Clinical trials: BRONCHIAL ASTHMA
Moderate to Severe Asthma
A Study of CM310 in Subjects With Moderate to Severe Asthma
This study is a multi-center, randomized, double-blind, placebo-controlled Phase Ⅱ/Ⅲ clinical study to evaluate the efficacy, safety, PK characteristics, PD effects and immunogenicity of CM310 in subjects with moderate to severe…
- Trial name
- NCT05761028
- Testing
- CM310
- Where
- China
- Volunteers
- 600 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Eczema, Asthma
Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-up to 5 Years
The investigators had conducted a double-blind, randomized placebo-controlled clinical trial studying the effects of 6 months probiotics supplementation from birth on allergic disease and sensitization up to 2 years of age.
- Conditions
- Eczema, Asthma, Allergic Rhinitis
- Trial name
- NCT00365469
- Testing
- Probiotic
- Where
- Singapore
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Asthma
Pulmicort Respules(Budesonide Inhalation Suspension) vs Singulair, Children
A one year study comparing the safety and effectiveness of Pulmicort (0.5mg strength given once a day in the evening) with either 4 or 5mg strength SINGULAR (given once a day in the evening) in children with asthma aged 2 to 8.
- Trial name
- NCT00641472
- Testing
- Budesonide inhalation suspension, Montelukast Sodium
- Volunteers
- 380 people
- Sponsor
- AstraZeneca
Asthma
Exploring the Efficacy of myAsthma in Secondary Care
Asthma is a common lung condition that causes long-term breathing problems. There is no cure and if uncontrolled can be life threatening.
- Trial name
- STEERING (NCT04744272)
- Testing
- myAsthma
- Where
- United Kingdom
- Sponsor
- my mhealth Ltd
Asthma
A Trial of SHR-1703 in Asthma
SHR-1703 is a monoclonal antibody under development for severe asthma. This study is the first study in patients with asthma. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics ，pharmacodynamics…
- Trial name
- NCT05042401
- Testing
- SHR-1703
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Asthma
The Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol Trial
This research study will compare the treatment effects of three different asthma medications in asthma subjects whose asthma is well controlled when they take fluticasone, an inhaled corticosteroid.
- Trial name
- NCT00156819
- Testing
- fluticasone, montelukast, Fluticasone plus salmeterol
- Where
- 19 sites in United States
- Volunteers
- 500 people
- Sponsor
- JHSPH Center for Clinical Trials
Asthma
Efficacy and Safety Study to Compare Formoterol Fumerate in the Pressair DPI to the Foradil Aerolizer in Patient With Mild to Moderate Asthma
The purpose of this Phase II study is to evaluate efficacy and safety of inhaled formoterol fumarate in the Pressair DPI compared to the Foradil Aerolizer in patients with mild to moderate asthma.
- Trial name
- NCT01641081
- Testing
- Formoterol Fumarate in the Pressair DPI, Low Dose, Formoterol Fumarate in the Pressair DPI, High Dose, Foradil Aerolizer, Low Dose
- Where
- 29 sites in United States
- Volunteers
- 174 people
- Sponsor
- AstraZeneca
Asthma
Real-world Effectiveness of Combination Therapy in Asthma
This study will evaluate and compare the effectiveness of asthma management in patients with evidence of persistent asthma following a switch in asthma therapy to combination inhaled glucocorticosteroid (ICS) / long-acting…
- Trial name
- NCT01141465
- Testing
- Fluticasone / formoterol metered dose inhaler, Fluticasone / salmeterol dry powder inhaler, Budesonide / formoterol dry powder inhaler
- Where
- United Kingdom
- Volunteers
- 815,377 people
- Sponsor
- Research in Real-Life Ltd
Influenza Like Illness, Asthma
How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment.
- Conditions
- Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
- Trial name
- WGA (NCT01979588)
- Testing
- What's Going Around tool, Control
- Where
- United States
- Volunteers
- 206,703 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Asthma
Efficacy and Safety Study of Fluticasone Proponate Inhalation Solution in Adult and Adolescent Asthma
This is a multicentre, randomized, single-blind, active-controlled, parallel-group phase III local registration study for a treatment period of 12 weeks.
- Trial name
- NCT01687283
- Testing
- fluticasone propionate inhalation solution, budesonide suspension
- Where
- 25 sites in China
- Volunteers
- 316 people
- Sponsor
- GlaxoSmithKline
Exercise-Induced Asthma
Study of Oglemilast for the Prevention of Asthma.
The purpose of this study is to determine whether it is effective in the treatment of exercise-induced asthma and investigate the safety of oglemilast.
- Trial name
- NCT00322283
- Testing
- Oglemilast
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Forest Laboratories
Asthma
Mobile Phone Based Structured Intervention
Although asthma outcomes can be improved with structured care, less than half of people with asthma achieve good control. Part of the problem is poor adherence with self-monitoring and preventive drug regimes.
- Trial name
- NCT00512837
- Testing
- Mobile phone technology
- Where
- United Kingdom
- Volunteers
- 312 people
- Sponsor
- University of Aberdeen
Asthma
Inflammatory Mediators and microRNA Analysis in Premenstrual Asthma
A small number of women with asthma have an increase in asthma symptoms during the premenstrual or menstrual period. This study is being done to investigate the possible causes of this premenstrual increase in asthma symptoms and…
- Trial name
- NCT00837395
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ohio State University
Patient Satisfaction
Study to Evaluate Satisfaction and Usability of DuoResp® SPIROMAX® in Asthma and COPD Treatment
The main aim of the study is to investigate patient satisfaction in the treatment of asthma and COPD with the new device of DuoResp® Spiromax® and patient preference.
- Trial name
- NCT02384577
- Testing
- Budesonide, Formoterol Fumarate Dihydrate
- Where
- Germany
- Volunteers
- 4,034 people
- Sponsor
- Teva Pharma GmbH
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Allergic Asthma
Extracorporeal SPecific IgE Removal From the Plasma of Allergic Asthma Patients (ESPIRA-study)
In this study patients suffering from Immunoglobulin E (IgE) mediated asthma are treated with a method, called immune apheresis, that removes IgE from blood.
- Trial name
- ESPIRA (NCT02096237)
- Testing
- IgE adsorber
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Asthma
A Study of MEMP1972A in the Prevention of Allergen-Induced Airway Obstruction in Patients With Mild Asthma (SOLARIO)
This Phase II, double-blind, placebo-controlled, randomized, parallel-group study is designed to evaluate the efficacy, safety and tolerability of MEMP1972A when administered to patients by intravenous (IV) infusion for the…
- Trial name
- NCT01196039
- Testing
- MEMP1972A
- Where
- 7 sites in Canada, Sweden
- Volunteers
- 29 people
- Sponsor
- Genentech, Inc.
Asthma
Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma
The purpose of this study is to determine the efficacy of indacaterol 55µg once daily (and 27.5 µg twice) in QVA149 compared to 75 µg indacaterol monotherapy.
- Trial name
- QAB149 (NCT01959412)
- Testing
- Indacaterol 27.5 mcg, Indacaterol 37.5, Indacaterol 55 mcg
- Where
- 12 sites in United States
- Volunteers
- 91 people
- Sponsor
- Novartis Pharmaceuticals
Asthma
Comparison of Microglial Activation in Severe Asthma and Healthy Controls
The goal of this clinical trial is to learn about how asthma influences brain function. The main questions it aims to answer are: How airway inflammation in asthma affects the brain; and, Whether airway inflammation in asthma is…
- Trial name
- MAIA-SC (NCT06299592)
- Testing
- PET/MRI using [18F]FEPPA tracer
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Chronic Obstructive Pulmonary Disease, Asthma
Hyperoxia During Pulmonary Rehabilitation in Chronic Lung Disease - Does it Matter?
Chronic respiratory diseases are a global burden. Treatment options have improved in recent years, pulmonary rehabilitation plays a key role.
- Conditions
- Chronic Obstructive Pulmonary Disease, Asthma, Pulmonary Hypertension, Interstitial Lung Disease
- Trial name
- NCT06174207
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Eastern Switzerland University of Applied Sciences
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