Clinical trials: Bacteria
Dental Caries
Caries Management by Risk Assessment in Children
The goal of this study is to address the effectiveness of a modified cavity prevention protocol for 5-9 year-old children which emphasizes better diet modification, more frequent professional fluoride applications, and xylitol…
- Trial name
- NCT01310283
- Testing
- xylitol mints and fluoride varnish
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Diseases
Happy Gut Study - Fermented Vegetables and Cardiovascular Biomarkers
The purpose of this project is to determine whether regular consumption of fermented vegetables can decrease inflammation and change the types of bacteria that are normally present in the large intestine.
- Trial name
- NCT04887662
- Testing
- Fermented vegetable
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of North Florida
Multi Drug Resistant Bacteria
Risk Factors for Multidrug Resistant Bacteria at ICU Admission
The objective of this single-center prospective observational study is to evaluate possible independent risk factors for multidrug-resistant (MDR) bacteria upon ICU admission by analyzing comorbidities, epidemiological data, and…
- Trial name
- NCT05983861
- Testing
- Identification o Multi Drug Resistant Bacteria
- Volunteers
- 400 people
- Sponsor
- José Raimundo Araujo de Azevedo
Periodontitis
Diode Laser and SRP in Chronic Periodontitis
The purpose of this study is to compare the efficacy of photoablative and photodynamic diode laser in adjunct to scaling-root planing (PAPD+SRP) and SRP alone for the treatment of periodontitis.
- Trial name
- PAPD (NCT02407379)
- Testing
- PAPD+SRP
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Infectious Disease of Digestive Tract
The Use of Probiotics to Evaluate Colonization With Antimicrobial Resistant Bacteria
The purpose of this study is to evaluate the effectiveness of bacteria called Lactobacillus GG, a Probiotic, in preventing the growth of resistant bacteria in the digestive tract in patients on a ventilator.
- Trial name
- NCT01551186
- Testing
- Lactobacillus rhamnosus GG
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Washington University School of Medicine
Healthy Volunteers, Young Adult
The Impact of Selected Probiotic Bacteria on Gut Microbiota, Stress Indicators and Nutritional Status of Young Adults
Research on probiotic supplementation in the prevention and treatment of depressive and anxiety disorders and stress coping skills has been conducted for many years.
- Conditions
- Healthy Volunteers, Young Adult, Women
- Trial name
- PROBASTRESS (NCT06860581)
- Testing
- Intervention (Sanprobi®Stress)
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Staphylococcal Infections
Safety and Behavior of S. Aureus Immune Globulin Intravenous(Human), [Altastaph] in Patients With S. Aureus Bacteremia and Continuing Fever
Altastaph has been developed to help the removal of S. aureus from the bloodstream. The main objective of this study will be to test the safety and behavior of Altastaph in patients with S.aureus bacteremia and continuing fever
- Trial name
- NCT00063089
- Testing
- S. aureus Immune Globulin Intravenous (Human) 5%
- Volunteers
- 40 people
- Sponsor
- Nabi Biopharmaceuticals
Immunosuppression, Periodontal Disease
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
Background: Gum disease is a condition in which the tissue around the tooth root becomes swollen and infected. This condition can cause tooth loss if it is not treated.
- Conditions
- Immunosuppression, Periodontal Disease, Healthy Subjects, Healthy Volunteer
- Trial name
- NCT01568697
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Airborne Microorganisms, Particulate Matter (PM)
Clean Air for Everyone (CLAIRE): an Intervention Study to Reduce the Amount of Fine Particulate Matter and Microorganisms in Classroom Air
In this study, the investigators tested whether portable air cleaners can improve the air quality in primary school classrooms. Poor air quality can affect children's respiratory health and learning.
- Trial name
- CLAIRE (NCT07479420)
- Testing
- HEPA filter air cleaners, Ionization or plasma air cleaners
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lidwien Smit
Functional Dyspepsia, Small Intestinal Bacterial Overgrowth
Small Intestinal Bacterial Overgrowth: A Prospective Registry
The purpose of this study is to investigate the prevalence of small intestinal bacterial overgrowth (SIBO) in patients who will be undergoing an enteroscopy as an outpatient procedure with symptoms of functional dyspepsia.
- Trial name
- SIBO (NCT01822470)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Alcoholic Hepatitis
BActeriophages To Treat Liver Disease Eliminating Harmful Bacteria (BATTLE)
Alcoholic hepatitis is a disease with a high mortality rate with few treatment options improving survival. Recently certain bacterial strains has been correlated to survival in patients with alcoholic hepatitis.
- Trial name
- BATTLE (NCT05618418)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Nosocomial Infection
In Vitro Activity of Ceftolozane-tazobactam Against Contemporary Nosocomial Gram "-" Pathogens Isolated in Russia
Infections caused by resistant gram-negative bacteria are becoming increasingly prevalent and now constitute a serious threat to public health worldwide because they are difficult to treat and are associated with high morbidity…
- Trial name
- NCT04679610
- Where
- Russia
- Volunteers
- 700 people
- Sponsor
- The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC)
Bacteremia Sepsis
Resistell Phenotech AST to Determine the Antibiotic Susceptibility of Gram-negative Bacteria Causing Bacteremia
The aim of this study is to assess the sensitivity, specificity, and accuracy of the Resistell Phenotech device in testing antibiotic susceptibility of Gram-negative bacteria (i.e., E. coli or K.
- Trial name
- PHENOTECH-1 (NCT05613322)
- Testing
- Resistell Phenotech
- Where
- 3 sites in Austria, Spain and 1 more
- Volunteers
- 246 people
- Sponsor
- Resistell AG
Bacterial Vaginosis
The Impact of Probiotic Bacteria on the Efficacy of Anti-retroviral Therapy and Recurrence of Bacterial Vaginosis
Purpose of the proposed research is to determine the impact of probiotic yogurt supplemented with Lactobacillus rhamnosus (Fiti) compared to regular yogurt on the well-being of women living with HIV.
- Trial name
- NCT01258556
- Testing
- Yogurt supplemented with L. rhamnosus fiti, Yogurt not supplemented with a probiotic strain.
- Where
- Tanzania
- Volunteers
- 150 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pneumonia, Ventilator-Associated
Tobramycin Nebulization to Prevent Multidrug-Resistant Ventilator-Associated Pneumonia
The TOP-MDRVAP trial will test whether inhaled tobramycin can safely prevent pneumonia caused by multidrug-resistant bacteria in adults who need a breathing machine. Tobramycin is an antibiotic.
- Trial name
- TOP-MDRVAP (NCT07856355)
- Testing
- Tobramycin inhalation solution
- Where
- China
- Volunteers
- 574 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bacterial Infection
Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community
Detailed activity: Family members and caregivers of carrier residents will be screened for ESBL and MRSA. Screening will be performed by obtaining nares and perirectal cultures.
- Trial name
- NCT00765778
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Lumbar Disc Herniations
Detection of Bacteria in Herniated Nucleus Material in Lumbar Disc Herniations by Culture and PCR
The aim is to investigate if herniated nucleus material in lumbar disc herniations is infected with bacteria, and if so, to determine their prevalence (control group), and to determine if patients with pre-existing Modic changes…
- Trial name
- NCT02385968
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Spine Centre of Southern Denmark
Periodontitis
Salivary Bacterial Profiles in Relation to Periodontal Treatment
The purpose of the present investigation is to record and compare bacterial compositions in subgingival plaque samples and saliva samples in subjects receiving periodontal treatment.
- Trial name
- NCT02913248
- Testing
- Conventional periodontal treatment
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Chronic Arsenic Poisoning
Effect of Vitamin E on Skin Aerobic Bacteria in Palmar Arsenical Keratosis
This study will be conducted to observe any change in aerobic bacterial pattern on the skin of arsenicosis patients before and after administration of vitamin E (200 IU) capsules.
- Trial name
- NCT02468518
- Testing
- Vitamin E capsule
- Where
- Bangladesh
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Inflammation Gastrointestinal Tract
Identifying the Microbial Metabolome: The Missing Link Between Diet and Human Health
There is a lot of evidence to suggest that the bacteria in our gut play a major role in maintaining our health, but very little is known about the way in which this is achieved.
- Trial name
- NCT07591961
- Testing
- Food
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen