Clinical trials: BRONCHIAL ASTHMA
Asthma
SERETIDE Vs FLIXOTIDE In Mild Persistent Asthma (GINAII)
An 18 months randomised double-blind study with two parallel arms with start dose of inhaled SERETIDE 50/100mcg BD or FLIXOTIDE 100mcg BD, Phase I is 6 months where the patient will be up-titrated until well controlled is…
- Trial name
- NCT00455923
- Testing
- Seretide, Flixotide
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- GlaxoSmithKline
Asthma
Indirect Cost of Illness Study of Moderate and Severe Asthma in Quebec
Rationale Asthma is a chronic inflammatory disorder of the airways affecting persons of all ages and is recognized as one of the most common chronic diseases.
- Trial name
- NCT02153346
- Testing
- Valuation of lost productivity questionnaire, Work productivity and activity impairment questionnaire
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- GlaxoSmithKline
ASTHMA
Exhaled Air Temperature (TAE) As A Marker Of Airway Inflammation In Asthma
The goals : to develop and computerize equipment for measuring ITAE , compare the results with TAEP Itae study the possible relationship between different markers of inflammation: sputum eosinophils , FeNO , the ITAE and TAEP and…
- Trial name
- NCT02064686
- Testing
- Exhaled breath temperature
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Asthma
Using Computers to Assist in the Treatment of Asthma in a Pediatric Setting
This study seeks to improve physician adherence to four recommendations of the NHLBI asthma treatment guidelines: 1. Improve case detection of asthma among patients with pulmonary symptoms, 2.
- Trial name
- NCT01312805
- Testing
- CHICA Asthma Module, CHICA Control
- Where
- United States
- Volunteers
- 2,098 people, healthy volunteers welcome
- Sponsor
- Indiana University
Allergic Bronchopulmonary Aspergillosis
Trial on the Efficacy and Safety of Two Different Glucocorticoid Dose Regimens in Allergic Bronchopulmonary Aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder caused by a complex hypersensitivity response to antigens released by the fungus Aspergillus fumigatus.
- Trial name
- NCT00974766
- Testing
- Glucocorticoids
- Where
- India
- Volunteers
- 92 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Asthma
Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children
This study evaluates the effect of cumulative dose administration of albuterol sulfate inhalation aerosol delivered with valved holding chamber and facemask.
- Trial name
- NCT00144846
- Testing
- albuterol sulfate inhalation aerosol
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 80 people
- Sponsor
- GlaxoSmithKline
Atopy, Asthma
Vitamin A Supplementation at Birth and Atopy in Childhood
INTRODUCTION Eight trials studying the effect of providing neonatal vitamin A supplementation (NVAS) have been reported, and another four are underway to test whether NVAS should become WHO policy.
- Conditions
- Atopy, Asthma, Eczema, Food Allergy
- Trial name
- NCT01779180
- Where
- Guinea-Bissau
- Volunteers
- 2,000 people
- Sponsor
- Bandim Health Project
Asthma, COPD
Choice of Inhalation Device
In this study, asthma and COPD patients will be invited to participate after the consultation with their pulmonologist. The intervention consists of three steps. The first step is to perform a deep inspiration.
- Trial name
- Choice Device (NCT05264441)
- Testing
- In-Check DIAL G16
- Volunteers
- 140 people
- Sponsor
- Universitair Ziekenhuis Brussel
Asthma
Efficacy of FLUTIFORM ® vs Seretide® in Moderate to Severe Persistent Asthma in Subjects Aged ≥12 Years
A double blind, double dummy, randomised, multicentre, two arm parallel group study to assess the efficacy and safety of FLUTIFORM® pMDI (2 puffs bid) vs Seretide® pMDI (2 puffs bid) in subjects aged ≥12 years with moderate to…
- Trial name
- NCT03387241
- Testing
- Fluticasone/ Formoterol, fluticasone/ salmeterol
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Mundipharma (China) Pharmaceutical Co. Ltd
ASTHMA
Risk Factors Associated to Difficult-to-control Asthma
Several studies have demonstrated the efficacy of asthma treatment but despite being correctly diagnosed, conveniently prescribed and adherent to the therapeutics, 5% to 10% of asthmatics do not reach disease control.
- Trial name
- NCT01089322
- Testing
- inhaled corticosteroid plus LABA plus oral corticosteroid
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Rafael Stelmach
Atopic Dermatitis, Allergic Rhinitis
Prevention Allergic Disease of Infant With Probiotics During Pregnancy and Neonatal Period
The purpose of this study is to determine whether childhood atopic disease decrease or not after allowing allergic mothers intake of probiotic (Lactobacillus GG) in second trimester, followed by infant intake for 6 months after…
- Conditions
- Atopic Dermatitis, Allergic Rhinitis, Asthma
- Trial name
- NCT00325273
- Testing
- Lactobacillus rhamnosus GG
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Chang Gung Memorial Hospital
Asthma, Asthma in Children
ED-Initiated School-based Asthma Medication Supervision
Asthma is a common chronic condition that causes substantial morbidity among children and much of it is attributable to medication non-adherence.
- Trial name
- EDSAMS (NCT03952286)
- Testing
- ED-Dispensing home and school supervision
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Arizona
Allergic Conditions
Efficacy and Safety of LAIS® Mites Sublingual Tablets
Evaluation of the efficacy and safety of SLIT with LAIS® Mites Sublingual tablets compared to standard drug treatment in patients aged over 60 years suffering from house dust mite (HDM) induced allergic rhino-conjunctivitis…
- Trial name
- korLAIS (NCT02277483)
- Testing
- LAIS®
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Ajou University School of Medicine
Severe Asthma
Phase 3b Study in Patients With Severe Asthma Treated With Tezepelumab
This study aims to explore the potential for Tezepelumab-treated severe asthmatic patients to effectively and safely reduce their background maintenance medication while maintaining asthma symptom control.
- Trial name
- TAPER (NCT07363642)
- Testing
- Tezepelumab
- Where
- 75 sites in China
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Asthma in Children
A Comparative Study on the Efficacy of Different Stepping-down Therapy for Childhood Asthma
This study is a 24-week, randomized, parallel group comparative effectiveness study to evaluate the risk of stepping down therapy for patients with well-controlled asthma treated with combination Inhaled corticosteroids (ICS) and…
- Trial name
- NCT04953741
- Testing
- Fluticasone propionate inhaled aerosol
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xijing Hospital
Asthma
Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA)
The purpose of this study is to see whether a new investigational drug (Imatinib) may help improve asthma in people whose symptoms are not well controlled with high dose inhaled corticosteroid treatment.
- Trial name
- KIA (NCT01097694)
- Testing
- Imatinib mesylate
- Where
- 7 sites in United States
- Volunteers
- 176 people
- Sponsor
- Brigham and Women's Hospital
Asthma
Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma Participants
Primary Objective: To evaluate the effects of SAR440340 with or without dupilumab, compared to placebo, on reducing the incidence of "loss of asthma control" (LOAC) events.
- Trial name
- NCT03387852
- Testing
- SAR440340, Dupilumab, Fluticasone or Fluticasone/salmeterol combination
- Where
- 71 sites in United States, Argentina and 6 more
- Volunteers
- 296 people
- Sponsor
- Sanofi
Asthma, Care Management, Patient
Digital Prevention of Asthma
Asthma self-management is dependent on support and education. To facilitate self-management have we developed and CE-mark a novel digital self-management system called Asthmatuner (Medituner AB, Sweden).The primary aim of this…
- Trial name
- AsthmaTuner (NCT04132778)
- Testing
- AsthmaTuner
- Where
- 2 sites in Sweden
- Volunteers
- 331 people
- Sponsor
- Karolinska Institutet
Allergic Rhinitis, Asthma
Acupuncture for Rhinitis Complicated With Asthma
This randomized controlled study aimed to evaluate the efficacy and safety of acupuncture therapy on persistent allergic rhinitis patients complicated with asthma.
- Trial name
- NCT02033252
- Testing
- Acupuncture
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Jun-Yong Choi
Asthma
CARE - Quality Improvement in Asthma Secondary Prevention in Primary Care, Through Delegation of Consultations to the Nurse.
Quality Improvement in Primary Care: delegation of check-ups to nurses in general practice
- Trial name
- NCT00714038
- Where
- 93 sites in Denmark
- Volunteers
- 2,122 people
- Sponsor
- AstraZeneca
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