Clinical trials: BRONCHIAL ASTHMA
Asthma, Asthma; Eosinophilic
Mepolizumab and Physical Activity in Severe Asthma
Severe asthma is a debilitating condition associated with frequent symptoms, life-threatening exacerbations and corticosteroid side-effects.
- Trial name
- TEXAS (NCT05404763)
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Lille
Asthma
Induced Sputum Study (0000-065)
The primary goals of this study will be to implement innovative processing and detection assays to qualify induced sputum measurements of markers of allergen-induced airway inflammation.
- Trial name
- NCT00623714
- Testing
- Comparator: fluticasone
- Volunteers
- 13 people
- Sponsor
- Merck Sharp & Dohme LLC
Status Asthmaticus
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room
Asthma is the most common chronic illness of childhood. About 10% of children are affected. Not surprisingly, acute asthma exacerbations are one of the common reasons to visit pediatric emergency rooms (ER).
- Trial name
- NCT01524198
- Testing
- Budesonide, Normal saline
- Where
- Saudi Arabia
- Volunteers
- 945 people
- Sponsor
- King Saud University
Asthma
A Study to Compare the Effects of Two Propellants in Adults With Mild Asthma
This is a Phase IIa, multicentre, single dose, randomised, double blind, controlled, 2 way cross-over study to evaluate the potential for bronchoconstriction of the new HFA-152a propellant (single dose) versus the marketed…
- Trial name
- NCT05472662
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
Early Antiviral Responses to Rhinovirus Infection in Asthma
The bulk of the morbidity and mortality related to asthma is during periods of acutely increased symptomatology called 'exacerbations'. Roughly half of asthma sufferers experience such an exacerbation each year.
- Trial name
- NCT05050903
- Testing
- Rhinovirus infection
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma
A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype
This study will assess the efficacy and safety of GSK3511294 (Depemokimab) as an adjunctive therapy in participants with severe uncontrolled asthma with an eosinophilic phenotype.
- Trial name
- SWIFT-2 (NCT04718103)
- Testing
- GSK3511294
- Where
- 129 sites in United States, Australia and 9 more
- Volunteers
- 397 people
- Sponsor
- GlaxoSmithKline
Asthma
EmPhAsIS: Empowering Pharmacists in Asthma Management Through Interactive SMS
Between 8% and 12% of Canadians suffer from asthma. Although there are effective and inexpensive treatments, adherence to asthma treatment is amongst the lowest for all chronic diseases.The purpose of this study is to determine…
- Trial name
- NCT02170883
- Testing
- Interactive SMS, Usual care
- Where
- Canada
- Volunteers
- 271 people
- Sponsor
- University of British Columbia
Childhood Asthma
Using Buteyko Breathing Technique to Control Asthma in School-Age Children
Asthma is a complex condition that can impair not only the child's physical growth but also his optimal functional capacity and performance.
- Trial name
- NCT05390554
- Testing
- Buteyko Breathing Technique
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Mansoura University
Infection, Heart Failure
Remote Physician Care for Home Hospital Patients
This study examines the implications of providing remote physician care to home hospitalized patients compared to usual home hospital care with in-person/in-home physician visits.
- Conditions
- Infection, Heart Failure, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT04080570
- Testing
- Remote Visit
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Brigham and Women's Hospital
Asthma
Primary Care Pathway for Childhood Asthma
At least half of children with asthma have poor disease control, which can result in complications requiring emergency treatment and hospitalization.
- Trial name
- NCT02481037
- Testing
- Primary care clinical pathway, Asthma education, EMR embedded dashboard
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Alberta
Asthma
Development of a Breath Analyzer for Asthma Screening
Annually, asthma is responsible for 1 million emergency room visits, 400,000 hospitalizations, and 5000 deaths according to the NHLBI.
- Trial name
- NCT00386737
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ekips Technologies
Dermatitis, Allergies
Salmon in Pregnancy Study
The number of infants and children with allergic disease (dermatitis, allergies, asthma) has increased over the last several decades. This may be related to changes in diet.
- Conditions
- Dermatitis, Allergies, Asthma
- Trial name
- SiPS (NCT00801502)
- Testing
- Oily fish consumption, Control
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Effect of Sitaxsentan on Airway Remodeling in Severe Asthma
Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma
Introduction. Despite adequate steroid therapy, a subpopulation of approximately 10% of asthmatics develops severe persistent airflow obstruction.
- Trial name
- Sitax (NCT01050491)
- Testing
- sitaxentan
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Asthma
Study Evaluating Etanercept in Moderate to Severe Asthma
The primary objective of the study is to assess the efficacy and safety of etanercept 25 mg given twice weekly in subjects with moderate to severe persistent asthma.
- Trial name
- NCT00141791
- Testing
- Etanercept
- Where
- 13 sites in United States
- Volunteers
- 120 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Asthma
The Use of Rosiglitazone to Treat Asthma
Asthma is a common chronic disease characterized by airway inflammation and bronchoconstriction. This study utilizes the drug rosiglitazone (Avandia)to treat the effects of airway inflammation in patients with asthma.
- Trial name
- NCT00614874
- Testing
- rosiglitazone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Creighton University
Moderate Asthma
Study of Formoterol 6 mcg/Fluticasone 125 mcg by Eurofarma Laboratórios S.A. Versus Alenia® 6 mcg/200 mcg in Patients With Asthma (FORASMA)
This is a Phase 3, multicenter, randomized, parallel-group, open-label, non-inferiority clinical trial designed to evaluate the efficacy and safety of N0783 compared to Alenia® (Formoterol 6 mcg / Budesonide 200 mcg) in the…
- Trial name
- FORASMA (NCT07318350)
- Testing
- N0783, Alenia® (Formoterol 6 mcg / Budesonide 200 mcg)
- Sponsor
- Eurofarma Laboratorios S.A.
Asthma
Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)
We are doing this study to learn how genes affect the way that people, specifically Black people, respond to treatment for asthma.
- Trial name
- BELT (NCT01290874)
- Testing
- Tiotropium, Salmeterol, Formoterol
- Where
- 13 sites in United States
- Volunteers
- 1,070 people
- Sponsor
- Brigham and Women's Hospital
Asthma
ICATA Asthma Mechanistic Study
The purposes of this study are to determine the effects of omalizumab on cells involved in the allergic response, to evaluate predictors of response to omalizumab, and to determine whether response to omalizumab therapy is…
- Trial name
- NCT00377390
- Testing
- Omalizumab
- Where
- 4 sites in United States
- Volunteers
- 224 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Atopic Disease
Microbiome and Atopy in Mali
This study is about allergic diseases in people living in Mali. Allergic diseases can cause health problems like asthma or skin rashes.
- Trial name
- NCT07051902
- Where
- 2 sites in Mali
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma
Effect of Inhaled TD-8236 on Allergen-induced Asthmatic Response
This will be a randomized, double-blind, placebo-controlled study. The study will use a three-period, six-sequence, complete-block, cross-over study design to characterize two doses of inhaled TD-8236 compared to placebo in…
- Trial name
- NCT04150341
- Testing
- TD-8236
- Where
- 2 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- Theravance Biopharma
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