Clinical trials: BRONCHIAL ASTHMA
Asthma, Rhinitis
Oral Bacteria and Allergic Disease in Children
This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma.
- Conditions
- Asthma, Rhinitis, Eczema, Respiratory Sounds
- Trial name
- NCT00438646
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma
E-support for Healthcare Processes - ASTHMA
The purpose of the study is to establish and clinically evaluate a new approach to treating asthma by using information and communication technologies (ICT).
- Trial name
- E-ASTHMA (NCT01461642)
- Testing
- Self management asthma plan indorsment.
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Eosinophilic Granulomatosis With Polyangiitis
Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis.
The purpose of this study is to investigate, after achievement of remission, the efficacy of rituximab compared with azathioprine maintenance therapy on duration of remission, in patients with relapsing or newly-diagnosed…
- Trial name
- MAINRITSEG (NCT03164473)
- Testing
- Rituximab, Azathioprine
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma, Exercise-Induced
Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)
To determine the effect of an approved medication being studied in support of a new approach in the prevention of exercise-induced asthma (a worsening of asthma caused by exercise, also known as exercise-induced bronchospasm), in…
- Trial name
- NCT00245570
- Testing
- Comparator: Montelukast, Comparator: Salmeterol
- Volunteers
- 47 people
- Sponsor
- Organon and Co
Allergic Asthma
Predicting the Clinical Response to Omalizumab With Anti-Immunoglobulin E (IgE) Ab Response or Syk Expression in Basophils
This research is being done to test whether differences in blood cells at baseline (start of the study) can be used to predict how well omalizumab will work in a patient. Omalizumab (Xolair) is a drug approved by the U.S.
- Trial name
- NCT02023151
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN), Diarrhea
Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.
Background: Age specific mortality rate (ASMR) of 16-60 years is very high in Indian tribal areas due to communicable and non-communicable diseases.
- Conditions
- Hypertension (HTN), Diarrhea, Pneumonia, Malaria Fever
- Trial name
- MCPEPAG (NCT07436104)
- Testing
- Trained village health workers (VHWs) , provided treatment of HTN, diarrhoea, malaria, pneumonia, asthma and COPD by Amlodipine, ORS, Norfloxacin, Chloroquine, Azithromycin, salbutamol rotacaps, Appropriate referral
- Where
- India
- Volunteers
- 72,564 people, healthy volunteers welcome
- Sponsor
- MAHAN Trust
Asthma, Obesity
Teen Asthma Control Encouraging a Healthier Lifestyle
Little guidance is given to physicians caring for obese adolescents with asthma, however, findings suggest that interventions designed to achieve asthma control in these patients are necessary.
- Trial name
- TAC (NCT02575326)
- Testing
- Standard Control, a provider administered, tailored discussion guide
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Asthma in Offspring
Acid-suppressing Drugs Pregnancy Asthma Offspring Study
The purpose of this study is 1. To estimate the association between prenatal exposure to proton pump inhibitors (PPIs) and the risk of asthma during childhood. 2.
- Trial name
- NCT01787435
- Testing
- Risk of asthma in offspring
- Where
- Spain
- Volunteers
- 10,116 people
- Sponsor
- AstraZeneca
Asthma, Allergic Rhinitis
Molekule for Allergic Rhinitis/Asthma
Exposure to airborne allergens and pollutants is linked to symptom severity of allergies, asthma and other respiratory problems.
- Conditions
- Asthma, Allergic Rhinitis, Allergic Conjunctivitis
- Trial name
- NCT03627689
- Testing
- Active air purifier in respiratory allergies/asthma
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Molekule
Asthma, Lung Diseases
Genetic Epidemiology of Asthma in Costa Rica
To identify genetic factors that influence the development of asthma in Hispanics.
- Trial name
- NCT00021840
- Where
- Costa Rica
- Volunteers
- 4,245 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Eosinophilic Asthma
Phase III Long-Term Extension Study With Dexpramipexole
The goal of this clinical trial] is to evaluate the long term safety of dexpramipexole treatment in participants with severe asthma, aged ≥18 years, on Global Initiative for Asthma (GINA) 2021 [GINA, 2021] Step 4 or 5 therapy and…
- Trial name
- EXHALE-5 (NCT06388889)
- Testing
- Dexpramipexole Dihydrochloride
- Where
- 103 sites in United States, Argentina and 13 more
- Volunteers
- 509 people
- Sponsor
- Areteia Therapeutics
Childhood Asthma
Changes in the Lung Clearance Index in Pediatric Patients With Asthma
The multiple breath washout (MBW) is one of pulmonary function test that displays flow and gas concentration plotted against time, and shows an exponential decay in end-tidal gas concentration (washout curve).
- Trial name
- NCT02678949
- Testing
- Inhaled Fluticasone 50 mcg/twice day, Inhaled Fluticasone 100 mcg/twice day, Inhaled Albuterol
- Where
- Mexico
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Asthma, COPD
Assessment of Adherence to Controller Inhalation Medication in Asthma- and COPD Patients.
The main aim of the study is to evaluate the adherence to controller inhalation medication in asthma and Chronic Obstructive Pulmonary Disease (COPD) in Universitair Ziekenhuis Brussel.
- Conditions
- Asthma, COPD, Adherence, Medication
- Trial name
- NCT03791658
- Testing
- The 12-question TAI, Information from patients file, The Asthma Control Test (ACT)
- Where
- Belgium
- Volunteers
- 141 people
- Sponsor
- Universitair Ziekenhuis Brussel
Asthma
Feasibility and Acceptability of the Propeller Monitoring System in Children With Persistent Asthma
The main hypothesis of this study is to see if children and adolescents with poorly controlled asthma will find the Propeller electronic monitoring device is feasible and acceptable, and will result in improved medication…
- Trial name
- NCT03648450
- Testing
- Propeller EMD
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Connecticut Children's Medical Center
Asthma
Inhaled Steroid Treatment as Regular Therapy in Early Asthma
A study of the effect of the early treatment with Pulmicort of newly diagnosed asthma. Patients will receive either Pulmicort or a non-active treatment for three years.
- Trial name
- START (NCT00641914)
- Testing
- budesonide
- Volunteers
- 6,800 people
- Sponsor
- AstraZeneca
Asthma, Copd
Effects of Smoking on Bronchial Epithelium
Asthma and chronic obstructive pulmonary disease (COPD) are chronic inflammatory airway diseases affecting millions of people worldwide.
- Trial name
- NCT00849433
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Asthma, House Dust Mite Allergy
Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts
The purpose of this study is to investigate the safety of different doses of sublingual tablets of house dust mite allergen extracts in adults with house dust mite-associated allergic asthma.
- Trial name
- NCT01608243
- Testing
- SLIT tablets of house dust mite allergen extracts
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Stallergenes Greer
Asthma
Real World and Genomic Data Based Asthma Insight Through Network Analysis
A retrospective and prospective observational study of asthma designed to determine real-world and molecular description of asthma according to treatment and type 2 biology
- Trial name
- REGAIN (NCT06623435)
- Where
- 5 sites in United States
- Volunteers
- 1,075 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118716
- Testing
- Fluticasone propionate/salmeterol, Fluticasone Propionate
- Where
- 50 sites in United States
- Volunteers
- 248 people
- Sponsor
- GlaxoSmithKline
Severe Asthma
Severe Asthma Network Italy
The goal of this registry is collecting data of severe asthma patients, recruited by specialized centers, in a real life setting, homogeneously placed on a database management system to follow them over the time.
- Trial name
- SANI (NCT06625216)
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Società Italiana di Allergologia, Asma e Immunologia Clinica
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