Clinical trials: Back Disorder
Musculoskeletal Disorder
Performance and Safety of the PHENIX LIBERTY, a Medical Device for Electrostimulation and Biofeedback, in the Treatment of Musculoskeletal Disorders
Evaluate the evolution of locomotor abilities in patients treated with functional electrostimulation and biofeedback (PHENIX LIBERTY VIVALTIS device) for musculoskeletal disorders of the knee and spine.
- Trial name
- NCT05926739
- Testing
- Electrical stimulation and biofeedback with Phenix Liberty medical device
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Vivaltis
Lumbar Radiculopathy
Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain
To evaluate the efficacy of usage of High-voltage pulsed radiofrequency on DRG in comparison to standard-voltage pulsed radiofrequency intervention in patients with chronic lumbosacral radicular pain
- Trial name
- NCT05713032
- Testing
- Pulsed radiofrequency on lumbar dorsal root ganglion
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Alexandria University
Malocclusion, Angle Class III, Crossbite (Anterior) (Posterior)
Comparison of Two Miniscrew Anchored Maxillary Protraction Protocols
This study evaluates the dentoskeletal effects produced by two maxillary protraction protocols in adolescent patients. Half of participants will be treated with a tooth-borne and tooth-bone-borne expanders as anchorage in the…
- Trial name
- NCT03712007
- Testing
- MAMP therapy with MARPE expander, MAMP therapy with Hyrax expander
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Cataract
Posterior Assisted Levitation of Dropped Nucleus
Dropping of nucleus is a common complication during cataract extraction by phacoemulsification. The investigators describe a new technique to retrieve the dropped nucleus by using an instrument called Pars Plana Levitator…
- Trial name
- PAL (NCT00974844)
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Dow University of Health Sciences
Knee Disease, Knee Deformity
Functional Outcomes and the Restoration of Range of Motion After the Arthroscopic Complete Posterior Knee Capsulotomy in Patients With Extension Deficit of the Knee
The restriction of the range of motion is one of the most frequently encountered complications after the surgical procedures of the knee.
- Trial name
- NCT05385393
- Testing
- Arthroscopic posterior capsulotomy of the knee
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Cataract
Posterior Capsule Opacification (PCO) Evaluation of the AcrySof SN60AT Lens vs. SN60WF Lens
To assess posterior capsule opacification (PCO) in patients implanted with either the AcrySof SN60AT lens or the AcrySof SN60WF lens.
- Trial name
- NCT00762021
- Testing
- SN60AT, SN60WF
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Low Back Pain, Spondylolisthesis
Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device
Lumbar spinal fusion is commonly performed as a "last resort" in patients with chronic low back pain caused by degenerative changes and instability of the spine.
- Conditions
- Low Back Pain, Spondylolisthesis, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT00095095
- Testing
- Lumbar Interbody Fusion
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 102 people
- Sponsor
- Medtronic Spinal and Biologics
Degenerative Disk Disease
Study of Bioactive Glass-ceramic Intervertebral Spacer (Bonglass-SS) in Posterior Lumbar Interbody Fusion
The goal of this study is to compare Bonglass-SS with titanum cage.
- Trial name
- NCT01439464
- Testing
- 4 CIS one-touch titanium cage, Bonglass-SS SSLPB
- Where
- 4 sites in South Korea
- Volunteers
- 86 people
- Sponsor
- BioAlpha Inc.
Atrial Fibrillation
A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation
The purpose of this study is to assess how safe VARIPULSE catheter system is for treatment of a heart rhythm disease called persistent atrial fibrillation (PsAF) in participants who are having a catheter ablation procedure (treat…
- Trial name
- SPAA PFA (NCT07527299)
- Testing
- VARIPULSE Catheter System, LAAO Device
- Where
- 11 sites in United States
- Volunteers
- 1,070 people
- Sponsor
- Biosense Webster, Inc.
Endometriosis
Decapeptyl SR With Livial Add Back Therapy in the Management of Chronic Cyclical Pelvic Pain in Pre Menopausal Women
This is a single-centre, open-label, within patient comparison study to assess the efficacy and safety of Decapeptyl SR when administered in combination with Livial for the treatment of women with chronic cyclical pelvic pain.
