Clinical trials: Back Surgery
Spine Pain, Spine Surgery
Influence of Pre-operative Back Muscle Exercise on Post-operative Outcomes After Spine Surgery
The purpose of this research study is to gather more information about how improving back muscle function before surgery might influence what happens to the spine and function after surgery.
- Trial name
- NCT06808022
- Testing
- Preoperative Resistance Exercise
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Back Pain
Comparison of Intraspinal Nerve Root Stimulation With Dorsal Column Stimulation
This study will systematically evaluate the programming parameters of the Precision Spinal Cord Stimulation Device to optimally relieve pain while minimizing any uncomfortable side effects.
- Trial name
- NCT00370773
- Testing
- Precision Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Scientific Corporation
Chronic Low Back Pain
A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
To administer the MSDR® (Musculoskeletal Disorder Reporting) instrument to document the musculoskeletal profile of patients with chronic low back pain, a prospective, non-randomized, multicenter treatment trial
- Trial name
- NCT00732394
- Testing
- MSDR
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedAppraise, Inc.
Posterior Cervical Spinal Surgery, Myelopathy Cervical
Cervical Orthosis Versus no Orthosis Following Multi-level Posterior Cervical Fusion
Use of cervical orthosis after instrumented posterior cervical spinal surgery is still widely practiced even though modern fusion techniques likely do not require additional stabilization from an external orthosis.
- Conditions
- Posterior Cervical Spinal Surgery, Myelopathy Cervical, Radiculopathy, Cervical, Spinal Stenosis Cervical
- Trial name
- NCT04308122
- Testing
- Cervical Orthosis (CO), No Orthosis
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Dr. Christopher Bailey
Operative Time, Grip Strength
Safety Study of Surgical Technique to Treat Acute Dorsal Trans-Scaphoid Perilunate Dislocations
The purpose of this study is to determine a surgical technique is effective in the treatment of acute dorsal trans-scaphoid perilunate dislocations.
- Conditions
- Operative Time, Grip Strength, Pain, Functional Status
- Trial name
- ADTPD (NCT00738127)
- Testing
- Open reduction and internal fixation
- Where
- China
- Volunteers
- 801 people
- Sponsor
- The Second Hospital of Qinhuangdao
Exotropia, Evaluation of Surgical Techniques in Correcting Exotropia
Evaluation of The Techniques in Correcting Large-Angle Exotropia
The aim of this study is to evaluate the techniques of combined lateral rectus muscle recession with hang back and combined lateral rectus muscle recession with z-tenotomy in correcting large-angle exotropia.
- Trial name
- NCT06084442
- Testing
- Evaluation of The Techniques of Lateral Rectus Muscle Combined Recession with Hang Back and Combined Recession with Z-Tenotomy in Correcting Large-Angle Exotropia
- Volunteers
- 50 people
- Sponsor
- Tanta University
Failed Back Surgery Syndrome
Study Comparing Conventional, Burst and High Frequency (HF) Spinal Cord Stimulation (SCS) in Refractory Failed Back Surgery Syndrome (FBSS) Patients After a 32-contact Surgical Lead Implantation
Chronic Back and/or Leg Pain (CBLP) after spinal surgical procedures, a condition commonly labelled Failed Back Surgery Syndrome (FBSS), affects between 15% and 40% of patients after a spine surgery.
- Trial name
- MULTIWAVE (NCT03014583)
- Testing
- Precision Spectra™ system
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Poitiers University Hospital
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Diabetic Macular Edema
A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME)
A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with DME.
- Trial name
- MIVI-II (NCT00412451)
- Testing
- ocriplasmin
- Where
- 15 sites in Belgium, Germany and 4 more
- Volunteers
- 51 people
- Sponsor
- ThromboGenics
Acute Postoperative Pain, Chest Wall Surgery
Prospective Feasibility, Analgesic Effectiveness, and Safety Study of a Visual Analog Scale-Guided Multimodal Pain Algorithm After Posterior Rib Remodeling With Osteosynthesis
This prospective single-group study will evaluate a visual analog scale-guided multimodal analgesia algorithm during the first five days after posterior rib remodeling with osteosynthesis.
- Trial name
- NCT07805928
- Testing
- VAS-Guided Multimodal Analgesia Algorithm, Ultrasound-Guided Thoracic Wall Regional Block
- Where
- Colombia
- Volunteers
- 160 people
- Sponsor
- Research Inc
Tympanostomy Tube Insertion
Prediciton of the Round Window Visibility Through Posterior Tympanotomy by CT Scan Analysis
It is difficult to predict the intraoperative visibility of the round window through the posterior Tympanostomy. In case of non-visualization, the surgeon may have to change operative technique during cochlear implant surgery.
- Trial name
- NCT03589209
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Lumbar Spinal Stenosis
Effect of the Posterior Ligamentous Complex on the Adjacent Segments Degeneration After Lumbar Surgery
To investigate whether destroying the adjacent posterior ligamentous complex (PLC) has an effect on adjacent segment degeneration (ASD) after L5/S1 posterior lumbar interbody fusion (PLIF)
- Trial name
- NCT04946487
- Testing
- total laminectomy
- Volunteers
- 80 people
- Sponsor
- Peking University Third Hospital
Regional Anesthesia Block, Regional Anesthesia
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)
Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus…
- Conditions
- Regional Anesthesia Block, Regional Anesthesia, Total Hip Replacement Surgery, Total Hip Arthroplasty \(THA\)
- Trial name
- Retro-PvF (NCT06342102)
- Testing
- PENG + LFCN block, FIC block
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale Edoardo Bassini
Lower Back Injury
Reduction of Risk for Low Back Injury in Theater of Operations
The investigators will conduct a controlled clinical trial with U.S. Army soldiers training to become combat medics. The purpose of this study is to determine if a 11-week, high intensity exercise program targeting the low back…
- Trial name
- NCT01401842
- Testing
- Lumbar ext. high intensity progressive resistance exercise, Low intensity core stabilization exercise
- Where
- 2 sites in United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hypospadias, Postoperative Pain
Caudal Epidural Block and DPNB in Hypospadias
Hypospadias, seen in every 200-300 births, is one of the most common congenital anomalies of the penis and is defined as the urethral meatus being located in the ventral part of the penis instead of its normal place.
- Trial name
- NCT04215874
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pain, Intractable, Pain, Chronic
Comparison of DTM™ SCS Therapy Combined With Conventional Medical Management (CMM) to CMM Alone in the Treatment of Intractable Back Pain Subjects Without Previous History of Lumbar Spine Surgery
The purpose of this investigational study is to document the safety, clinical effectiveness and health economic analytics of DTM™ SCS programming delivered through the Intellis™ neurostimulator in subjects with chronic…
- Trial name
- NCT06442410
- Testing
- DTM™ spinal cord stimulation therapy delivered via Intellis™ neurostimulator system, Conventional Medical Management (CMM)
- Where
- 12 sites in Belgium, Germany and 2 more
- Volunteers
- 115 people
- Sponsor
- MedtronicNeuro
Failed Back Surgery Syndrome, Lumbar Radiculopathy
EuroPainClinicsStudy IX ( EPCS IX )
This prospective investigator-initiated study compares the clinical effectiveness and safety of epiduroscopic adhesiolysis in patients with failed back surgery syndrome (FBSS) and in patients with lumbar radicular pain without…
- Conditions
- Failed Back Surgery Syndrome, Lumbar Radiculopathy, Chronic Low Back Pain, Epidural Fibrosis
- Trial name
- EPCS IX (NCT07411950)
- Testing
- Epiduroscopic mechanical adhesiolysis, Epidural pharmacologic therapy
- Where
- Slovakia
- Volunteers
- 141 people
- Sponsor
- EPC Education s.r.o.
Post-Traumatic Kyphosis
Surgical Management of Post-Traumatic Kyphosis
The goal of this observational study is to examine the safety and efficacy of posterior sugary only in addressing post traumatic kyphosis.
- Trial name
- NCT05644574
- Volunteers
- 20 people
- Sponsor
- Assiut University
Spine, Fluoroscopy for Spine Surgery
Evaluation the Impact of the "Pas" Technique Versus the "Standard" Technique on Radiation Exposure
The purpose of this study is to compare both techniques and analyze the data from the "Standard" technique to help design the "PAS" technique.
- Conditions
- Spine, Fluoroscopy for Spine Surgery, Back Pain, Sacroiliac Joint
- Trial name
- NCT06918197
- Testing
- PAS Technique, Standard Technique
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Orthospine Advance Health, Inc.
Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block
Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery
This study aims to evaluate the effectiveness of Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to Intercostal Nerve (ICN) block in terms of postoperative pain control, reduction of opioid analgesic…
- Conditions
- Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block, Post-operative Pain Management, VATS
- Trial name
- NCT07577908
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli City Hospital