Clinical trials: Bacterial Overgrowth Syndrome
Gastric Bypass, Blind Loop Syndrome
Small Intestinal Bacterial Overgrowth Obese
The objective of this research is to determine the incidence of microbial overgrowth of the small intestine before and after a gastric bypass.
- Conditions
- Gastric Bypass, Blind Loop Syndrome, Bacterial Overgrowth Syndrome, Chromatography, Gas
- Trial name
- SIBOB (NCT02819037)
- Testing
- gas chromatography, Stool analysis for detection of malabsorption
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- Lille Catholic University
Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth
Small intestinal bacterial overgrowth (SIBO) can cause symptoms like bloating, stomach pain, and changes in bowel movements, significantly affecting quality of life.
- Trial name
- HERBA-SIBO (NCT06721884)
- Testing
- Artemisia Annua Leaf
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Coronary Heart Disease, Medicine, Chinese Traditional
HuoXin Pills Intervention on Patients With Coronary Heart Disease After Drug-Coated Balloon Implantation
This trial is a multi-center, randomized, double-blind, placebo, parallel controlled study. Objectively evaluates the curative effect of Huoxin Pills (concentrated pills) intervention on improving the prognosis of patients with…
- Trial name
- HAPPY-DCB (NCT05489016)
- Testing
- Yuekang Huoxin Pills (concentrated pills), Yuekang Huoxin Pills (concentrated pills)simulant
- Where
- 3 sites in China
- Volunteers
- 440 people
- Sponsor
- China National Center for Cardiovascular Diseases
Qi Stagnation and Blood Stasis Syndrome
The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome.
This is a multicenter, double-blind, randomized and placebo-controlled trial. The study aims to evaluate the effectiveness and safety of Xue-Fu-Zhu-Yu Capsule (XFZYC) for Qi Stagnation and Blood Stasis syndrome (QS\&BSS).
- Trial name
- TROTEASOTXZC (NCT03091634)
- Testing
- xue-fu-zhu-yu capsule, xue-fu-zhu-yu capsule simulated agent
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Effect of a Probiotic Formula on Reducing SIBO in IBS Patients
This randomized study evaluates the effectiveness of the a probiotic formula, compared with the antibiotic rifaximin, in the treatment of Small Intestinal Bacterial Overgrowth (SIBO) in Irritable Bowel Syndrome (IBS) patients.
- Trial name
- NCT04316806
- Testing
- Probiotic, Rifaximin
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- AB Biotics, SA
Age-related Macular Degeneration
A Phase Ⅱ Clinical Study of Sanhuangjingshimingwan in Wet( Neovascular)Age-related Macular Degeneration(wAMD) Subjects
The study is to evaluate the efficacy and safety of Sanhuangjingshimingwan in Wet AMD.
- Trial name
- NCT04486963
- Testing
- Sanhuangjingshimingwan
- Where
- 6 sites in China
- Volunteers
- 78 people
- Sponsor
- Tasly Pharmaceutical Group Co., Ltd
Staphylococcus Haemolyticus, Staphylococcal Infections
Staphylococcus Haemolyticus in the Neonatal Intensive Care Unit of CHSD in 2023: Analysis and Trends
This study looks at cases of Staphylococcus haemolyticus infections in newborns hospitalized in the Neonatal Intensive Care Unit (NICU) at the Saint-Denis Hospital in 2023.
- Conditions
- Staphylococcus Haemolyticus, Staphylococcal Infections, Sepsis, Catheter-Related Infections
- Trial name
- NCT07013864
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Coronary Heart Disease (CHD)
Clinical Evidence Based and TCM Phenotype Group Study of Zhilong Huoxue Tongyu Capsule in the Treatment of Stable Angina Pectoris of Coronary Heart Disease (Qi Deficiency and Blood Stasis Syndrome)
This study intends to prove the clinical effect of Zhidong Huoxue Tongyu capsule in the treatment of stable angina pectoris with qi deficiency and blood stasis syndrome from the perspective of TCM syndrome differentiation and…
- Trial name
- NCT06709638
- Testing
- Zhilong Huoxue Tongyu capsule
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Jiang Hanmei
PIK3CA-Related Overgrowth Spectrum (PROS)/Proteus Syndrome (PS)
A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)
This is a study of the safety and tolerability of oral miransertib (MK-7075) administered to participants at least 2 years of age with phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA)-related…
- Trial name
- NCT04980872
- Testing
- Miransertib
- Where
- 11 sites in United States, Australia and 3 more
- Volunteers
- 60 people
- Sponsor
- Merck Sharp & Dohme LLC
Ischemic Stroke
Clinical Application and Basic Study of Medicinal Fractions-based Herbal Combinations
The purpose of this study is to investigate the efficacy of fractions-based herbal combinations of clearing heat and promoting blood circulation treating acute ischemic stroke and the potential mechanism of it.
- Trial name
- NCT01636154
- Testing
- Ixeris of sonchifolia Hance, Panax notoginseng saponins, Ixeris of sonchifolia Hance combined with Panax notoginseng saponins
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Yunling Zhang
Coronary Heart Disease, Acute Myocardial Infarction
The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients
The purpose of this study is to test the expression of microRNAs related to the syndromes after the intervention of Tongguan capsule,preliminarily to investigate the mechanism of the effects of Tongguan capsule, and provide the…
- Trial name
- NCT02850627
- Testing
- Tongguan capsule
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Stroke, Ischemic, Coronary Artery Disease
BuqitongluO Granule for Qi Deficiency and Blood Stasis Syndrome
The main purpose of this trial is to evaluate the efficacy and safety of Buqitongluo Granule in treating qi deficiency and blood stasis syndrome, and explore the effect of the improvement of qi deficiency and blood stasis…
- Conditions
- Stroke, Ischemic, Coronary Artery Disease, Angina Pectoris, Stable, Diabetic Peripheral Neuropathy
- Trial name
- BOSS (NCT04408261)
- Testing
- Buqitongluo Granule, Standard care
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Dongzhimen Hospital, Beijing
Bacteremia Sepsis, Fungemia
Clinical and Medico-economic Evaluation of a Rapid Test (ePlex-BCID®, GenMark) for the Diagnosis of Bacteremia and Fungemia.
This study evaluates the clinical benefit of a rapid test for fast diagnosis of bacteremia and fungemia from positive blood cultures in case of sepsis.
- Trial name
- HEMOFAST (NCT03876990)
- Testing
- Multiplex PCR, Current strategy alone
- Where
- France
- Volunteers
- 312 people
- Sponsor
- University Hospital, Grenoble
Diarrhea Predominant Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial Overgrowth
The primary objective of this study is to determine whether giving SBI as a medical food starting with maintenance of health in the management of chronic loose and frequent stools in IBS-D subjects with SIBO after successful…
- Trial name
- NCT02251483
- Testing
- Serum-derived bovine immunoglobulin protein isolate (SBI)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Cedars-Sinai Medical Center
Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Small Bowel Bacterial Overgrowth Syndrome (SBBOS)
Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing
The objective of this study is to compare the efficacy of prokinetics versus antibiotics versus a combination of antibiotics plus prokinetics in the eradication of Small-Intestinal Bacterial Over-Growth Syndrome (SIBO) in those…
- Trial name
- SIBO (NCT01324895)
- Where
- United States
- Volunteers
- 944 people
- Sponsor
- University of Florida
Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth
The Efficacy of Probiotics as an Adjunct to Treatment of SIBO With Rifaximin
The goal of this clinical trial is to test the effectiveness of probiotic bacterial supplements as an additional therapeutic modality in patients with small intestine bacterial overgrowth who receive oral antibiotic treatment…
- Conditions
- Irritable Bowel Syndrome, Small Intestinal Bacterial Overgrowth, SIBO
- Trial name
- NCT06223685
- Testing
- Rifaximin (Xifaxan) 1200mg/day, Probiotic, XIFAXAN® (Rifaximin) 1600mg/day
- Where
- Poland
- Volunteers
- 129 people
- Sponsor
- Pomeranian Medical University Szczecin
Shoulder Tendinopathy, Shoulder Tendinitis
Electroacupuncture and Cupping for Shoulder Tendinitis
This study aims to evaluate the effectiveness of electroacupuncture combined with vacuum cupping therapy in treating simple periarthritis of the shoulder associated with the traditional medicine syndrome of Qi stagnation and…
- Trial name
- NCT07545785
- Testing
- Electroacupuncture, Vacuum Cupping Therapy
- Where
- 2 sites in Vietnam
- Volunteers
- 54 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Irritable Bowel Syndrome, Abdominal Pain
Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster
A 3-month study was conducted in flood victims from affected villages in the Tumpat district, Kelantan. Participants were given either probiotic, Bifidobacterium infantis M63 (M-63 group) or no probiotics (control group) for…
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Small Intestinal Bacterial Overgrowth
- Trial name
- NCT03318614
- Testing
- Probiotics M-63, Control group
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Irritable Bowel Syndrome
Efficacy of Rifaximin to Treat Diarrhea-predominant Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common disease and the pathogenesis of this disease includes central and peripheral mechanisms.
- Trial name
- NCT02565654
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Bacterial Overgrowth Syndrome Small Bowel, Heart Failure with Preserved Ejection Fraction
Rifaximin and Cardiac Function in Patients with Heart Failure with Preserved Ejection Fraction
Single-center, double-blind, randomized, controlled intervention study of the effect of correction of bacterial overgrowth syndrome in the small intestine (SIBO) on cardiac function in patients with heart failure with preserved…
- Trial name
- SIBO-HFpEF (NCT06652087)
- Testing
- Rifaximin, Standard HFpEF treatment
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University