Clinical trials: Bacterial Vaginosis
Vaginosis, Bacterial, Vaginal Flora Imbalance
Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment
Randomized, blinded vehicle-controlled multicenter clinical trial (MAT072017) to determine the effect of vaginal ovules containing 2 mg of the tea extract Matuzalem on the subjective symptoms (5-point scale pruritus (itching)…
- Trial name
- MAT072017 (NCT04171947)
- Testing
- Matuzalem ovule, Vehicle ovule
- Where
- 14 sites in Czechia
- Volunteers
- 274 people
- Sponsor
- Value Outcomes Ltd.
Candidiasis, Vaginosis, Bacterial
Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal Infections
The purpose of this study is to determine whether a formula of boric acid and probiotics for vaginal application is effective in the treatment of symptomatic episodes of vulvovaginitis in comparison to pharmacological reference…
- Trial name
- DOBO (NCT02860845)
- Testing
- Boric acid and probiotics, Antibiotic (Clindamycin), Antifungal (Clotrimazole)
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Laboratorios Ordesa
Bacterial Vaginosis
A Study of the New Medical Device Polybactum®
The POLARIS trial is designed as a multicenter, open label, non-comparative, 3 months, clinical study. Interventional, non-controlled, multicenter trial with a prospective design on one cohort of patients
- Trial name
- POLARIS (NCT02863536)
- Testing
- Polybactum®
- Where
- Romania
- Volunteers
- 56 people
- Sponsor
- Effik Italia S.p.A.
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert
Bacterial Vaginoses
Treatment of BV With Donaxyl and a Molecular Test of Cure
. Treatment with dequalinium chloride vaginal tablets for 6 days had a cure rate lower than expected; only 37% of patients were considered cured one month after treatment.
- Trial name
- NCT04057482
- Testing
- D
- Volunteers
- 58 people
- Sponsor
- Skaraborg Hospital
Bacterial Vaginosis
Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal Candida
From the earlier studies the investigators have treated women with bacterial vaginosis and cronic vulvovaginal candida. The investigators have then treated them with laktobacilli 10 days for 2 month.
- Trial name
- NCT02295579
- Testing
- lactobacillus (EcoVag)
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Skaraborg Hospital
Bacterial Vaginosis
Efficacy and Safety Study of SPL7013 Gel to Prevent the Recurrence of Bacterial Vaginosis (BV)
A double-blind, phase 3 study to determine the efficacy of SPL7013 Gel when administered on alternate days for 16 weeks, compared to placebo gel in preventing the recurrence of BV in women with a history of recurrent BV.
- Trial name
- NCT02237950
- Testing
- Metronidazole oral tablets 500mg, 1% SPL7013 Gel
- Where
- 45 sites in United States, Canada and 1 more
- Volunteers
- 586 people
- Sponsor
- Starpharma Pty Ltd
Bacterial Vaginosis
A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis
The primary objective of the study is to assess the efficacy of 1% SPL7013 Gel compared to placebo gel for the treatment of bacterial vaginosis (BV).
- Trial name
- NCT01577238
- Testing
- 1% SPL7013 Gel
- Volunteers
- 250 people
- Sponsor
- Starpharma Pty Ltd
Bacterial Vaginosis
A Phase 3 Study of SPL7013 Gel (VivaGel) for the Treatment of Bacterial Vaginosis
The primary objective of the study is to assess the efficacy of 1% SPL7013 Gel compared to placebo gel for the treatment of bacterial vaginosis (BV).
- Trial name
- NCT01577537
- Testing
- 1% SPL7013 Gel
- Volunteers
- 251 people
- Sponsor
- Starpharma Pty Ltd
Bacterial Vaginosis
Rwanda Vaginal Microbiota Restoration Study
A pilot randomized controlled clinical trial of intermittent use of two different vaginal lactobacilli-containing probiotics, and oral metronidazole, to prevent bacterial vaginosis recurrence.
- Trial name
- VMB (NCT02459665)
- Testing
- Vaginal multiple lactobacilli-containing probiotic for prevention of BV recurrence, Prophylactic use of metronidazole pills (500 mg), Vaginal Lcr35-containing probiotic for prevention of BV recurrence
- Volunteers
- 68 people
- Sponsor
- Janneke van de Wijgert
Bacterial Vaginosis
Dose Ranging Study of SPL7013 Gel for Treatment of Bacterial Vaginosis (BV)
The purpose of this study is to determine the efficacy of SPL7013 Gel in the treatment of bacterial vaginosis.
- Trial name
- NCT01201057
- Testing
- 0.5% SPL7013 Gel, 1.0% SPL7013 Gel, 3.0% SPL7013 Gel
- Where
- 5 sites in United States
- Volunteers
- 132 people
- Sponsor
- Starpharma Pty Ltd
Bacterial Vaginosis
Dietary Supplementation of Lactogyn in Women With Bacterial Vaginosis
The objective of the study is to determine clinical efficacy of Lactogyn (Lactobacillus Crispatus, L. brevis, L.acidophilus) in prevention of recurrent BV
- Trial name
- NCT03601429
- Testing
- Lactogyn
- Where
- Ukraine
- Volunteers
- 166 people
- Sponsor
- Vesale Pharmaceutica
Bacterial Vaginoses
Therapeutic Lactose to Support Vaginal Microbiota
The aim of the study was to investigate whether the administration of a vaginal tablet containing lactose can modulate the bacterial flora of women with bacterial vaginosis (BV).
- Trial name
- NCT03878511
- Testing
- Lactose
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
BACTERIAL VAGINOSIS
Bacterial Vaginosis Screening at IUD Insertion
A number of studies have shown a higher prevalence of BV among IUD users.13,,14 None, however, have screened women prior to inserting the IUD.
- Trial name
- NCT00802386
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Bacterial Vaginitis
Honghe Fujie Lotion for the Treatment of Bacterial Vaginosis
This is a Randomized, Positive -Controlled, Multi-center Trial enrolling 240 subjects with Bacterial Vaginosis who will be randomized at a ratio of 1:1 to receive active Honghe Fujie lotion or Metronidazole Suppositories.
- Trial name
- NCT03446443
- Testing
- Honghe Fujie lotion, Metronidazole Suppositories
- Where
- 8 sites in China
- Volunteers
- 240 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Vaginosis, Bacterial
Pathogenesis of Bacterial Vaginosis in Women Who Have Sex With Women
The objectives of this study are to: (1) use cultivation-independent molecular methods to determine the sequence of microbiological events culminating in bacterial vaginosis (BV) among sexually active African American women who…
- Trial name
- NCT02272231
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bacterial Vaginosis
Safety and Efficacy of 5% Monolaurin Vaginal Gel Administered Intravaginally for the Treatment of Bacterial Vaginosis
This is a Phase II, Double-Blind, Randomized, Placebo-Controlled, Multi-center Trial enrolling 120 subjects with Bacterial Vaginosis who will be randomized at a ratio of 2:1 to receive active test article (5% Monolaurin Vaginal…
- Trial name
- NCT02709005
- Testing
- 5% Monolaurin Vaginal Gel
- Where
- 3 sites in United States
- Volunteers
- 109 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bacterial Vaginosis, HIV
Effects of Contraceptive Ring on Vaginal Microbiota, HIV Shedding and Local Immunity
The investigators propose to explore the hypothesis-supported by limited data-that a contraceptive vaginal ring (CVR) that is commonly used in the United States, the NuvaRing, will enhance women's genital and reproductive health.
- Trial name
- NCT02445989
- Testing
- NuvaRing
- Where
- Kenya
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Washington
Bacterial Vaginosis Treatment
Vaginal Clindamycin Cream Plus Vaginal Probiotic for Bacterial Vaginosis
Vaginal Clindamycin Cream Plus Vaginal probiotic for treatment of Bacterial Vaginosis
- Trial name
- NCT03234517
- Testing
- Vaginal Clindamycin Cream, Vaginal Probiotic
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Preterm Birth
Study of the Risk of PREMaturité According to the Balance of Bacterial Flora VAginale
Objective To compare vaginal microbiota in the first trimester of pregnancy between spontaneous preterm and term deliveries
- Trial name
- PREMEVA2 (NCT03618836)
- Testing
- Microbiological and biological patterns on vaginal samples
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille