Clinical trials: Bacterial Vaginosis
Candidiasis, Vulvovaginal, Recurrent Candidiasis of Vagina
The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms
The aim of the study is to investigate the efficacy of Fluconazol versus L-Mesitran in the treatment of patients with recurrent vulvovaginal candidiasis. Vaginal swabs will be analyzed after 1, 6 and 12 months.
- Trial name
- NCT05367089
- Testing
- Fluconazole, L-Mesitran
- Where
- 2 sites in Netherlands
- Volunteers
- 252 people
- Sponsor
- Maastricht University Medical Center
Trichomonas Vaginitis, Bacterial Vaginitis
Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and Secnidazole
This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metronidazole (MTZ) and oral single-dose secnidazole (SEC) for the…
- Trial name
- NCT06261840
- Testing
- Metronidazole 500 mg, Secnidazole 2000 MG
- Where
- 4 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Tulane University
Bacterial Vaginoses
Therapeutic Lactose to Support Vaginal Microbiota
The aim of the study was to investigate whether the administration of a vaginal tablet containing lactose can modulate the bacterial flora of women with bacterial vaginosis (BV).
- Trial name
- NCT03878511
- Testing
- Lactose
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Bacterial Vaginosis, Fungal Vaginal Infections
Clinical Protocol CERN Feasibility Study
The goal of this clinical trial is to learn if the intravaginal Cern device works to treat bacterial vaginosis and fungal vaginitis in premenopausal women. It will also learn about the safety of the device.
- Trial name
- NCT06933420
- Testing
- Cern Device
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Cern Corporation
Patients With Bacterial Vaginosis
Effects of Lacticaseibacillus Rhamnosus LRa05 on Bacterial Vaginosis and Ovarian Function in Women
In this study, Lacticaseibacillus rhamnosus LRa05 was selected as test preparations to observe the clinical efficacy in the intervention trial of combined antibiotic therapy, and to evaluate its effects on the cure rate…
- Trial name
- NCT06821789
- Testing
- Probiotic
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Bacterial Vaginosis, Vulvovaginal Candidiasis
Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal Infection
The purpose of this clinical trial is to investigate the clinical efficacy and safety of a Live Biotherapeutic Product (BGY-1601-VT) intended as a first line of treatment in cases of acute vaginal infection without upfront…
- Trial name
- ELINA (NCT06450990)
- Testing
- BGY-1601-VT
- Volunteers
- 165 people
- Sponsor
- NEXBIOME THERAPEUTICS
Bacterial Vaginosis, HIV
The Effect of Norethisterone Enanthate on Recurrent Bacterial Vaginosis
The proposed study, Hormonal Contraception \& BV (HCBV), will investigate the effect of NET-EN and DMPA on recurrent BV, vaginal microbiota and inflammatory markers among women at high risk for HIV in Kampala, Uganda.
- Trial name
- HCBV (NCT02905890)
- Testing
- Norethisterone enantate, Condoms
- Where
- Uganda
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Bacterial Vaginosis
A Pilot Study to Evaluate the Efficacy and Safety of Lactobacillus Species Suppositories on Vaginal Health and pH
Most of the methods involved in the treatment of BV include antibiotics. Some of the antibiotics used for this include metronidazole, clindamycin and fluconazole. The antibiotics inhibit the growth of anaerobes that support G.
- Trial name
- NCT05060029
- Testing
- Lactobacillus Species
- Where
- 5 sites in India
- Volunteers
- 75 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Vaginitis, Bacterial Vaginosis
Point of Care Diagnosis of Vaginal Infections
Vaginal infections are a common gynecologic issue and may cause significant symptoms and discomfort for individuals. Point of care tests are used to diagnose infections in the office, with an advantage of quick diagnosis and…
- Conditions
- Vaginitis, Bacterial Vaginosis, Yeast Vaginitis, Trichomonas Vaginitis
- Trial name
- PAT (NCT06438575)
- Testing
- Xpert® Xpress MVP test, Usual Care
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- Sharon L Hillier
Chlamydia, Gonorrhea
Screening With Tampons: Evaluating Diagnostic Accuracy and HPV and Assessing Participant Views
Diagnostic trial comparing the diagnostic accuracy of the DAYE Diagnostic Tampon (DDT) with a vaginal swab (self-collected and clinician taken).
- Conditions
- Chlamydia, Gonorrhea, Bacterial Vaginosis, Human Papilloma Virus
- Trial name
- STAMP (NCT06154239)
- Testing
- DAYE Diagnostic Tampon, Vaginal self-swab, Clinician vaginal swab
- Where
- United Kingdom
- Volunteers
- 617 people, healthy volunteers welcome
- Sponsor
- Anne's Day Ltd
Bacterial Vaginosis
Precision Vaginal Microbiome Transplantation in Women With Bacterial Vaginosis
The aim of this study was to explore the efficacy and safety of a new vaginal microbiome transplantation technique, using Lactobacillus cispatus from healthy donors as a treatment of bacterial vaginosis.
- Trial name
- NCT06263465
- Testing
- Lactobacillus cispatus
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhujiang Hospital
Sexual Transmitted Disease, Vaginosis, Bacterial
Impact of Internal Menstrual Protections on Immunity and Vaginal Microbiota
The availability, effectiveness, and safety of menstrual protection represent a key public health issue. However, research on women's menstrual and sexual health remains extremely limited.
- Conditions
- Sexual Transmitted Disease, Vaginosis, Bacterial, Mycosis, Urogenital Disease
- Trial name
- CUPS2 (NCT07199998)
- Testing
- Samples collection (whole blood, urine, vaginal and cervical cells)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Vulvovaginal Candidiasis
Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis
This study evaluates the effect of a multi-strain probiotic on the risk of recurrence and severity of symptoms in females with recurrent vulvovaginal candidiasis (R-VVC).
- Trial name
- PROVELIA (NCT06480604)
- Testing
- Probiotic
- Where
- 6 sites in India
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Bacterial Vaginosis
Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis
N-Acetyl cysteine (NAC) is an amino acid with strong antioxidant, mucolytic and antibacterial properties, and is produced within the human body.Its effect in biofilms has been tested in several bacteria.
- Trial name
- NCT01841411
- Testing
- N-Acetyl cysteine, Metronidazole + N-Acetyl cysteine, metronidazole
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Minia University
Vaginal Dysbiosis, Vaginal Disease
Feasibility of an Oral Intervention for Sexual Health in Transgender Men
Transgender men (TGM) have a high incidence of sexually transmitted infected (STIs), including HIV, HPV and bacterial N. gonorrhea and C. trachomatis.
- Conditions
- Vaginal Dysbiosis, Vaginal Disease, Molecular-bacterial Vaginosis
- Trial name
- TEST-F (NCT06470906)
- Testing
- Probiotic Group
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Columbia University
Bacterial Vaginosis
Bioequivalence of Metronidazole Gel, 0.75% in the Treatment of Bacterial Vaginosis
The purpose of this study was to demonstrate comparable efficacy, safety, and tolerability of Teva Pharmaceuticals USA's generic formulation of Metronidazole Vaginal Gel, 0.75% and 3M Pharmaceuticals' MetroGel-Vaginal®…
- Trial name
- NCT01020396
- Testing
- Metronidazole
- Where
- 37 sites in United States
- Volunteers
- 579 people
- Sponsor
- Teva Pharmaceuticals USA
Bacterial Vaginosis
Effect of Different Courses of Lactobacilli Treatment on Bacterial Vaginosis and Pregnancy Outcomes
The purpose of this study is to examine the effect of lactobacillus preparation on Bacterial vaginosis (BV) in low-risk pregnant women and to evaluate the value of double courses for the patients with durative positive result.
- Trial name
- BV (NCT01421615)
- Testing
- Vaginal capsules of lactobacilli
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Bacterial Vaginosis, Vulvovaginal Candidiases
Light Treatment of Vaginal Infections in Reproductive Age Women
Antimicrobials have helped in managing vaginal dysbiotic conditions such as bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC).
- Trial name
- NCT06985433
- Testing
- Vaginal light therapy - Once, Vaginal Light Therapy - Twice
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- UVISA Health ApS
Bacterial Vaginosis
Inflammation and Treatment of Bacterial Vaginosis Near Term
Most studies demonstrate that untreated bacterial vaginosis increases the rate of preterm birth. Despite this, there is no evidence that screening and treatment of asymptomatic bacterial vaginosis nor interpregnancy treatment of…
- Trial name
- NCT00720291
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Medical University of South Carolina
Pregnancy, Prematurity
Clindamycin to Reduce Preterm Birth in a Low Resource Setting
Preterm birth has been linked to certain types of vaginal infections. The goal of this study is to determine if giving women pregnant between 13-20 weeks with an elavated vaginal pH(evidence of this type of infection)Oral…
- Conditions
- Pregnancy, Prematurity, Preterm Birth, Bacterial Vaginosis
- Trial name
- NCT01800825
- Testing
- Clindamycin
- Where
- India
- Volunteers
- 1,726 people
- Sponsor
- Christiana Care Health Services