Clinical trials: BRONCHIAL ASTHMA
Asthma
Assessment of PFT, Safety, and PK of Zileuton Injection in Asthma Patients
A single intravenous injection of zileuton (150 or 300 mg) will be administered to patients with stable asthma. The goals will be to determine if zileuton i.v.
- Trial name
- NCT00534625
- Testing
- zileuton
- Volunteers
- 36 people
- Sponsor
- Critical Therapeutics
Asthma
Study of Inhaled Glucocorticosteroid Administration in Asthma Patients
Once-daily inhaled glucocorticosteroids treatment can sufficiently control airway inflammation in asthma patients.
- Trial name
- NCT00559689
- Testing
- Budesonide,hydrofluoroalkane-beclomethasone dipropionate, Budesonide,hydrofluoroalkane-beclomethasone
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Hamamatsu University
Asthma
A Practical Model to Transform Childhood Asthma Care - Spirometry Training in the Primary Care Setting
Spirometry is a recommended component of asthma diagnosis and treatment in the primary care setting, however, few primary care providers report routine use of spirometry in the provision of care for their asthma patients.
- Trial name
- NCT01161433
- Testing
- Virtually delivered spirometry quality improvement program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Washington
COPD
Efficacy and Safety of ICS/LABA vs. LAMA/LABA in Patients With Different COPD Phenotypes.
This is a randomized, blinded, controlled clinical trial for mexican COPD patients. Biomass smoke associated COPD (BS-COPD) clinical spectrum is different to the one seen in tobacco smoke associated COPD (TS-COPD).
- Trial name
- NCT05342558
- Testing
- Fluticasone Furoate/Vilanterol 100/25 mcgs, Umeclidinium/Vilanterol 62.5/25 mcgs
- Where
- Mexico
- Volunteers
- 133 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Asthma
Efficacy of Ciclesonide Inhaled Once Daily Versus Fluticasone Propionate Inhaled Twice Daily in Children With Asthma (4 to 15 y) (BY9010/M1-205)
The aim of the study is to compare the efficacy of ciclesonide versus fluticasone propionate on lung function, symptoms, and use of rescue medication in children with persistent asthma.
- Trial name
- NCT00163410
- Testing
- Ciclesonide
- Where
- 16 sites in India
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Asthma
Response to Albuterol Delivered Through an Anti-static Valved Holding Chamber During Nocturnal Bronchospasm
Delivery of HFA albuterol through an antistatic valved holding chamber (VHC) will improve bronchodilator response during nocturnal bronchospasm.
- Trial name
- NCT01111110
- Testing
- anti-static then static, Static then anti-static chamber
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Florida
Asthma
Study in Patients With Asthma
The purpose of this study is to determine the most safe and effective dose of the investigational drug in comparison with a control drug and placebo.
- Trial name
- NCT00215410
- Testing
- Formoterol Fumarate
- Where
- 12 sites in United States
- Volunteers
- 36 people
- Sponsor
- Dey
Asthma
To Determine the Validity of the ACT in an Adolescent Population With Persistent Asthma
To determine the measurement profiles of the asthma control test (ACT) in an adolescent population with persistent asthma.
- Trial name
- ACT2 (NCT02662413)
- Testing
- Validation of Asthma Control Questionnaire
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
Plasma Levels of MK0633 in Children Ages 6-12 (0633-023)
To evaluate the safety, tolerability and plasma levels of single oral doses of MK0633 in pediatric asthma patients ages 6 to less than 12 years.
- Trial name
- NCT00751413
- Testing
- Comparator: MK0633
- Volunteers
- 22 people
- Sponsor
- Merck Sharp & Dohme LLC
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
Asthma, Quality of Life
Evaluation of the Effectiveness and Quality of Life With the Administration of the Fixed Combination of Budesonide Formoterol in Greek Patients With Asthma During Routine Clinical Practice.
This study will be conducted in Greek population. The patients who will be selected for study enrollment will receive inhaled combination of budesonide and formoterol fumarate dihydrate at doses 100 / 6mcg, 200 / 6mcg, 400/12 mcg…
- Trial name
- BOREAS (NCT03033758)
- Testing
- Budesonide/Formoterol treated patients
- Where
- Greece
- Volunteers
- 980 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA
Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
Patients with chronic obstructive pulmonary disease (COPD) experience breathing difficulties because the airways deep in their lungs become narrowed. COPD patients use inhaler drugs to provide relief from breathlessness.
- Conditions
- CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ASTHMA, HEALTHY SUBJECTS
- Trial name
- NCT01721291
- Testing
- SALBUTAMOL
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Imperial College London
pH
The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma
The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.
- Trial name
- NCT03877874
- Testing
- Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asthma
A Study of ARRY-502 in Patients With Persistent Asthma
This is a Phase 2 study, involving a 6-week treatment period, designed to evaluate the effectiveness of investigational study drug ARRY-502 in treating mild to moderate persistent asthma, and to further evaluate the safety of the…
- Trial name
- NCT01561690
- Testing
- ARRY-502, CRTh2 antagonist; oral
- Where
- 43 sites in United States
- Volunteers
- 184 people
- Sponsor
- Pfizer
Asthma
A Patient Advocate and Literacy-Based Treatment of Asthma
Half of US adults have no more than basic reading and numerical skills. A consequence is inadequate health literacy, which is associated with unsatisfactory patient-provider communication and poor health outcomes in chronic…
- Trial name
- HAP (NCT01128348)
- Testing
- patient advocate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Asthma, Allergic Rhinitis
PF and FeNO and Clinical Characteristics in Children Being Diagnosed Due to Suspicion of Allergic Diseases
The aim of this study is to assess the influence of kind of allergic disease, allergic profile, allergen exposure, treatment method on lung function parameters, fractional exhaled nitric oxide level in children suspected and…
- Conditions
- Asthma, Allergic Rhinitis, Atopic Dermatitis, Urticaria
- Trial name
- NCT01805635
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 5,500 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Asthma
Selective β2-AR Antagonism in Asthma
The objectives are to assess the safety, tolerability and effect on the airways of TR4 in patients with mild-to-moderate asthma. The Phase 1 trial is randomised, double-blind, placebo-controlled, and ascending-dose in design.
- Trial name
- NCT07272135
- Testing
- TR4
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Trio Medicines Ltd.
Asthma
Clinical Trial on Education Method of Fluterol® Inhalation Inhaler for Asthma Control
A multi-center, randomized, open, non-inferiority, Phase 4 study
- Trial name
- NCT03110874
- Testing
- one-way education, two-way education
- Volunteers
- 184 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Obstructive Sleep Apnea
Asthma Outcomes in Children After Adenotonsillectomy
The aim of the study is to assess the effect of adenotonsillectomy on level of asthma control in preschool children with obstructive sleep apnea.
- Trial name
- NCT03842618
- Volunteers
- 60 people
- Sponsor
- Assiut University
Asthma in Children
Comparison of Combination of Beclomethasone Dipropionate and Formoterol Fumarate Versus Single Components Assessed by Knemometry and Urinary Cortisol Measurements in Asthmatic Children
single center, double-blind, double-dummy, 2-way cross over study in asthmatic children already treated with inhaled corticosteroids
- Trial name
- NCT01658891
- Testing
- combination of beclomethasone dipropionate 50µg + formoterol fumarate 6µg, free combination of beclomethasone dipropionate 100µg + Formoterol fumarate 6µg
- Where
- Denmark
- Sponsor
- Chiesi Farmaceutici S.p.A.
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