- Trial name
- NCT00735852
- Testing
- Decapeptyl SR 11.25mg
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Gagging, Satisfaction, Patient
Controlling Gag Reflex During Endodontic Diagnostic Radiography
Intraoral radiography plays a vital role in endodontic diagnosis and treatment planning. However, many patients experience discomfort during periapical radiographic procedures due to factors such as a pronounced gag reflex and…
- Conditions
- Gagging, Satisfaction, Patient, Endodontic Disease, Anxiety
- Trial name
- NCT07236138
- Testing
- Periapical radiograph will be taken without VR, Periapical radiograph will be taken with VR
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qassim University
Nasopharyngeal Carcinoma, Postradiation, Necrosis, Endoscopy Surgery, Conservative Treatment
A Randomized Controlled Clinical Trial of Surgery Versus Conservative Treatment for Mild and Moderate-grade Nasopharyngeal Necrosis
Post radiation nasopharyngeal necrosis is a relatively special radiotherapy sequelae after radiotherapy for nasopharyngeal carcinoma.
- Trial name
- NCT05228093
- Testing
- Curative-intent endoscopic necrectomy followed by reconstruction using the posterior pedicle nasal septum and floor mucoperiosteum flap, Conservative treatment
- Where
- 4 sites in China
- Volunteers
- 216 people
- Sponsor
- Sun Yat-sen University
Fuchs Dystrophy, Endothelial Corneal Dystrophy
The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation
Rationale: Intra-operative optical coherence tomography (iOCT) is a new technology that incorporates advanced imaging techniques in the ophthalmic operating theatre.
- Conditions
- Fuchs Dystrophy, Endothelial Corneal Dystrophy, Bullous Keratopathy, Vision Disorders
- Trial name
- ADVISE (NCT03763721)
- Testing
- intraoperative optical coherence tomography (iOCT)
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 65 people
- Sponsor
- UMC Utrecht
Post-thoracotomy Pain
Analgesic Efficacy of SPSIP Block Versus Paravertebral Block Following Thoracotomy
Thoracotomy causes severe postoperative pain that may impair respiratory function and increase complications. This study compares the postoperative analgesic effectiveness of the serratus posterior superior intercostal plane…
- Trial name
- NCT07275047
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Thoracic Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Mitral Regurgitation
EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)
The goal of this early feasibility clinical trial is to learn if the device MR-ace Implant and Delivery System works in patients with moderate or severe mitral valve regurgitation.
- Trial name
- EXPLORE-MRace (NCT07517588)
- Testing
- MR-ace Implant and Delivery System
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Polares Medical SA
Lumbar Disc Herniation, Lumbar Discogenic Pain
Comparing General Anesthesia, General Anesthesia With ESP Block or TLIP Block in Patients Undergoing Lumbar Surgeries
The regional methods of anesthesia for the neurosurgical operations of the spine and spinal cord reducing the needs for opioids intra operatively and reducing pain in the postoperative period, decrease the numbers of failed back…
- Conditions
- Lumbar Disc Herniation, Lumbar Discogenic Pain, Lumbar Spinal Stenosis, Failed Back Surgery Syndrome
- Trial name
- NCT05447780
- Testing
- regional anesthesia
- Where
- Ukraine
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Anesthesia Research Group UA
Glottic Carcinoma, Supraglottic Carcinoma
Clinical Treatments in Specialized Diseases of Laryngeal Carcinoma (LC) and Hypopharyngeal Carcinoma (HPC)
For early stage laryngeal carcinoma and hypohparyngeal carcinoma (T1 and T2), transoral laser microsurgery, open partial laryngectomy, radiotherapy, and transoral robotic surgery were performed according to NCCN guidelines…
- Conditions
- Glottic Carcinoma, Supraglottic Carcinoma, Subglottic Carcinoma, Pyriform Sinus Carcinoma
- Trial name
- NCT04908696
- Testing
- routines
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Multiple Myeloma, Relapsed/Refractory
Testing JNJ-42756493 In Combination With Dexamethasone in Multiple Myeloma That Came Back After a Period of Improvement
This is a phase 2 study to see how effective investigational drug, JNJ-42756493, is when given in combination with dexamethasone in two groups of patients with multiple myeloma (cancer of the plasma cells, a type of white blood…
- Trial name
- NCT02952573
- Testing
- JNJ-42756493, Dexamethasone
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto