Clinical trials: Back Pain Lower Back
Trust, Chronic Low Back Pain
Correlation of Trust and Outcomes Following Physical Therapy for Chronic Low Back Pain
To investigate whether changes in trust between physical therapist and patient correlate to outcomes after receiving physical therapy care.
- Conditions
- Trust, Chronic Low Back Pain, Physical Therapy
- Trial name
- NCT03443401
- Testing
- Standard physical therapy care
- Where
- 11 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of South Dakota
Osteoarthritis, Low Back Pain
An Efficacy and Safety Study of Fentanyl Transdermal Patch in Filipino Participants With Osteoarthritis and Chronic Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of fentanyl among Filipino participants with osteoarthritis (disorder which is seen mostly in older persons in which the joints become painful and stiff) and…
- Trial name
- NCT01795898
- Testing
- Fentanyl
- Where
- Philippines
- Volunteers
- 237 people
- Sponsor
- Janssen Pharmaceutica
Chronic Low Back Pain
Strategies to Assist With Management of Pain
Chronic low back pain (CLBP) has no known effective treatment. While often treated with long-term opioid therapy, opioids do not work well for many patients and can cause serious side effects, including addiction, poorer mental…
- Trial name
- STAMP (NCT03115359)
- Testing
- Mindfulness Based Therapy, Cognitive Behavioral Therapy
- Where
- 4 sites in United States
- Volunteers
- 770 people
- Sponsor
- University of Wisconsin, Madison
Failed Back Surgery Syndrome, Complex Regional Pain Syndrome (CRPS)
A Study to Confirm the Safety of High Frequency DRG Stimulator in Patients With Chronic Lower Limb Pain
This study is a prospective, single-arm, open label, single center pilot study to confirm the safety of a ultrahigh frequency DRG stimulator in patients with chronic lower limb pain. The actual trial length is 5 days.
- Trial name
- NCT03285113
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- GiMer Medical
Low Back Pain
Postoperative Opioid Use and Pain Scores in Patients Undergoing Transforaminal Lumbar Interbody Fusion
The purpose of this project is to study the effects of preoperative followed by scheduled intravenous acetaminophen on pain control for 24 hours postoperatively after minimally invasive 1 or 2 level transforaminal lumbar…
- Trial name
- NCT02061774
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Chronic Low Back Pain
Interactive Voice Response (IVR)-Based Treatment for Chronic Low Back Pain
The proposed study will test how well an innovative method, interactive voice response (IVR), can be used for delivering an treatment for chronic low back pain.
- Trial name
- NCT01025752
- Testing
- Face to face cognitive behavior therapy, IVR based cognitive behavioral therapy
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- VA Office of Research and Development
Chronic Low-Back Pain, Refractory Pain
Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
The objective of this study is to evaluate the efficacy of BurstDR dorsal column stimulation, compared with conventional medical management, in improving pain and back-related physical function in subjects suffering with chronic…
- Conditions
- Chronic Low-Back Pain, Refractory Pain, Neuropathic Pain
- Trial name
- NCT04479787
- Testing
- Spinal Cord Stimulation, Conventional Medical Management
- Where
- 30 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Devices
Low Back Pain
Mechanisms of Specific Trunk Exercises in Low Back Pain
The research objective is to determine which physical therapy (PT) treatment is the most efficacious for patients with lower back pain (LBP), who have been subgrouped based on certain clinical features.
- Trial name
- NCT01362049
- Testing
- Physical Therapy rehabilitation: Stabilization exercises., Physical Therapy rehabilitation. Movement System Impairment (MSI) classification based exercise
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Vermont
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Lumbar Radiculopathy
Safety and Efficacy of SX600 Administered by Lumbosacral Transforaminal Epidural Injection for Radicular Pain
This is a Phase I/II, double-blind, parallel-group, randomized, placebo-controlled multi-centre trial in 180 patients randomized 1:1:1 to receive the IMP (Dexamethasone acetate microspheres for extended-release injectable…
- Trial name
- SALIENT (NCT03952377)
- Testing
- SX600
- Where
- 10 sites in Australia
- Volunteers
- 56 people
- Sponsor
- SpineThera Australia PTY LTD
Low Back Pain
Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Chronic Low Back Pain
The objective of this study is to determine the analgesic efficacy and safety of Buprenorphine Transdermal System (BTDS) 10 and 20 compared to placebo in opioid-naïve subjects with moderate to severe chronic low back pain.
- Trial name
- NCT00490919
- Testing
- Buprenorphine transdermal system
- Where
- 86 sites in United States
- Volunteers
- 539 people
- Sponsor
- Purdue Pharma LP
Low Back Pain
Comparison of Extensible and Inextensible Lumbosacral Orthoses for Lower Back Pain
This study is designed to discern if the use of a lumbosacral orthesis (LSO, also call a back support) improves the short-term outcome of lower back pain.
- Trial name
- LSO LBP (NCT01933399)
- Testing
- Inextensible LSO (stiff back support), Extensible LSO, a back support that is flexible, Standard of Care
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Medical University of South Carolina
Low Back Pain
The Use of Methylsulfonylmethane (MSM) in the Treatment of Low Back Pain
The investigators are studying whether MSM plus standard of care naproxen improves symptoms of lower back pain compared to standard of care naproxen plus placebo. Subjects will be randomized into 1 of 2 groups.
- Trial name
- NCT02268305
- Testing
- MSM 1000mg twice a day (6000 mgs)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mike O'Callaghan Military Hospital
Chronic Low-back Pain
Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain
Testing the effect of Virtual Reality - guided imagery acupuncture
- Trial name
- NCT06814470
- Testing
- Virtual reality guided imagery acupuncture treatment (VRGAIT), Virtual reality guided imagery acupuncture treatment control
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Low Back Pain
High Level Pulsed Heat Versus Low Level Steady Heat in Subjects With Chronic Low Back Pain
This study is a double blinded randomized active placebo controlled trial in subjects with chronic low back pain. The trial compares pain relief by a device that delivered high level pulsed heat (45 °C) to pain relief delivered…
- Conditions
- Chronic Pain, Low Back Pain, Heat, Analgesia
- Trial name
- NCT04109703
- Testing
- High Level Pulsed Heat delivered by Generation 5 devices from Soovu Labs Inc., Low Level (37 degrees C) delivered by the control device Generation 5 devices from Soovu Labs Inc.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Low Back Pain
Acute Low Back Pain. Topical Diclofenac and Oral Ibuprofen.
This is a randomized, double-blind placebo-controlled study comparing two different treatments for acute low back pain: oral ibuprofen and topical diclofenac.
- Trial name
- NCT04611529
- Testing
- Ibuprofen 400 mg, Topical diclofenac
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Montefiore Medical Center
Pain, Chronic Pain
Effect of Pulse Width With Spinal Cord Stimulation
The primary objective of this study is to assess the effects of varying pulse width in suprathreshold dorsal column stimulation in patients with low back pain.
- Conditions
- Pain, Chronic Pain, Back Pain
- Trial name
- NCT00399516
- Testing
- Precision
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston Scientific Corporation
Low Back Pain
Effect of Milnacipran in Chronic Neuropathic Low Back Pain
Low back pain is a public health problem affecting between 70-85% of adults at some time in their life. This study is being done to study the safety and effectiveness of the drug Milnacipran in treating chronic low back pain.
- Trial name
- NCT01225068
- Testing
- Milnacipran
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwestern University
Musculoskeletal Pain
Effects of Osteopathic Manipulative Treatment and Bio Electro-Magnetic Regulation Therapy on Low Back Pain in Adults.
It is clear that low back pain (LBP) is a major challenge in our society, which can lead to severe disability in many individuals.
- Trial name
- NCT04704375
- Testing
- Bio Electro-Magnetic Regulation (BEMER) Therapy, OMT (osteopathic manipulative treatment), Light touch
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lake Erie College of Osteopathic Medicine
Pain, Back Pain
Development of STEPPT
This 6-month pilot study aims to assess the feasibility, acceptability, and estimate effect sizes of the pilot STEPPT intervention for addressing ethnic disparities in physical therapy referrals and adherence between Hispanic and…
- Conditions
- Pain, Back Pain, Low Back Pain, Chronic Pain
- Trial name
- STEPPT PILOT (NCT06835439)
- Testing
- STEPPT Pilot, Standard Care (Control)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- San Diego State University