SuPMother-B).
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Bronchopulmonary Dysplasia
Analysis of BPD in Premature Infants With Typical Imaging Changes
Bronchopulmonary dysplasia (BPD) is a common chronic respiratory disease in preterm infants. The increase in the survival rate of premature babies following the improvement of perinatal treatment and care has caused an increase…
- Trial name
- NCT04163822
- Testing
- no intervention
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Wang Jianhui
BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity
Early Caffeine in Preterm Neonates
This is a clinical trial which will investigate whether administration of caffeine, a respiratory stimulant, to preterm babies soon after birth can prevent the need for a breathing tube, or intubation.
- Conditions
- BPD - Bronchopulmonary Dysplasia, Apnea of Prematurity, Hemodynamic Instability, Intubation
- Trial name
- NCT03086473
- Testing
- Caffeine Citrate
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Jennifer Shepherd
Borderline Personality Disorder (BPD), PTSD - Post Traumatic Stress Disorder
Pilot Study for the Evaluation of a New Psychotherapeutic Treatment for Borderline Personality Disorder Patients With Post-traumatic Stress Symptoms
Borderline Personality Disorder (BPD) is a serious mental health condition that often co-occurs with Complex PTSD (CPTSD), making treatment more challenging.
- Trial name
- MBT-TF (NCT07305155)
- Testing
- Standard Mentalization-Based Treatment, Trauma-Focused Mentalization-Based Treatment
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Eva Rüfenacht
Borderline Personality Disorder
Cognitive Control of Negative Stimuli in BPD
Borderline personality disorder (BPD) is characterized by impairments in the cognitive control of negative information. These impairments in cognitive control are presumably due to blunted activity of the dorsolateral prefrontal…
- Trial name
- NCT03636139
- Testing
- transcranial DC stimulation : anodal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Bronchopulmonary Dysplasia
Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants
The phase 1/2 trial aims to evaluate the safety and efficacy of EXOB-001 consisting of extracellular vesicles derived from umbilical cord mesenchymal stromal cells in the prevention of bronchopulmonary dysplasia (BPD) in…
- Trial name
- EVENEW (NCT06279741)
- Testing
- Endotracheopulmonary Instillation, Suspension
- Where
- 8 sites in Belgium, Italy
- Volunteers
- 265 people
- Sponsor
- EXO Biologics S.A.
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago
Bronchopulmonary Dysplasia
129Xe MRI in Pediatric Population With BPD
Hyperpolarized (HP) gas magnetic resonance imaging (MRI) of the lungs offers additional information that cannot be obtained with CT scan, the current gold standard for imaging this disorder.
- Trial name
- NCT04035629
- Testing
- MagniXene, hyperpolarized 129Xe MRI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Xemed LLC
The Relationship Between Oral Vitamin A Administration and the Incidence of BPD in Preterm Infants Born Before Week 29 of Pregnancy
Vitamin A for BPD Prevention
Chronic bronchopulmonary dysplasia (BPD) is a very common complication in preterm infants born at a young gestational age, and is a serious disease that impairs respiratory long-term outcome and is associated with…
- Trial name
- NCT04563429
- Testing
- Oral Vitamin A
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Bronchopulmonary Dysplasia
Intratracheal Umbilical Cord-derived Mesenchymal Stem Cell for the Treatment of Bronchopulmonary Dysplasia (BPD)
Umbilical Cord-derived Mesenchymal stem cell has been proven effective in the experimental bronchopulmonary dysplasia (BPD).A multi-center study was designed to evaluate the safety and efficacy of the cellular therapy in…
- Trial name
- IUMTB (NCT03645525)
- Testing
- Human Umbilical Cord-derived Mesenchymal stem cell
- Where
- 3 sites in China
- Sponsor
- Children's Hospital of Fudan University
Borderline Personality Disorder
Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument
Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and…
- Trial name
- NCT05831852
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD)
Implementing a Therapy for Complex Trauma in French-Speaking Settings
Many individuals living with borderline personality disorder (BPD) have experienced childhood trauma, such as abuse or neglect. A significant number of them also meet the criteria for post-traumatic stress disorder (PTSD).
- Conditions
- Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- TRAUL (NCT07123974)
- Testing
- Dialectical Behaviour Therapy for Post-Traumatic Stress Disorder (DBT-PTSD)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Borderline Personality Disorder
Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD)
The Primary objective of this study is to evaluate Seroquel XR in the treatment of borderline personality disorder (BPD). As in many initial randomized control trials, the study will be of relatively short duration - 8 weeks - to…
- Trial name
- NCT00880919
- Testing
- quetiapine extended-release
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Minnesota
Plasma Cell Myeloma
Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma
This phase II trial studies the effect of belantamab mafodotin, pomalidomide, and dexamethasone in treating patents with high-risk myeloma.
- Trial name
- NCT05208307
- Testing
- Belantamab Mafodotin, Dexamethasone, Pomalidomide
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Borderline Personality Disorder, Self-Injurious Behavior
N-Acetylcysteine in Adjunct to DBT for the Treatment of Self-Injurious Behavior in BPD
Self-Injurious Behavior (SIB) is a dangerous and common symptom in Borderline Personality Disorder (BPD) patients. Approximately 70% of patients with BPD engage in SIB at some point, compared to 17.5% of patients with other…
- Trial name
- NCT00539188
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Respiratory Distress Syndrome in Premature Infant
A Dose-Ranging Study to Determine the Efficacy, Safety and Tolerability of AeroFact
The purpose of this two-part Phase 2 study is to assess the safety, tolerability and efficacy of aerosolized SF-RI 1 (AeroFact) when delivered via nCPAP at two different doses.
- Trial name
- NCT03969992
- Testing
- AeroFact, nCPAP
- Where
- 41 sites in United States, Canada
- Volunteers
- 261 people
- Sponsor
- Aerogen Pharma Limited
Bipolar Disorder
Clinical Trial of Pramipexole in Bipolar Depression
The purpose of this study is to examine the safety and effectiveness of the drug pramipexole given in combination with lithium or divalproex for the short-term treatment of acute depression in patients with bipolar disorder.
- Trial name
- NCT00025792
- Testing
- Pramipexole
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)