Clinical trials: Back Pain Lower Back
Low Back Pain
Flares of Low Back Pain With Activity Research Study
Low back pain (LBP) is the most common cause of disability worldwide. Although general activity is encouraged in the treatment of LBP, there is limited empirical information available on the specific types of activities that are…
- Trial name
- FLAReS (NCT04828330)
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- VA Office of Research and Development
Chronic Low-back Pain, Chronic Pain
Digital Clinical Hypnosis for Chronic Pain Management
This ClinicalTrials.gov posting contains two randomized controlled trials. The study procedures were identical, except Study 1 was funded by NIH and enrolled adults with chronic low back pain, whereas Study 2 was funded by the UW…
- Trial name
- NCT06050083
- Testing
- Hypnosis audio recordings
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Chronic Lower Back Pain, Chronic Pain
Buprenorphine (CAM2038) in Subjects With a Recent History of Moderate to Severe Chronic Low Back Pain
This is a Phase III, placebo-controlled, multicenter study with an enriched-enrollment withdrawal (EEW) design to evaluate the efficacy and safety of CAM2038 in opioid-experienced subjects with moderate to severe CLBP that…
- Trial name
- CAM2038 (NCT02946073)
- Testing
- buprenorphine
- Where
- 69 sites in United States
- Volunteers
- 1,053 people
- Sponsor
- Braeburn Pharmaceuticals
Low Back Pain
Long Term Safety Study of Tanezumab in Chronic Low Back Pain
The purpose of this study is to investigate the safety and efficacy of tanezumab for chronic low back pain. Patients who were randomized and treated with study medication in a previous chronic low back pain "parent" study will be…
- Trial name
- NCT00924664
- Testing
- Tanezumab 20 mg, Tanezumab 10 mg
- Where
- 149 sites in United States
- Volunteers
- 849 people
- Sponsor
- Pfizer
Recurrent Low Back Pain
Mixed Reality Gaming for Chronic Low Back Pain
Mixed Reality Gaming for Chronic Low Back Pain
- Trial name
- NCT03603028
- Testing
- Exergaming
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Alabama at Birmingham
Chronic Low Back Pain
Orthotic Use for Chronic Low Back Pain
The purpose of this research study is to determine the change in perceived levels of pain and dysfunction in 50 patients with chronic low back pain, following the use of custom-made shoe orthotics for a three month period.
- Trial name
- NCT00976664
- Testing
- Shoe orthotic, Shoe Orthotic Wait Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National University of Health Sciences
Pain
Chronic Low Back Pain and Meditation
The purpose of this research study is to see if and how mindfulness meditation affects pain. Specifically, we are interested in assessing if mindfulness is associated with the release of naturally occurring opiates in the body…
- Trial name
- NCT04034004
- Testing
- Mindfulness, Naloxone, Saline
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- University of California, San Diego
Low Back Pain
Ibuprofen With or Without Acetaminophen for Low Back Pain
This is a randomized clinical trial comparing two interventions for acute low back pain: 1. Ibuprofen + acetaminophen 2. Ibuprofen + placebo Participants will include patients who present to an emergency room for management of…
- Trial name
- NCT03554018
- Testing
- Acetaminophen, Ibuprofen 600 mg, Educational intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Montefiore Medical Center
Low Back Pain
Pilot Study to Evaluate The Effectiveness And Safety Of Axiom Worldwide Drx9000™ Spinal Decompression System
This pilot study will evaluate the effectiveness and safety of the Axiom Worldwide DRX9000 for active treatment of chronic low back pain.
- Trial name
- NCT00414596
- Testing
- DRX9000™
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- NEMA Research, Inc.
Chronic Low Back Pain
Study to Test the Effectiveness of Controlled-Release OROS® Hydromorphone HCl Compared to Placebo in Patients With Chronic Low Back Pain
This study will test an experimental drug called OROS® hydromorphone hydrochloride (HCl) (NMED-1077), a once daily opioid analgesic that can relieve pain. A large number of clinical studies have been conducted to test this drug.
- Trial name
- NCT00549042
- Testing
- OROS hydromorphone
- Volunteers
- 459 people
- Sponsor
- Mallinckrodt
Spinal Stenosis
Clinical Trial Comparing Decompression With and Without Coflex™ Interlaminar Technology Treating Lumbar Spinal Stenosis
A 2 year comparative evaluation of clinical outcome in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with and without additional stabilization using the coflex® Interlaminar…
- Trial name
- NCT01316211
- Testing
- Implantation of coflex™ after surgical decompression, Surgical decompression
- Where
- 8 sites in Germany
- Volunteers
- 246 people
- Sponsor
- Paradigm Spine
Low Back Pain
Collaborative Care for Older Adults With Back Pain (COCOA)
The purpose of the Collaborative Care for Older Adults with Back Pain (COCOA) Clinical Trial is to evaluate the clinical effectiveness and feasibility of a collaborative care model (medical and chiropractic care) through a…
- Trial name
- COCOA (NCT01312233)
- Testing
- Medical Care, Dual Care, Shared Care
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Palmer College of Chiropractic
Lower Back Pain
Treatment of Back Pain Using Transcutaneous Magnetic Stimulation (TCMS)
This is a single-site, randomized, Single-blinded, placebo-controlled, trial of Transcutaneous Magnetic Stimulation (TCMS) for the treatment of lower back pain.
- Trial name
- NCT02421757
- Testing
- Fischell Transcutaneous Magnetic Stimulation Pain Treatment Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Low Back Pain
Efficacy of the Quell Wearable Device for Chronic Low Back Pain
This is a 1-year trial designed to gather information about the use of the Quell for persons with chronic musculoskeletal low back pain.
- Trial name
- NCT02944513
- Testing
- Quell
- Volunteers
- 68 people
- Sponsor
- Brigham and Women's Hospital
Back Pain Without Radiation
Duloxetine Versus Placebo in Chronic Low Back Pain
The primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition--Whether duloxetine once daily can help patients with Chronic Low Back…
- Trial name
- NCT00408876
- Testing
- Duloxetine
- Where
- 4 sites in United States
- Volunteers
- 404 people
- Sponsor
- Eli Lilly and Company
Low Back Pain
Brain Imaging of Lidoderm for Chronic Back Pain
The investigators tested whether pain decrease can be observed centrally with non-invasive brain imaging in CBP subjects receiving Lidoderm. The investigators first tested effects of 5% Lidoderm patched in an open labelled trial.
- Trial name
- NCT01515540
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Low Back Pain
Long Term Safety and Efficacy Study of Tanezumab in Japanese Adult Subjects With Chronic Low Back Pain
This study will investigate the long-term safety and efficacy of a fixed dose of tanezumab 5 mg and 10 mg administered subcutaneously (SC) seven times at 8 week intervals.
- Trial name
- TANGO (NCT02725411)
- Testing
- Celecoxib, Tanezumab 5 mg, Tanezumab 10 mg
- Where
- 55 sites in Japan
- Volunteers
- 277 people
- Sponsor
- Pfizer
Low Back Pain
Exercise for Low Back Pain in Children
This study aimed to determine the efficacy of an eight-week specific exercise programme in reducing self-reported episodes and intensity of LBP, as well as modifying some of the identified risk factors for LBP, in children.
- Trial name
- LBP (NCT00786864)
- Testing
- exercise programme
- Where
- South Africa
- Volunteers
- 72 people
- Sponsor
- University of Witwatersrand, South Africa
Knee Injuries and Disorders, Ankle Injuries and Disorders
Prevention of Musculoskeletal Injuries in Slovenian Armed Forces
Physical readiness of military personnel is a cornerstone of any army, as soldiers are expected to meet high physical demands on a daily basis, and soldiers must complete one hour of physical conditioning each day.
- Conditions
- Knee Injuries and Disorders, Ankle Injuries and Disorders, Low Back Pain
- Trial name
- NCT03415464
- Testing
- Exercise
- Where
- Slovenia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Chronic Low-back Pain
Development and Feasibility of Mindfulness Based Pain Reduction
This is a development study with clinical outcomes. The investigators aim to develop and test an 8-week MBPR (Mindfulness-Based Pain Reduction) program, which draws on intervention work and clinical experience in the…
- Trial name
- MBPR (NCT04980612)
- Testing
- Mindfulness Based Pain Reduction, Mindfulness Based Stress Reduction
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Francisco