Clinical trials: Bacterial Vaginosis
Bacterial Vaginosis
Analysis of Ameliorative Effects of Oral Probiotics on Bacterial Vaginosis
The purpose of this study is to analyze the ameliorative effects of oral probiotics on bacterial vaginosis.
- Trial name
- NCT03116789
- Testing
- probiotics
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- GenMont Biotech Incorporation
Sexually Transmitted Infections, HIV Infections
Sexually Transmitted Infections Among African American Women Who Have Sex With Women
The purpose of this study is to determine the rates of sexually transmitted infections (STI) among a group of African American women who have sex with women (AA WSW).
- Trial name
- WSW (NCT01043081)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Mississippi Medical Center
Bacterial Vaginosis, Candida Vaginitis
Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis
In the clinical performance part of this study, prospectively acquired clinician-collected and clinician-instructed, self-collected vaginal swab specimens collected in cobas® PCR Media will be taken from a minimum of 500…
- Trial name
- NCT06975436
- Testing
- cobas® BV/CV test, BD Max™ Vaginal Panel, Cepheid Xpert Xpress MVP
- Where
- 10 sites in United States, Bulgaria and 1 more
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Recurrent Vulvovaginal Candidiasis
Safety and Immunogenicity Study of a Virosomal Vaccine Against Recurrent Vulvovaginal Candida Infection
Pevion Biotech develops a state-of-the-art vaccine against recurrent vulvovaginal candidiasis (RVVC) caused by the pathogenic form of Candida albicans especially in pre-menopausal women of childbearing age with a history of…
- Trial name
- NCT01067131
- Testing
- PEV7C1, PEV7C9, PEV7B2
- Where
- 2 sites in Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pevion Biotech Ltd
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide
The primary aims of the study were to assess the safety and acceptability of PC-515 when applied vaginally at least three times weekly for 12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213031
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Population Council
Vulvovaginal Candidiasis
Comparative Efficacy Study of 10 mg Dequalinium Chloride (Fluomizin) in the Treatment of Vulvovaginal Candidiasis
A clinical study to compare the clinical efficacy of vaginal tablets containing 10mg dequalinium chloride (Fluomizin) with the clinical efficacy of 100mg clotrimazole in patients suffering from vulvovaginal candidiasis, to assess…
- Trial name
- NCT02242695
- Testing
- Fluomizin vaginal tablets, Canesten vaginal tablets
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Medinova AG
Recurrent Bacterial Vaginosis (BV)
Dose-ranging Study of SPL7013 Gel for the Prevention of Bacterial Vaginosis (BV)
The purpose in this clinical study is to determine the efficacy of SPL7013 Gel for the prevention of recurrence of bacterial vaginosis.
- Trial name
- NCT01437722
- Testing
- 1% SPL7013 Gel, 3% SPL7013 Gel
- Volunteers
- 205 people
- Sponsor
- Starpharma Pty Ltd
Bacterial Vaginosis
Role of Oral Lactobacilli on Vaginal Flora of Pregnant Women
Bacterial vaginosis (BV) occurs in about 20% of pregnancies and responsible for up to 25% of visits to gynecological clinics. BV is characterized by a shift in vaginal bacterial flora from lactobacilli to pathogenic bacterial…
- Trial name
- NCT04638257
- Testing
- Lactobacilli rhamnosus GR-1 and Lactobacilli fermentum RC-14
- Volunteers
- 49 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Candidiasis, Vulvovaginal
A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasis
The overall aim of this study is to investigate if vaginally applied 1% chlorhexidine gluconate (CHG) could be an alternative treatment to oral fluconazole (FLZ), both during an acute episode and as prophylaxis, against recurrent…
- Trial name
- NCT05059145
- Testing
- Chlorhexidine Gluconate, Fluconazole
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Vulvovaginal Candidiasis
VVC Sampling Study for Analysis Validation
This is a biomarker multi-centre study to validate an extraction method of fungal and bacterial DNA extracted from vaginal swabs from adult women with confirmed VVC.
- Trial name
- NCT05327192
- Testing
- No intervention, only sampling
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- Gedea Biotech AB
Vaginal Infections, Bacterial Vaginosis
Va-Sense - Bacterial Vaginosis Once A Week Screening And Treatment To Reduce Infective Complications, Abortion And Preterm Delivery In Pregnant Women With Previous Preterm Delivery
The purpose of this study is to determine whether screening of pregnant women with history of previous preterm delivery, once a week, for bacterial vaginosis using VA-SENSE, and treatment of positive women will reduce the risk of…
- Conditions
- Vaginal Infections, Bacterial Vaginosis, Late Miscarriage, Preterm Birth
- Trial name
- NCT01152528
- Testing
- VA-SENSE
- Where
- Israel
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Common Sense
Bacterial Infections, Bacterial Infections and Mycoses
Large Algorithm Setting and Validation Study
In this pilot study, prospectively acquired clinician-collected and participant-collected vaginal swab specimens will be obtained from up to 1000 individuals with signs and symptoms of vaginitis to develop and validate a…
- Conditions
- Bacterial Infections, Bacterial Infections and Mycoses, Infections, Vaginitis
- Trial name
- LAVA (NCT07607470)
- Testing
- Nanopath Vaginitis Assay, BD Max™ Vaginal Panel, Cepheid Xpert® Xpress MVP
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Nanopath, Inc
Bacterial Vaginosis, Vaginal Dysbiosis
AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm Birth
Preterm birth is a major cause of mortality and long-term disability. Bacterial vaginosis (BV) is a frequent form of dysbiosis that is often asymptomatic and increases the risk of preterm birth.
- Conditions
- Bacterial Vaginosis, Vaginal Dysbiosis, Premature Delivery
- Trial name
- AUTOP 2 (NCT06349122)
- Testing
- Vaginal flora abnormalities screening and quantification using molecular biology technique, Azithromycin, Ceftriaxone
- Volunteers
- 1,794 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Vulvovaginal Candidiasis (VVC)
ProF-001_Phase IIa
This is a multi-center, randomized, prospective, active-controlled, double-blind, dose-escalation study comparing dose response of clinical efficacy, safety, local tolerability of three different doses of ProF-001/Candiplus®…
- Trial name
- NCT03115073
- Testing
- Candiplus, Clotrimazole
- Where
- 3 sites in Austria
- Volunteers
- 84 people
- Sponsor
- ProFem GmbH
Vaginal Diseases
Probiotic for Vaginal Candidiasis in Pregnant Women
This project aims to study the benefits of a probiotic product, STP4 for vaginal health properties, primarily prevention of vaginal candidiasis, among pregnant women in second and third trimester pregnancy.
- Trial name
- NCT03940612
- Testing
- STP4 (product with probiotics)
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Vulvovaginal Candidiases
Epidemiological Study in Subjects With Vulvovaginal Candidiases
Epidemiological study about the clinical and microbiological progress in subjects under treatment for a severe vulvovaginal candidiases episody
- Trial name
- NCT03064789
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Dr. Santiago Palacios
Vaginal Candidiasis, Bacterial Vaginosis
Observational Program Neo-Penotran® Forte
Vaginitis is the most common gynecologic diagnosis in the primary care setting. In approximately 90 percent of affected women, this condition occurs secondary to bacterial vaginosis, vulvovaginal candidiasis, trichomoniasis or…
- Conditions
- Vaginal Candidiasis, Bacterial Vaginosis, Trichomonal Vaginitis
- Trial name
- NCT01335373
- Testing
- Metronidazole/Miconazole (Neo-Penotran Forte, BAY86-5276)
- Where
- Kazakhstan
- Volunteers
- 13,024 people
- Sponsor
- Bayer
Bacterial Vaginosis
A Pilot Open-label Randomized Study of Lactofiltrum in Women With Bacterial Vaginosis
This is a phase II multicenter randomized open-label clinical study that will determine whether treatment with Lactofiltrum (orally administered tablets) in combination with antibiotic therapy (metronidazole) is effective in…
- Trial name
- LF-BV-09 (NCT01089348)
- Testing
- Lactofiltrum + Metronidazole, Metronidazole
- Where
- 2 sites in Russia
- Volunteers
- 90 people
- Sponsor
- Avva Rus, JSC
Recurrent Vulvovaginal Candidiasis
Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC)
This study is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of oral ibrexafungerp (formerly "SCY-078") compared to placebo in female subjects 12 years and older…
- Trial name
- CANDLE (NCT04029116)
- Testing
- Fluconazole Tablet, IBREXAFUNGERP
- Where
- 25 sites in United States
- Volunteers
- 440 people
- Sponsor
- Scynexis, Inc.
Candidiasis, Vulvovaginal
Study Evaluating the Optimal Dosage for Equivalence Between Lcr Regenerans® Capsules and Tablets (Lactobacillus Rhamnosus Lcr35®) on the Vaginal Flora Colonisation
The primary objective of this study is to study the vaginal flora colonisation equivalence between the tablet and capsule dosage forms of a treatment with Lcr Regenerans® between D0 (V1) and Dend of treatment.
- Trial name
- COMPRIGEL (NCT02730494)
- Testing
- Lcr Regenerans® vaginal capsules, Lcr Regenerans® vaginal tablet
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biose