Clinical trials: Back Pain, Low
Chronic Low Back Pain, Degenerative Disc Disease
Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Opioids are frequently prescribed for chronic low back pain (CLBP). Psychiatric illness, such as high levels of depression and anxiety symptoms, is a common co-occurrence in chronic pain patients (and is termed comorbid negative…
- Conditions
- Chronic Low Back Pain, Degenerative Disc Disease, Depression, Anxiety
- Trial name
- NCT01502644
- Testing
- Oxycodone, Morphine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Brigham and Women's Hospital
Pain, Low Back Pain
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain
The purpose of this study is to determine whether BEMA Buprenorphine is safe in the treatment of chronic pain.
- Conditions
- Pain, Low Back Pain, Osteoarthritis, Neuropathic Pain
- Trial name
- NCT01298765
- Testing
- BEMA Buprenorphine
- Where
- 26 sites in United States
- Volunteers
- 302 people
- Sponsor
- BioDelivery Sciences International
Low Back Pain
Study Evaluating Dexketoprofen Trometamol/Tramadol Hydrochloride Analgesic Efficacy in Acute Low Back Pain
A randomized, double-blind, study to evaluate the analgesic efficacy and safety of Dexketoprofen trometamol and Tramadol hydrochloride combination versus placebo on moderate to severe acute pain in patients with acute low back…
- Trial name
- Dante (NCT05170841)
- Testing
- Dexketoprofen Trometamol 25 mg/Tramadol Hydrochloride 75 mg, Tramadol Hydrochloride 100 mg
- Where
- Italy
- Volunteers
- 538 people
- Sponsor
- Menarini International Operations Luxembourg SA
Back Pain Without Radiation
Duloxetine Versus Placebo in Chronic Low Back Pain
The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition--Whether duloxetine once daily can help patients with Chronic Low Back…
- Trial name
- NCT00408876
- Testing
- Duloxetine
- Where
- 4 sites in United States
- Volunteers
- 404 people
- Sponsor
- Eli Lilly and Company
Acute Low Back Pain
A Pharmacodynamic/Pharmacokinetic Study to Determine the Onset of Analgesic Effect and Plasma Levels of Tramadol in Patients With Acute Low Back Pain Receiving a Single 200 mg Dose of Tramadol Contramid® Once-a-Day
The primary objective of this study is to determine the time of onset of analgesic effect of Tramadol Contramid® Once-A-Day (OAD) in acute low back pain.
- Trial name
- NCT00952068
- Testing
- Tramadol Contramid® OAD 200mg
- Volunteers
- 47 people
- Sponsor
- Labopharm Inc.
Knee Injuries and Disorders, Ankle Injuries and Disorders
Prevention of Musculoskeletal Injuries in Slovenian Armed Forces
Physical readiness of military personnel is a cornerstone of any army, as soldiers are expected to meet high physical demands on a daily basis, and soldiers must complete one hour of physical conditioning each day.
- Conditions
- Knee Injuries and Disorders, Ankle Injuries and Disorders, Low Back Pain
- Trial name
- NCT03415464
- Testing
- Exercise
- Where
- Slovenia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Chronic Pain, Low Back Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking either WHO Step…
- Trial name
- NCT00983385
- Testing
- Tapentadol PR, Observation period
- Where
- 46 sites in Austria, Croatia and 7 more
- Volunteers
- 208 people
- Sponsor
- Grünenthal GmbH
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Low Back Pain
tDCS for Chronic Low Back Pain
The goal of this study is to investigate the role of central neural pathways in mediating chronic pain. The aim of the study is to test the effect of stimulating brain regions that are part of a network underlying central pain…
- Trial name
- NCT02771990
- Testing
- transcranial direct current stimulation
- Volunteers
- 30 people
- Sponsor
- Providence VA Medical Center
Chronic Low Back Pain
Flurbiprofen Tape for Treatment of Chronic Low Back Pain
The purpose of this trial is to evaluate the analgesic efficacy and safety of flurbiprofen tape for chronic low back pain (lasting greater than 3 months).
- Trial name
- LBP (NCT00759330)
- Testing
- Flurbiprofen Tape (Arm 2), Flurbiprofen Tape (Arm 4)
- Where
- 10 sites in United States
- Volunteers
- 127 people
- Sponsor
- Teikoku Pharma USA, Inc.
Low Back Pain
Flares of Low Back Pain With Activity Research Study
Low back pain (LBP) is the most common cause of disability worldwide. Although general activity is encouraged in the treatment of LBP, there is limited empirical information available on the specific types of activities that are…
- Trial name
- FLAReS (NCT04828330)
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- VA Office of Research and Development
Low Back Pain, Low Back Pain, Recurrent
Blue Light Device for Pain Therapy
The purpose of this study is to determine if the Pain Relief Patch, which shines light of a limited wavelength on the painful area of the back, relieves chronic musculoskeletal back pain.
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Musculoskeletal Pain, Chronic Pain
- Trial name
- PAINCT02 (NCT01528332)
- Testing
- Pain Relief Patch, Control PRP device
- Where
- 3 sites in Germany
- Volunteers
- 171 people
- Sponsor
- Philips Electronics Nederland BV
Chronic Low Back Pain
Oxycodone DETERx™ Versus Placebo in Chronic Low Back Pain (CLBP)
The purpose of this study is to evaluate the analgesic efficacy of Oxycodone DETERx compared with placebo in opioid-experienced and opioid-naive subjects with moderate-to-severe chronic low back pain requiring around-the-clock…
- Trial name
- NCT01685684
- Testing
- Oxycodone DETERx
- Where
- 45 sites in United States
- Volunteers
- 740 people
- Sponsor
- Collegium Pharmaceutical, Inc.
Chronic Low Back Pain
Reducing Sedentary Behavior to Decrease Low Back Pain: Stand Back Study
This study will test the effects of a sedentary behavior intervention on low back pain in working adults. The behavioral intervention will include the use of a sit-stand desk and a wrist-worn activity prompter that will notify…
- Trial name
- StandBack (NCT02624687)
- Testing
- Intervention, No intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoarthritis, Rheumatoid Arthritis
Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- HZ-CA-304 (NCT00613106)
- Testing
- HZT-501, Ibuprofen
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Amgen
Low Back Pain
Acupuncture Using Yamamoto's Method for the Treatment of Acute Nonspecific Low Back Pain
The aim of the present study is to assess the effectiveness of acupuncture using Yamamoto's method for the treatment of ANLBP using the following outcomes:pain,functional capacity,quality of life and number of 50 mg sodium…
- Trial name
- ANLBP (NCT01124955)
- Testing
- Acupuncture, Non-penetrating acupuncture
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of São Paulo
Back Pain Without Radiation
Duloxetine Versus Placebo in Chronic Low Back Pain
The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition.
- Trial name
- NCT00424593
- Testing
- Duloxetine
- Where
- 17 sites in Brazil, France and 3 more
- Volunteers
- 236 people
- Sponsor
- Eli Lilly and Company
Low Back Pain
EMG Activation of Gluteal Musculature During Exercises With and Without Resistance
The gluteus medius (Gmed) and gluteus maximus (Gmax) muscles are important components in the treatment of many lower limb injuries.
- Trial name
- GlutEMG02 (NCT01841216)
- Testing
- Lower Body Exercises with and without resistance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Cannabis, Low Back Pain
Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain
This study will involve treating low back pain associated with nerve injury with oral delta-9-tetrahydrocannabinol (Δ9-THC) or whole plant cannabis for eight weeks.
- Conditions
- Cannabis, Low Back Pain, Neuropathic Pain
- Trial name
- NCT02460692
- Testing
- dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of California, San Diego
Low Back Pain
Trial of Scrambler Therapy or Sham Treatment for Low Back Pain
This pilot study will evaluate Scrambler therapy and Sham treatment on levels of low back pain, pain sensitivity and mRNA expression of pain sensitivity candidate genes.
- Trial name
- NCT01896687
- Testing
- Scrambler
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Virginia Commonwealth University