Clinical trials: BRONCHIAL ASTHMA
Asthma (Diagnosis), Persistent Asthma
Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA)
In this single center, interventional pilot study, 40 participants at high risk for future exacerbation will be randomized to anakinra (v.
- Conditions
- Asthma (Diagnosis), Persistent Asthma, Moderate Asthma Exacerbation
- Trial name
- ARTMA (NCT07600190)
- Testing
- Anakinra 100 Mg/0.67 Ml Inj Syringe
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma in Children, Exercise Induced Asthma
The Rainbow Study - the Effect of Feedback on Asthmatic Symptom Perception
Asthma is a common childhood disease that is characterized by chronic airway inflammation and episodic expiratory airflow obstruction.
- Trial name
- NCT06702735
- Testing
- Rainbow tool, Feedback
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Medisch Spectrum Twente
Asthma, Bronchoconstriction
Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol in Pediatric Subjects
The purpose of this study is to investigate, using an exercise challenge approach, the dose response of levalbuterol HFA MDI in pediatric subjects with asthma
- Trial name
- NCT00685347
- Testing
- Levalbuterol HFA MDI, Racemic Albuterol
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma, COPD
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
- Conditions
- Asthma, COPD, Interstitial Lung Disease, Cystic Fibrosis
- Trial name
- NCT04624490
- Testing
- Hyperpolarized Xe129
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Mario Castro, MD, MPH
Asthma, Lung Diseases
Risk Factors For Asthma in Laboratory Animal Allergy
To identify risk factors which predispose individuals to develop asthma and other manifestations of allergic disease on exposure to laboratory animals in the workplace.
- Trial name
- NCT00005283
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Covid-19 Infection, Hospitalization in Respiratory Disease Department
Protective Role of Inhaled Steroids for Covid-19 Infection
We hypothesize that inhaled steroid therapy and long acting beta 2 adrenergic agonist, widely prescribed in asthma patients, may also have a local protective effect against coronavirus infection, even in patients without asthma.
- Trial name
- INHASCO (NCT04331054)
- Testing
- 2: Usual practice + SYMBICORT RAPIHALER, 1: Usual practice
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 1, Epilepsy
Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context
Parents of children with long-term health conditions (LTCs) can experience shame related to parenting. Whilst self-compassion interventions (SCIs) can reduce parental shame, this has not been studied with parents of children with…
- Conditions
- Diabetes Mellitus, Type 1, Epilepsy, Asthma, Shame
- Trial name
- NCT03504605
- Testing
- Online self-compassion intervention
- Where
- United Kingdom
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Asthma Bronchial
Asthma and Primary Arterial Hypertension: an Inflammatory Link?
A low-intervention, prospective, experimental study will be conducted with the overall aim of assessing the inflammatory, functional and clinical differences between patients with asthma and those with asthma and hypertension, in…
- Trial name
- NCT07903805
- Testing
- measurement of inflammatory markers
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Asthma
Effect of Inhaled Ciclesonide in Adult Patients With Asthma (BY9010/M1-125)
Ciclesonide is a novel inhaled corticosteroid for the treatment of asthma. In this study the effect of ciclesonide on airway hyperresponsiveness (AHR), exhaled nitric oxide (NO), and induced sputum inflammatory biomarkers will be…
- Trial name
- NCT00546520
- Testing
- Ciclesonide
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- AstraZeneca
Steroids In Management Of Acute Asthma Exacerbations
Steroids In The Management Of Acute Asthma Exacerbations In Children, Which Form Is More Suitable?
The aim of this study is to compare the efficacy of a single dose of intramuscular dexamethasone versus 3 days of twice-daily oral prednisolone in the management of mild to moderate asthma exacerbations in children and test…
- Trial name
- NCT03204760
- Testing
- Dexamethasone 8Mg Solution for Injection, Prednisolone Oral, Per 5 Mg
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Asthma
Randomized, Placebo-controlled, Multi-dose, Study Comparing Budesonide/Formoterol to Symbicort® in Asthmatic Patients
A randomized multiple-dose, placebo-controlled, parallel group design consisting of a 2-week run-in period followed by a 6-week treatment period of the placebo, Test product (Budesonide 80 mcg / Formoterol fumarate dihydrate 4.5…
- Trial name
- NCT03015259
- Testing
- Budesonide/Formoterol fumarate dihydrate, Symbicort
- Where
- 95 sites in United States
- Volunteers
- 1,762 people
- Sponsor
- Kindeva Drug Delivery
Asthma, Respiratory Tract Disease
Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental Communities
The primary purpose of this pragmatic randomized clinical trial is to examine whether the addition of a phone-based multicomponent environmental intervention customized for Houston public housing residents with asthma will result…
- Conditions
- Asthma, Respiratory Tract Disease, Lung Diseases, Sinusitis, Chronic
- Trial name
- NCT05345080
- Testing
- Exposure-Reduction Intervention
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Baylor College of Medicine
Asthma
Effect of Inhaled Mometasone/Formoterol Versus Inhaled Fluticasone/Salmeterol in Asthma Patients
The purpose of this study is to investigate the effectiveness of inhaled mometasone/formoterol versus inhaled fluticasone/salmeterol on peripheral airway function in treatment of asthma.
- Trial name
- NCT02415179
- Testing
- Inhaled Mometasone/formoterol, Inhaled Fluticasone/Salmeterol
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Asthma
Bioequivalence Study of Montelukast 10 mg Tablets
The objective of this study was to confirm if two formulations of montelukast tablets are bioequivalent. Test product was Montelukast (10 mg tablets; GlaxoSmithKline) and reference product Singulair (10 mg tablets; Merck Sharp \&…
- Trial name
- NCT01943942
- Testing
- Montelukast 10 mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Rhinoconjunctivitis, Rhinitis
Efficacy and Safety of Grass Sublingual Tablet in Adults (P05238 AM3)(COMPLETED)
This purpose of this study is to determine the efficacy and safety of a grass sublingual (under-the-tongue) tablet.
- Conditions
- Rhinoconjunctivitis, Rhinitis, Conjunctivitis, Allergy
- Trial name
- NCT00562159
- Testing
- SCH 697243, Loratadine 10 mg Rescue Treatment, Olopatadine 0.1% Rescue Treatment
- Volunteers
- 439 people
- Sponsor
- ALK-Abelló A/S
Asthma
Potential Benefits of Black Seed Oil Supplementation on Asthma Inflammation and Outcomes
Traditionally, Black Seed (Nigella sativa) is a well-known food supplement and herbal product that has a wide range of medical claims (including asthma) that originate from different historical backgrounds.
- Trial name
- NCT02407262
- Testing
- Black seed oil
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- University College, London
Asthma, Status Asthmaticus
Bilevel Positive Airway Pressure (BiPAP) for the Treatment of Moderate to Severe Acute Asthma Exacerbations
Bilevel Positive Airway Pressure (BiPAP) is increasingly being reported as an effective and safe method of respiratory support for children with severe asthma exacerbations unresponsive to standard therapies and with impending…
- Trial name
- NCT02347462
- Testing
- Bilevel Positive Airway Pressure (BiPAP) (Trilogy BiPAP, Philips Respironics), Standard care
- Where
- Canada
- Sponsor
- University of British Columbia
Atopic Dermatitis (AD), Asthma
Post-authorization Safety Study in North America to Monitor Pregnancy and Infant Outcomes Following Administration of Dupilumab During Planned or Unexpected Pregnancy
The objective is to evaluate the potential effect of exposure to dupilumab in pregnancy compared to the primary comparison group of disease-matched pregnant women who are not exposed to dupilumab, and the secondary comparison…
- Trial name
- NCT04173442
- Testing
- dupilumab
- Where
- United States
- Volunteers
- 581 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
Allergic Asthma
Tiotropium Efficacy Against Allergen Induced Early Asthmatic Responses
The study will compare the effect of inhaled tiotropium versus placebo on allergen induced early asthmatic responses in individuals with atopic asthma.
- Trial name
- NCT04648813
- Testing
- tiotropium bromide monohydrate (Spiriva Respimat)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Saskatchewan
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