Clinical trials: Back Pain Lower Back
Low Back Pain
Biomechanics of Lumbar Region in Low Back Pain
The purpose of this study was to examine the relationship between non-specific low back pain (NSLBP) and lumbar lordosis angle (LLA) and lumbar muscle thickness (LMT) by evaluating magnetic resonance images (MRI) in individuals…
- Trial name
- NCT05095402
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Karabuk University
Acute Low Back Pain, Physical Activity
Acute Low Back Pain: Causes, Mechanisms, Treatment and Followup
The purpose of this study is to investigate acute low back pain, its origin, mechanisms, the cause of pain, evaluation of treatments and development.
- Trial name
- ALBP (NCT02517762)
- Testing
- Physical activity
- Volunteers
- 99 people
- Sponsor
- Göteborg University
Chronic Low Back Pain
Pulsed Shortwave Therapy Treatment for Chronic Musculoskeletal Low Back Pain
The ActiPatch is a cutaneous device which is CE marked approved for relief of pain and has FDA clearance as an over the counter device for the adjunctive treatment of osteoarthritis of the knee and plantar fasciitis.
- Trial name
- PSWT (NCT03240146)
- Testing
- Pulsed Shortwave Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- BioElectronics Corporation
Chronic Low Back Pain
Optimizing Chronic Pain Management Through Patient Engagement With Quality of Life Measures
This study evaluates the use of a health-related quality of life report based on the SPADE cluster (sleep disturbance, pain interference with activities, anxiety, depression, and low energy/fatigue) derived from the PROMIS-29…
- Trial name
- OPTIQUAL (NCT04168437)
- Testing
- Health-Related Quality of Life Report
- Where
- United States
- Volunteers
- 331 people
- Sponsor
- University of North Texas Health Science Center
Low Back Pain
DIAM™ Spinal Stabilization System Long Term Follow up Clinical Plan
A hybrid prospective/retrospective, multicenter, single-arm, data collection study.
- Trial name
- NCT05201573
- Testing
- Observational
- Volunteers
- 175 people
- Sponsor
- Companion Spine, LLC
Chronic Low Back Pain
A Pilot Study Examining the Efficacy of Biomodulator Treatment for Chronic Low Back Pain
The purpose of this study is to determine the efficacy of self treatment with the Biomodulator device to decrease chronic low back pain (LBP) in active duty service members.
- Trial name
- NCT02707094
- Testing
- Biomodulator, Usual Care (Medication + Exercise)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brooke Army Medical Center
Chronic Low Back Pain, Chronic Leg Pain
Comparison of the Effects of Two Spinal Cord Stimulation (SCS) Therapies on Subject Reported Pain (BENEFIT-02)
A BIOTRONIK wearable stimulator will be utilized in order to investigate the effects of two study spinal cord stimulation (SCS) therapies on subject reported pain and paresthesia perception observed over 12 days of study…
- Trial name
- NCT03594266
- Testing
- Therapy A spinal cord stimulation parameter set using BIO-RNA system and associated components, Therapy B spinal cord stimulation parameter set using BIO-RNA system and associated components
- Where
- 18 sites in United States
- Volunteers
- 136 people
- Sponsor
- Biotronik, Inc.
Osteoarthritis, Back Pain
A Study to Compare Oxycodone/Naloxone Prolonged Release Against Codeine/Paracetamol in the Treatment of Moderate to Severe Chronic Low Back Pain or Pain Due to Osteoarthritis
The purpose of this study is to compare oxycodone/naloxone combination tablet and codeine/paracetamol tablets in the treatment of moderate to severe chronic low back pain or pain due to osteoarthritis.
- Trial name
- NCT00784810
- Testing
- Oxycodone/Naloxone, Codeine/Paracetamol
- Where
- United Kingdom
- Volunteers
- 247 people
- Sponsor
- Napp Pharmaceuticals Limited
Intervertebral Disc Degeneration, Chronic Low-back Pain
Efficacy of Intradiscal Injection of Autologous BM-MSC in Worker Patients Affected by Chronic LBP Due to Multilevel IDD
ACTIVE is a phase II B efficacy monocenter, prospective, randomized, controlled double blinded trial, in which intra-discal autologous adult BM-MSC therapy will be compared with sham treated controls.
- Trial name
- ACTIVE (NCT04759105)
- Testing
- Autologous BM-MSC
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
CLBP - Chronic Low Back Pain
Effect Virtual Reality Fully Immersive Based Exercise Game on Reducing Fear of Movement in People With CLBP
Low back pain is one of the most common problems among adults and a leading cause of disability worldwide including in Saudi Arabia (Buchbinder et al., 2018) (Awaji, 2016) .
- Trial name
- NCT05267756
- Testing
- (kurki-application),VR glasses
- Where
- Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- King Saud University
Low Back Pain
McKenzie Protocol With/Without Postural Control Exercises on Pain, ROM, and Disability in Low Back Pain
Chronic Low Back Pain (CLBP) is a prevalent global musculoskeletal disorder associated with significant physical, psychosocial, and economic burdens.
- Trial name
- NCT06796465
- Testing
- McKenzie with Progressive Postural Control Exercises, McKenzie without Progressive Postural Control Exercises, Hot Pack
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Low Back Pain
Fatty Infiltration in Paraspinal Muscles and Lumbar Erector Spina Plane Block
This study aimed to investigate the relationship between fatty infiltration in the lumbar paraspinal (multifidus and erector spinae) muscles, clinical characteristics, and treatment response after lumbar erector spinae plane…
- Trial name
- NCT06208865
- Testing
- lumbar erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Diskapi Teaching and Research Hospital
Back Pain
Safety and Efficacy of the TransDiscal System Versus Medical Management in Treating Chronic Discogenic Low Back Pain
The primary objective of this randomized controlled trial is to evaluate the safety and efficacy of the TransDiscal System (TDS) in treating discogenic pain of the lumbar spine using a modified disc biacuplasty procedure.
- Trial name
- COLD (NCT01263054)
- Testing
- TransDiscal System, Medical Management
- Where
- 9 sites in United States
- Volunteers
- 67 people
- Sponsor
- Halyard Health
Persistent Non Specific Low Back Pain
Wet Cupping in Non-specific Low Back Pain
Background: Persistent nonspecific low back pain (PNSLBP) is one of the most common low back pains worldwide. Many interventions were tried including wet cupping which is commonly used for pain conditions in Saudi Arabia and…
- Trial name
- NCT02012205
- Testing
- wet cupping
- Where
- 3 sites in Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- National Center for Complementary and Alternative Medicine, Saudi Arabia
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
Chronic Low Back Pain, Diabetic Peripheral Neuropathy
MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain
This study is designed to assess: Hypothesis #1: That there is a significant central pain component in a distinct subset of patients diagnosed with knee osteoarthritis(KOA), Chronic low back pain(CLBP), painful diabetic…
- Conditions
- Chronic Low Back Pain, Diabetic Peripheral Neuropathy, Knee Osteoarthritis
- Trial name
- NCT01620775
- Testing
- MRIs, Pain testing
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Non-specific Low Back Pain
Prevalence Of Disability And Fear Avoidance Beliefs
Three hundred eighty -one egyptian physical therapists of both genders with age 25-55 years old in Cairo governorate who have worked for at least two years.The study will be conducted to investigate the prevalence of disability…
- Trial name
- NCT07286630
- Testing
- Fear avoidance beliefs questionnaire
- Where
- Egypt
- Volunteers
- 381 people
- Sponsor
- Dina Abdelhady Hammad Attia Ahmed
Back Pain
Pilot Evaluation to Assess the Clinical and Economic Impact of Pfizer's Pain Management Program (painPREMIER) in the Treatment of Low Back Pain, in an Occupational Health Care Setting in Finland
The aim of this investigation is to determine whether the use of painPREMIER will significantly improve function in patients with low back pain in an occupational health clinical setting.
- Trial name
- NCT01787565
- Testing
- painPREMIER cohort, Control cohort
- Where
- Finland
- Volunteers
- 86 people
- Sponsor
- Pfizer
Low Back Pain
Back Pain Outcomes Using Longitudinal Data (BOLD)
The overall objective of BOLD is to establish a large, community-based registry (at least 5000 subjects) of patients aged 65 years and older presenting with new episodes of healthcare visits for back pain.
- Trial name
- BOLD (NCT01776242)
- Where
- 3 sites in United States
- Volunteers
- 5,239 people
- Sponsor
- University of Washington
Lordosis, Low Back Pain
Effects of Muscle Energy Technique and Postural Correction Exercises in Lordotic Females Wearing High Heels
The key purpose was to determine the effects of Muscle Energy Technique (MET) and Postural Correction Exercises on low back pain in females wearing high heels.
- Trial name
- NCT05015205
- Testing
- Muscle Energy Technique, Postural Correction Exercises
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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