Clinical trials: Back Pain Lower Back Chronic, active
Chronic Non-Specific Low Back Pain, Chronic Non-specific Neck Pain
Predictive Variables of Outcome in Subjects With Chronic Rachialgia Referred to Different Pathways of Physiotherapy.
The aim of this study is to investigate the predictive value of various biopsychosocial variables on the outcomes of subjects with chronic spinal pain undergoing public health rehabilitation pathways.
- Trial name
- PRE-CBP (NCT06915896)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Chronic Low Back Pain, After Lumbar Spine Surgery
Efficacy of Cognitive Functional Therapy in Individuals With Chronic Low Back Pain After Spinal Surgery
Chronic low back pain after spinal surgery is a complex and disabling condition influenced by biopsychosocial factors. Cognitive Functional Therapy (CFT) is a promising intervention targeting these multidimensional aspects.
- Conditions
- Chronic Low Back Pain, After Lumbar Spine Surgery, Failed Back Surgery Syndrome (FBSS)
- Trial name
- NCT07576062
- Testing
- CFT
- Volunteers
- 90 people
- Sponsor
- Centro Universitário Augusto Motta
Overweight or Obesity, Chronic Low-back Pain
Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Chronic low back pain (CLBP) is the most expensive cause of workrelated disability: it causes the highest number of years lived with disability.
- Trial name
- BO2WL (NCT05811624)
- Testing
- Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy., Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
- Where
- 2 sites in Belgium, Switzerland
- Volunteers
- 252 people
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain, Chronic Low Back Pain
Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome
The aim of the study is to evaluate the effects of biofeedback-assisted stabilization training and conventional therapy on pain perception, balance, spinal mobility, functional performance, physical activity, stress level, and…
- Trial name
- NCT07463729
- Testing
- Standard Rehabilitation, Biofeedback Ultrasonography
- Where
- Poland
- Volunteers
- 110 people
- Sponsor
- University of Rzeszow
Chronic Sacroiliac Joint Pain
Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain
This is a single-center, randomized, open-label, pilot study in adult subjects with chronic sacroiliac joint (SIJ) pain. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº…
- Trial name
- NCT06935539
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Chronic Low-back Pain
Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain
Low back pain (LBP) is the leading cause of disability worldwide. Currently available treatment options for treating low back facet joint pain include acupuncture, pain medications, psychotherapy, anti-inflammatory steroid…
- Trial name
- NCT06804551
- Testing
- iovera system, Radiofrequency ablation alone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Low Back Pain, Chronic Low-back Pain (cLBP)
Virtual Tai Chi for Chronic Low Back Pain (Spine 2027)
This study tests whether a virtually delivered integrated tai chi, qigong, and meditation program, added to usual care, improves chronic low back pain, disability, quality of life, and healthcare costs compared with usual care…
- Trial name
- NCT07772154
- Testing
- Virtually Delivered Integrated Tai Chi, Qigong, and Meditation (VDTQM)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- New York Medical College
Chronic Low-back Pain (cLBP)
Melatonin for Patients With Chronic Low Back Pain
Low back pain is one of the conditions causing more disability worldwide. The use of pain medications is substantial in patients with chronic LBP. But the efficacy of commonly used analgesics is modest.
- Trial name
- MELBACK (NCT06859957)
- Testing
- Melatonin 10 mg
- Where
- Netherlands
- Volunteers
- 222 people
- Sponsor
- Bart Koes
Chronic Nonspecific Low Back Pain
Effects of SIS Therapy in Individuals With Chronic Nonspecific Low Back Pain
Brief Summary - buraya yapıştırın Chronic nonspecific low back pain is a common condition that can cause pain, limitations in daily activities, and reduced quality of life.
- Trial name
- NCT07839169
- Testing
- SIS Therapy, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Chronic Low Back Pain, Foot Reflexology
Foot Reflexology for Chronic Low Back Pain
The aim of this 2-year randomized, double-blinded clinical trial is to investigate the effect of 6 or 12 sessions of weekly 45-minute to 1-hour foot reflexology interventions on physical function and symptoms, pain…
- Trial name
- NCT06828016
- Testing
- foot reflexology, usual foot care
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Fu Jen Catholic University Hospital
Low Back Pain, Functional Reach
The Relationship Between Transversus Abdominis Muscle Architecture and Upper Extremity Function in Patients With Chronic Low Back Pain
Core stability is the ability to control the position and movement of the trunk for optimal production, transfer, and control of forces in the upper and lower extremities during functional activities.
- Conditions
- Low Back Pain, Functional Reach, Scapular Dyskinesis, Core Muscles
- Trial name
- NCT07474610
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ilayda Dilan Isik
Chronic Low-back Pain (cLBP)
Effects of Vertebral Axial Loading Walking Combined With Core Stabilization Exercises in Individuals With Chronic Low Back Pain
Chronic low back pain is a common musculoskeletal condition persisting for more than three months and is associated with pain, functional limitations, impaired balance, altered proprioception, reduced trunk muscle performance…
- Trial name
- NCT07334782
- Testing
- Exercise - Core Stabilization Exercise Program, Core Stabilization Exercises Plus Vertebral Axial Loading Walking Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Hacettepe University
Chronic Low Back Pain (CLBP), Low Back Pain
Chronic Low Back Pain and Osteopathic Manipulation Treatment
The goal of this clinical trial is to learn if adding Osteopathic Manipulative Therapy (OMT) to the usual medical care provided at the VA (usual VA care) improves treatment outcomes in individuals with chronic low back pain…
- Trial name
- NCT07161661
- Testing
- Usual VA Care, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Edward Hines Jr. VA Hospital
Chronic Low-back Pain, Vertebrogenic Pain Syndrome
Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain
Compile real-world outcomes of commercially approved Intracept™ Intraosseous Nerve Ablation Systems in the treatment of patients diagnosed with vertebrogenic pain.
- Trial name
- IMPROVE (NCT06827262)
- Testing
- Intracept™ Intraosseous Nerve Ablation
- Where
- 22 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Boston Scientific Corporation
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Low Back Pain, Opioid Use
Neural Mechanisms of Meditation for Opioid-Treated Chronic Low Back Pain
The purpose of this research study is to see how a mindfulness meditation-based intervention affects pain. Specifically, we are interested in understanding the pain-relieving brain mechanisms of mindfulness meditation-based…
- Trial name
- NCT05607381
- Testing
- Meditation, Usual care
- Where
- 2 sites in United States
- Volunteers
- 188 people
- Sponsor
- University of Utah
Degenerative Disc Disease
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
The primary purpose of this study is to evaluate the efficacy of rexlemestrocel-L+HA compared to control in reducing low back pain at 12 months post-treatment and safety of a single injection of rexlemestrocel-L+HA injected into…
- Trial name
- HyaluronicAcid (NCT06325566)
- Testing
- Rexlemestrocel-L + HA mixture, Saline
- Where
- 40 sites in United States
- Volunteers
- 300 people
- Sponsor
- Mesoblast, Ltd.
Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction
Connective Tissue Dry Needling for Low Back Pain Related to Local Posterior Superior Iliac Spine Pain
This single-blind randomized controlled trial will aim to determine the effectiveness of a connective tissue dry needling (CTDN) technique, in reducing pain and improving function in individuals with chronic mechanical low back…
- Conditions
- Chronic Low Back Pain (CLBP), Sacroiliac Joint Dysfunction, Mechanical Low Back Pain
- Trial name
- NCT07345871
- Testing
- Connective tissue dry needling, Exercise therapy
- Volunteers
- 42 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Chronic Low Back Pain (CLBP)
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure.
- Trial name
- ASTRAL (NCT07222462)
- Testing
- Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Washington