Clinical trials: Back Pain Lower Back
Sciatica, Radiculopathy
Steroids Versus Gabapentin
The purpose of this study is to determine whether pharmacotherapy or epidural steroid injections are a better treatment for lumbosacral radicular pain.
- Trial name
- NCT01495923
- Testing
- epidural steroid injection, Gabapentin
- Where
- 3 sites in United States
- Volunteers
- 145 people
- Sponsor
- Johns Hopkins University
Chronic Low Back Pain
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
The primary purpose of the study was to test the efficacy of 2 tablets (twice daily) of ABT-712, compared to placebo, administered over a 4-week period in participants with moderate to severe mechanical chronic low back pain…
- Trial name
- NCT00761150
- Testing
- ABT-712
- Where
- 32 sites in United States
- Volunteers
- 308 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Spinal Stenosis, Low Back Pain
Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)
The broad, long-term objective of this research protocol is to improve the quality of life for patients suffering from lumbar spinal stenosis.
- Trial name
- LESS (NCT01238536)
- Testing
- Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection
- Where
- 10 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Washington
Low Back Pain
Effects of Metformin on Low Back Pain
The purpose of the current study is to determine the effects of metformin in non-diabetic patients with low back pain, and identify novel targets for future treatments
- Trial name
- NCT04055012
- Testing
- Metformin
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Gwendolyn Sowa
Chronic Low Back Pain
Reducing Sedentary Behavior to Decrease Low Back Pain: Stand Back Study
This study will test the effects of a sedentary behavior intervention on low back pain in working adults. The behavioral intervention will include the use of a sit-stand desk and a wrist-worn activity prompter that will notify…
- Trial name
- StandBack (NCT02624687)
- Testing
- Intervention, No intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Low Back Pain
Auricular Vagus Nerve Stimulation for Chronic Pain
This proposal aims to investigate the treatment effect and underlying mechanism of transcutaneous acupuncture stimulation on chronic low back pain.
- Trial name
- NCT03959111
- Testing
- Stimulation at Location 1, Stimulation at Location 2
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Low Back Pain
Effects of Programming Parameters on Back Pain Relief in Subthreshold Spinal Cord Stimulation
The purpose of this study is to investigate the effects of varying programming parameters in subthreshold spinal cord stimulation therapy for pain relief.
- Trial name
- NCT01550562
- Testing
- Boston Scientific Precision Plus spinal cord stimulation therapy
- Where
- Australia
- Volunteers
- 1 people
- Sponsor
- Boston Scientific Corporation
Back Pain Lower Back
Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Our clinical trial has the purpose to evaluate the effectiveness in reducing pain and improving function and quality of life during a 6-months follow-up of a therapeutic exercise program compared to pharmacological treatment with…
- Trial name
- DLSEA (NCT01374269)
- Testing
- Exercise program, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Grupo Rehabilitacion en Salud
Rheumatic Diseases, Arthralgia
PASCOE-Agil HOM-Injektopas in the Treatment of Rheumatic Disorders
The purpose of this observational study is to give an overview of the use of PASCOE-Agil HOM-Injektopas in a 2-4 week treatment of rheumatic disorders.
- Conditions
- Rheumatic Diseases, Arthralgia, Myalgias/Myopathy, Lumbago
- Trial name
- 157 (NCT00922428)
- Volunteers
- 1,389 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Low Back Pain
Effects and Mechanisms of Specific Trunk Exercises in Low Back Pain
Low back pain affects 80% of Americans at some time during their lives. Although recovery usually occurs within 6 months, there is a 50% recurrence within one year's time.
- Trial name
- NCT01611792
- Testing
- Stabilization exercise protocol, Strength and conditioning exercise protocol
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Low Back Pain
The McKenzie Method Versus Manipulation for Patients With Chronic Low Back Pain
Introduction: The McKenzie method as well as spinal manipulation is commonly used for the treatment of low back pain throughout the western world.
- Trial name
- NCT00939107
- Testing
- spinal manipulation, McKenzie exercises
- Where
- Denmark
- Volunteers
- 350 people
- Sponsor
- Back and Rehabilitation Center, Copenhagen
Osteoarthritis, Low Back Pain
Study of COV795 in Subjects With Osteoarthritis or Chronic Low Back Pain
The primary objective is to demonstrate the safety and tolerability of COV795 with up to 35 days use as evaluated by physical exam, vital signs, pulse oximetry, clinical laboratory tests, and other adverse events (AEs).
- Trial name
- NCT01451385
- Testing
- COV795
- Where
- 42 sites in United States
- Volunteers
- 376 people
- Sponsor
- Mallinckrodt
Low Back Pain, Pain
Care Management for the Effective Use of Opioids
The CAre Management for the Effective use of Opioids (CAMEO) trial is a 2-arm randomized clinical trial to compare the effectiveness of pharmacological vs. behavioral approaches for chronic lower back pain.
- Trial name
- CAMEO (NCT01236521)
- Testing
- Pharmacological (MED), Behavioral treatment (CBT)
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- VA Office of Research and Development
Low Back Pain
Patient Response to Spinal Manipulation
This is a biomechanical study which is Project 1 in the Developmental Center for Clinical and Translational Research in Chiropractic (DCRC I) (NIH/NCCAM grant 1 U19 AT004663-01; principal investigator Christine Goertz, DC, PhD).
- Trial name
- PRiSM (NCT01670292)
- Testing
- HVLA-SM
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic
Subacute Low Back Pain
Subacute Low Back Pain in Active Duty
The overall objective of this project is to compare three home-managed treatment regimens for subacute low back pain: Progressive Exercise Plan (PEP), NMES (neuromuscular electrical stimulation) core strength training and…
- Trial name
- LBP (NCT03502187)
- Testing
- Progressive Exercise Plan, NeuromuscularElectricalStimulation(NMES), Primary Care Management (PCM)
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Chronic Low Back Pain, Opioid Use, Unspecified
The Effects of Cognitive Behavioral Therapy and Transcranial Current Stimulation (tDCS) on Chronic Lower Back Pain
The primary objective of this study is to evaluate the effects of cognitive-behavioral therapy in combination with transcranial direct current stimulation in (1) improving pain and functionality, (2) reducing severity of opioid…
- Trial name
- NCT02483468
- Testing
- Cognitive Behavioral Therapy for Pain, Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Medical University of South Carolina
Chronic Pain
Study of PM Modulation Therapy in Trial Phase
Trialing of PM modulation therapy in patients with chronic intractable low back pain
- Trial name
- NCT03110601
- Testing
- Control - Conventional SCS, Test - Stimgenics SCS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stimgenics LLC
Chronic Low Back Pain
Flurbiprofen Tape for Treatment of Chronic Low Back Pain
The purpose of this trial is to evaluate the analgesic efficacy and safety of flurbiprofen tape for chronic low back pain (lasting greater than 3 months).
- Trial name
- LBP (NCT00759330)
- Testing
- Flurbiprofen Tape (Arm 2), Flurbiprofen Tape (Arm 4)
- Where
- 10 sites in United States
- Volunteers
- 127 people
- Sponsor
- Teikoku Pharma USA, Inc.
Low Back Pain
A Prospective Pilot Study Investigating the Impact of ThermaCare on Flexibility, Muscle Relaxation & Low Back Pain
The objective of this Investigator Initiated study is to evaluate the effectiveness of ThermaCare HeatWraps in improving flexibility and low back muscle relaxation, and in participants experiencing pain, reducing pain during…
- Trial name
- NCT03151265
- Testing
- ThermaCare Low Back Heat Wrap
- Where
- 3 sites in Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- dorsaVi Ltd
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware