Clinical trials: BRONCHIAL ASTHMA
Food Allergy, Atopic Dermatitis
Primary Prevention of Atopic Disease by Perinatal Administration of Probiotics
Administration of probiotics to pregnant women from an atopic family and subsequently to their high-risk newborns results in prevention of the incidence or in a decrease of the severity of atopic disease during infancy.
- Conditions
- Food Allergy, Atopic Dermatitis, Asthma, Rhinitis
- Trial name
- NCT00200954
- Testing
- Probiotic bacteria
- Where
- Netherlands
- Volunteers
- 157 people
- Sponsor
- The Netherlands Asthma Foundation
Asthmatic
Laura Mitchell's Relaxation Versus Papworth Exercise in Ashmatic Patient
Asthma is a lung disease that is characterized by airway obstruction that is reversible either spontaneously or with treatment, airway inflammation, and increase airway responsiveness to a variety of stimuli.
- Trial name
- NCT05915845
- Testing
- Laura Mitchell's Relaxation technique, Papworth exercise
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Asthma
Efficacy and Safety of Roflumilast in Patients With Asthma (BY217/M2-012)
The aim of the study is to compare the effects of oral roflumilast with placebo on lung function in patients with asthma.
- Trial name
- NCT00073177
- Testing
- Roflumilast
- Where
- 41 sites in United States, Argentina and 3 more
- Volunteers
- 819 people
- Sponsor
- AstraZeneca
Acute Asthma
Optimal Albuterol Regimens for Acute Asthma Exacerbations: DBRCT Pilot Study
Our overall objective is to model a pediatric Acute Asthma Clinical Decision Rule (ADR) for personalized medicine by identification of treatment-response phenotypes that are important determinants of outcome.
- Trial name
- OARS (NCT01196377)
- Testing
- Albuterol
- Volunteers
- 16 people
- Sponsor
- Vanderbilt University Medical Center
Asthma
A Clinical Study to Evaluate Symbicort Turbuhaler Used 'as Needed' in Adults and Adolescents With Asthma
The purpose of this study is to test if Symbicort (budesonide/formoterol) Turbuhaler is effective in treating asthma when used 'as needed' in patients with milder asthma.
- Trial name
- SYGMA2 (NCT02224157)
- Testing
- budesonode bid + terbutaline 'as needed'
- Where
- 340 sites in Australia, Brazil and 23 more
- Volunteers
- 4,215 people
- Sponsor
- AstraZeneca
Asthma in Children
Telehealth Education for Asthma Connecting Hospital and Home
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a technology-enhanced educational intervention for caregivers and children who are hospitalized due to asthma.
- Trial name
- TEACHH (NCT04995692)
- Testing
- Telehealth Education for Asthma Connecting Hospital and Home, Standard Care (SC) Comparison Group
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Rochester
Larynx, Obstruction
CLE During Exercise Testing in Asthma
The purpose is to assess visualize the level of laryngeal obstruction and vocal cord dysfunction and to obtain more information on causes for dyspnea in asthma and severe asthma and to assess safety of CLE in patients with asthma…
- Conditions
- Larynx, Obstruction, Vocal Cord Dysfunction
- Trial name
- CLEtesting (NCT04168671)
- Testing
- Continuous laryngoscopy during exercise test
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Asthma
Efficacy and Safety Comparison of Albuterol Spiromax® and ProAir® Hydrofluoroalkane (HFA) in Pediatric Patients
This is a multicenter, randomized, double-blind, double-dummy, placebo-controlled, single-dose, 5-treatment, 5-period, 5-way crossover study in pediatric patients with persistent asthma.
- Trial name
- NCT01899144
- Testing
- Albuterol Spiromax, ProAir HFA
- Where
- 22 sites in United States
- Volunteers
- 61 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis)
Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease
Breathlessness is a common symptom in people with chronic lung and heart diseases. It can affect daily activities, quality of life, and overall health.
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis), Interstitial Lung Disease (ILD)
- Trial name
- V1BE (NCT07836764)
- Testing
- 1MSTS
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Jacob Sandberg
Asthma
Research in Severe Asthma (RISA) Trial
The purpose of this study is to evaluate the safety and efficacy of the Alair System for the treatment of severe refractory asthma.
- Trial name
- NCT00214539
- Testing
- Bronchial Thermoplasty with the Alair System, Control
- Volunteers
- 34 people
- Sponsor
- Boston Scientific Corporation
Subject Presenting Wheeze, COPD
Wheeze Detection Using Aevice Medical Device
The primary objective of this study is to determine if Aevice Medical Device can detect wheeze as accurately as a physician through auscultation.
- Conditions
- Subject Presenting Wheeze, COPD, Asthma
- Trial name
- NCT05194436
- Testing
- AeviceMD
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Aevice Health Pte. Ltd.
Asthma
Implementation of Evidence-based Breathing Retraining for Patients With Asthma in Region Zealand
This study aims to implement the evidence-based intervention breathing retraining into clinical care of patients with symptomatic asthma irrespective of asthma severity or comorbidities, and in a diverse multicentre setting to…
- Trial name
- EmBRAiZ (NCT05531370)
- Testing
- Breathing Retraining
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Naestved Hospital
Asthma
VENTURI (VENTilation Using Respiratory Imaging)
The purpose of the study is to enroll participants with uncontrolled asthma to evaluate the large and small airways and drug delivery utilizing two study drugs: Beclometasone dipropionate/Formoterol fumarate…
- Trial name
- VENTURI (NCT07282886)
- Testing
- Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrrolate pMDI, Fluticasone Furoate/Umeclidinium/Vilanterol 100 MCG/1 ACTUATION-62.5 MCG/1 ACTUATION-25 MCG/1 ACTUATION Inhalation Powder
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Asthma
A Follow-up Survey to Compare Stable Dosing (SERETIDE) With SYMBICORT, SMART, Maintenance and Reliever Therapy in One Inhaler in Moderate and Severe Asthmatics.
The purpose with this study is to describe in detail the control or lack of control of asthma, based on two different dosing strategies, regular treatment with SERETIDE in a stable dosing with short acting beta-2 agonists as…
- Trial name
- NCT00858286
- Testing
- Spirometry, PEF measurements and diary cards to evaluate control of Asthma
- Where
- Sweden
- Volunteers
- 56 people
- Sponsor
- GlaxoSmithKline
Severe Asthma
Phenotyping Asthma for Bronchial Thermoplasty
This study will evaluate a new imaging technology, called optical coherence tomography (OCT) to examine the asthmatic airways before and after bronchial thermoplasty, which is a new treatment option for severe asthmatic patients.
- Trial name
- NCT03435237
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Asthma, Occupational, Hypersensitivity
Measures for Bioaerosol Reduction in the Salmon Industry
Workers in the salmon industry are at risk of developing allergies and respiratory diseases, including asthma, due to occupational exposure to bioaerosols, i.e.
- Trial name
- SHInE (NCT05039229)
- Testing
- Nozzles (NZ), Cleaning of surfaces (CS)
- Where
- Norway
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Asthma
Outcomes From an Asthma Disease Management Program
Disease management is used to manage patients who have asthma and who are enrolled in a managed care health plan. To understand the effect of disease management on asthma severity and utilization, the investigators at Children's…
- Trial name
- NCT00137722
- Testing
- Education of providers and their staff, Case management, Payment for desired behaviors
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Bronchial Asthma, Eosinophilic Asthma
XC8 in the Treatment of Patients With the Eosinophilic Phenotype of Bronchial Asthma
A multicenter, double-blind, randomized, pilot study in parallel groups to assess the efficacy and safety of XC8 at a dose of 100 mg versus placebo over a 12-week treatment period in non-smoking patients with a confirmed…
- Trial name
- NCT04674137
- Testing
- XC8 100 mg
- Where
- 18 sites in Russia
- Volunteers
- 70 people
- Sponsor
- Chemlmmune Therapeutics LLC
Asthma
The Use of Exhaled Nitric Oxide in Conjunction With the Asthma Control Test to Determine Asthma Control in Pediatric Patients
The purpose of this study is to determine if exhaled nitric oxide (eNO) levels will be increased in pediatric patients with uncontrolled asthma as determined by the Asthma Control Test (ACT).
- Trial name
- NCT00575445
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Akron Children's Hospital
COPD, Asthma
AirSonea Wheeze Detection Study
The purpose of this study is to determine if the AirSonea device provides an objective assessment of breath sounds for the presence of wheeze in both medical and home environments.
- Trial name
- NCT01927172
- Testing
- AirSonea
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- iSonea
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