Clinical trials: BPH (Benign Prostatic Hyperplasia)
BPH (Benign Prostatic Hyperplasia)
Predicting BPH Surgery Outcomes Using a Preoperative Scoring System
This study aims to develop and validate a preoperative predictive scoring system for surgical outcomes in patients with benign prostatic hyperplasia (BPH) undergoing prostate surgery (including but not limited to transurethral…
- Trial name
- NCT07623239
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Benign Prostatic Hyperplasia (BPH)
The Evaluation of Banana Flower Stamens Extract on Prevention of Benign Prostatic Hyperplasia in Adults
To assess the evaluation of banana flower stamens extract on prevention of benign prostatic hyperplasia in adults
- Trial name
- NCT04266418
- Testing
- Banana flower stamens extract
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms (LUTS)
Butterfly Pivotal Study
A prospective, multicenter, blind randomized (2:1) controlled study comparing the International Prostate Symptom Score (IPSS) of the Active arm to the IPSS of the control arm at the 3 months follow-up and active arm IPSS score…
- Trial name
- NCT05341661
- Testing
- Butterfly Prostatic Retraction Device
- Where
- 3 sites in United States
- Volunteers
- 245 people
- Sponsor
- Butterfly Medical Ltd.
BPH (Benign Prostatic Hyperplasia)
Convective Radio-frequency Water Vapor Energy Verses Trans-urethral Enucleation of Prostate for Management of Benign Prostatic Hyperplasia
Convective RF water vapor energy was introduced as a minimally invasive, radio-frequency thermal energy-based treatment, designed to convectively deliver sterile water vapor, or steam for targeted ablation limited to the…
- Trial name
- NCT07587333
- Testing
- Rezum, TUEP
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
BPH (Benign Prostatic Hyperplasia)
A Single-center, Single-arm Study to Evaluate the Safety and Efficacy of Ultra-minimally Invasive Prostate Dilation in Treating Patients With Significant Obstructive Symptoms Caused by Benign Prostatic Hyperplasia
This single-center, single-arm, prospective clinical study aims to preliminarily evaluate the safety and effectiveness of ultra-minimally invasive prostatic dilation using a prostate dilation catheter under real-time transrectal…
- Trial name
- UMPD-BPH (NCT07583706)
- Testing
- Prostate Dilation Catheter
- Where
- China
- Volunteers
- 5 people
- Sponsor
- Qing Yuan
Benign Prostate Hypertrophy(BPH)
Holmium Laser Enucleation Of the Prostate Versus Water Vapor Therapy Of The Prostate on Sexual Function and Ejaculation
This study aims to compare the effect of holmium laser enucleation of the prostate (HoLEP) versus water vapor therapy (Rezum) on sexual function and ejaculation in patients with benign prostatic hyperplasia (BPH).
- Trial name
- NCT07566689
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Water Vapor Thermal Therapy
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Benign Prostatic Hyperplasia (BPH)
A Trial to Investigate the Effectiveness and Safety of Org 3236 (Etonogestrel) Tablets in Men With Urinary Complaints Suggestive of a Benign Enlargement of the Prostate (304001)(P05806)
This trial is conducted to evaluate the effect of etonogestrel in comparison to placebo on: the prostate volume and the urinary complaints; the urinary flow and the urinary volume in the bladder after voiding; the progression of…
- Trial name
- NCT00651807
- Testing
- etonogestrel
- Where
- Argentina
- Volunteers
- 16 people
- Sponsor
- Organon and Co
Benign Prostatic Hyperplasia (BPH), Minimal Invasive Surgery
Minimally Invasive Prostate Interventions Registry (MIST Study)
This study is a multicenter prospective patient registry designed to evaluate clinical, functional, and safety outcomes after minimally invasive prostate interventions (MIST) performed for benign prostatic obstruction (BPO)…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Minimal Invasive Surgery, LUTS
- Trial name
- MIST (NCT07242807)
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Necmettin Erbakan University
BPH (Benign Prostatic Hyperplasia), Lower Urinary Track Symptoms
New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia
SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH).
- Trial name
- NCT06944145
- Testing
- raloxifene, Finasteride
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Beth Israel Deaconess Medical Center
BPH (Benign Prostatic Hyperplasia)
RT-310 Safety and Feasibility BPH Study
RT-310, is intended to deliver drug locally to the prostate gland for the management of prostate disease, while minimizing systemic exposure and its associated side-effects.
- Trial name
- NCT07264205
- Testing
- RT-310
- Where
- Dominican Republic
- Volunteers
- 20 people
- Sponsor
- Resurge Therapeutics Inc.
BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary
Evaluation of the Impact of Preoperative Pelvic Floor Exercise on Incontinence After Laser Enucleation of the Prostate: a Feasibility Study.
The purpose of this study is to assess the acceptability and feasibility of including a pelvic floor muscle exercise program into the care provided to patients undergoing prostate enucleation, studying both patients and…
- Conditions
- BPH (Benign Prostatic Hyperplasia), Incontinence, Urinary, HoLEP, Pelvic Floor Muscle Exercise
- Trial name
- PPP (NCT07456345)
- Testing
- Pelvic Floor Muscle Exercise before and after surgery
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
BPH (Benign Prostatic Hyperplasia)
Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the Prostate
The aim of this study is to evaluate the impact of daily tadalafil 5 mg on storage lower urinary tract symptoms (LUTS) during the early postoperative period following Anatomical endoscopic enucleation of prostate in a randomized…
- Trial name
- NCT07466030
- Testing
- Tadalafil 5mg (Male), Omiga 3
- Volunteers
- 40 people
- Sponsor
- Assiut University
BPH (Benign Prostatic Hyperplasia), BPH
INTUPRO in the Treatment of Benign Prostatic Hyperplasia-Related Symptoms
The goal of this clinical trial is to determine whether INTUPRO can improve the quality of life in patients with Benign Prostate Hyperplasia (BPH).
- Conditions
- BPH (Benign Prostatic Hyperplasia), BPH, BPH With Other Lower Urinary Tract Symptoms
- Trial name
- NCT07381127
- Testing
- INTUPRO ionic fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- inTumo Therapeutics, Inc.
Benign Prostatic Hypertrophy (BPH), Lower Urinary Track Symptoms
Intradetrusor Onabotulinumtoxin A (Botox) at the Time of Transurethral Resection of the Prostate or Transurethral Waterjet Ablation of the Prostate for Mixed Lower Urinary Tract Symptoms
Patients with longstanding obstructive lower urinary tract symptoms (LUTS) due to benign prostatic hypertrophy (BPH) can also develop symptoms of overactive bladder syndrome (OAB).
- Trial name
- NCT07377929
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Benaroya Research Institute
BPH (Benign Prostatic Hyperplasia)
Comparison of Holmium, Thulium:YAG, and Thulium Fiber Lasers in Prostate Enucleation
Benign prostatic hyperplasia (BPH) is a common condition in aging men and may require surgical treatment when medical therapy is ineffective.
- Trial name
- TRI-LASER (NCT07350005)
- Testing
- Holmium:YAG Laser Prostate Enucleation, Thulium:YAG Laser Prostate Enucleation, Thulium Fiber Laser Prostate Enucleation
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Ankara University
Benign Prostate Hypertrophy(BPH)
A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846
A Clinical trial to compare and evaluate evaluate the pharmacokinetics and safety of CKD-846
- Trial name
- NCT06110923
- Testing
- CKD-846, D091
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Acute Urinary Retention, Benign Prostate Obstruction
Early Versus Delayed Trial Without Catheter in Men With Acute Urinary Retention.
Acute urinary retention (AUR) is a sudden and painful condition. It occurs when a person is unable to urinate. In men, AUR is most often caused by an enlarged prostate, known as benign prostatic hyperplasia (BPH), which blocks…
- Conditions
- Acute Urinary Retention, Benign Prostate Obstruction, Benign Prostate Hyperplasia, Benign Prostate Hypertrophy(BPH)
- Trial name
- RELIEF (NCT07283484)
- Testing
- TWOC after 3 days, TWOC after 14 days
- Where
- 11 sites in Netherlands
- Volunteers
- 478 people
- Sponsor
- Liselot Ribbert
Benign Prostatic Hyperplasia (BPH)
TURP Outcome Prediction Calculator Study
The goal of this observational study is to identify which preoperative clinical, ultrasound, and uroflowmetry parameters can help predict the success of transurethral resection of the prostate (TURP) in adult male patients with…
- Trial name
- TURP-SCORE (NCT07277556)
- Volunteers
- 200 people
- Sponsor
- General Hospital Sveti Duh
Benign Prostate Hypertrophy(BPH)
Efficacy of Prostatic Arteries Embolization Using SQUIDPERI
Prostatic Artery Embolization (PAE) is a recognized mini-invasive treatment of bothersome Lower Urinary Tract Symptoms (LUTS) related to Benign Prostatic Hyperplasia (BPH).
- Trial name
- SQUID-PAE (NCT07255508)
- Testing
- Liquid embolic agent
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms
RT-310 Dose Escalation BPH Study
RT-310, a novel implant, is intended to minimally invasive treat locally the prostate gland for the management of prostate disease, while minimizing side-effects.
- Trial name
- NCT06136819
- Testing
- RT-310
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 20 people
- Sponsor
- Resurge Therapeutics Inc.