Clinical trials: Balanced
Healthy
A Single Dose Metabolism and Mass Balance Study of 14C-ABR-215050 in Healthy Subjects
This is a single site, open label, single dose, non-randomized study in healthy male and female subjects. The subjects will be evaluated for plasma, urine and feces levels of 14C-ABR-215050 during 21 days.
- Trial name
- NCT01048203
- Testing
- ABR-215050
- Where
- Sweden
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Active Biotech AB
Mass Balance Study in Healthy Subjects
Mass Balance Study of [14C]JAB-21822
Mass Balance Study of [14C]JAB-21822 in China Healthy Subjects
- Trial name
- NCT05920941
- Testing
- [14C]JAB-21822
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Allist Pharmaceuticals, Inc.
Normal Healthy Subjects
An Bioequivalence Study to Compare Two 2 mg/ml Liposomal Amphotericin B Injections in Healthy Subjects
The 2 × 2 crossover designed study is to evaluate the bioequivalence of two different liposomal amphotericin B injections after single IV infusion at the same dose in normal healthy subjects.
- Trial name
- NCT01652859
- Testing
- Liposomal Amphotericin B, AmBisome
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Taiwan Liposome Company
Healthy Volunteer
A Study to Assess the Mass Balance of [14C] ABBV-903 in Healthy Male Participants Following Single Oral Dose Administration
The purpose of this study is to evaluate the mass balance and safety of [14C] ABBV-903 in healthy male volunteers following a single oral dose administration.
- Trial name
- NCT05995366
- Testing
- ABBV-903
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- AbbVie
Sleep, Physical Performance
Nutritional Intervention to Enhance Sleep Quality and Quantity in Athletes
The primary objective is to assess the impact of two nutritional interventions vs. placebo on objective and subjective sleep measures in athletes.
- Conditions
- Sleep, Physical Performance, Cognitive Performance, Balance
- Trial name
- NCT05032729
- Testing
- Trypophan, Theanine and 5'AMP
- Where
- Australia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Healthy Volunteers
A Study Investigating [14C]-Labeled RO7269162 in Healthy Male Participants
This study will investigate how RO7269162 labeled with a carbon tracer ([14C]) is absorbed, metabolized, and eliminated by the body after a single dose in healthy male volunteers.
- Trial name
- NCT06733298
- Testing
- [ 14C]-labeled RO7269162
- Where
- Netherlands
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy Volunteers
Copanlisib Mass Balance Study
The study aims to provide understanding of the relative relevance of the different excretion pathways of Copanlisib in humans, as well as to characterize its metabolite profile.
- Trial name
- NCT02119221
- Testing
- Copanlisib (BAY80-6946)
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bayer
Solid Tumor
A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects
A Phase I, Open-label Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 Following a Single Oral Dose to China Healthy Male Subjects
- Trial name
- NCT05109832
- Testing
- 14C-IMP4297
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Impact Therapeutics, Inc.
Healthy Participants
Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB123667 in Healthy Male Participants
This study will assess the mass balance, pharmacokinetics, and metabolite profiles of a single oral dose of [14C] INCB123667 in healthy male participants.
- Trial name
- NCT07218744
- Testing
- INCB123667
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Immunogenicity, Healthy Volunteers
Comparative Immunogenicity Study of Multiple Doses of Proposed Pegfilgrastim Biosimilar, INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.
The study was an assessor-blind, balanced, parallel, randomized, two-treatment, comparative immunogenicity study of multiple doses of subcutaneous (SC) Pegfilgrastim injection (6 mg/0.6 mL; Intas Pharmaceuticals Ltd.
- Trial name
- NCT04015232
- Testing
- INTP5, US Neulasta
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Intas Pharmaceuticals, Ltd.
Healthy, Adult
Study Evaluating Effects of SAM-531 on Sleep Electroencephalogram (EEG) and Quantitative Wake EEG in Healthy Subjects
Primary: To evaluate the pharmacologic effect of single doses of SAM-531 on sleep EEG in healthy subjects.
- Trial name
- NCT00519298
- Testing
- SAM-531, Donepezil
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Post-operative Nausea and Vomiting
Mass-balance Study of [14C]-APD421 in Healthy Volunteers
Open-label, non-randomised, single dose study in 6 healthy male subjects to assess the mass balance recovery, metabolite profile, metabolite identification and pharmacokinetics of 14C-labelled APD421
- Trial name
- NCT02881840
- Testing
- 14C-APD421
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Acacia Pharma Ltd
Healthy
Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Galeterone
This is an open label, single dose, 1 period study of [14C] galeterone.
- Trial name
- NCT02729376
- Testing
- galeterone
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- LTN PHARMACEUTICALS, INC.
PMS, Menstrual Discomfort
Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome
This is an open-label observational single-group clinical trial to study the efficacy of a commercially available dietary supplement and its effect on common PMS and menstrual symptoms, as well as health-related biomarkers.
- Conditions
- PMS, Menstrual Discomfort, Menstrual Pain
- Trial name
- NCT05237661
- Testing
- Moon Balance
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Your Super, INC.
Healthy Volunteer
Study of [14C] ABBV-CLS-7262 in Healthy Male Volunteers Following Single Oral Dose Administration
The purpose of this study is to evaluate mass balance, pharmacokinetics and safety of [14C] ABBV-CLS-7262 in healthy, male volunteers following administration of a single oral dose.
- Trial name
- NCT06425003
- Testing
- [14C] ABBV-CLS-7262
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Calico Life Sciences LLC
Healthy Volunteers
Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male Volunteers
This study will assess the absorption, metabolism, excretion, mass balance, safety, and tolerability of a single oral administration of [14C]-CTP-543 in healthy male subjects.
- Trial name
- NCT04092712
- Testing
- [14C]-CTP-543
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Concert Pharmaceuticals
Gastroesophageal Reflux Disease
Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects
This study is a single-site, single-dose, non-randomized, open-label study to assess the absorption, metabolism, and excretion profile of [14C]X842 in healthy adult male subjects.
- Trial name
- NCT07107672
- Testing
- [14C]X842
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd
Healthy Volunteers
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule Under Fed Condition
The objective of the study is to compare the bioavailability and characterise the pharmacokinetic profile of Mycophenolate mofetil 250 mg capsules Panacea Biotech Ltd, India and Cellcept® 250 mg capsules Mycophenolate mofetil…
- Trial name
- NCT01080417
- Testing
- Mycophenolate Mofetil Capsule 250 mg
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Panacea Biotec Ltd
Healthy Participants
A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.
The purpose of this study is to learn how a certain amount of [14C] PF-06821497 is taken up into the bloodstream and removed from the body. The study is seeking participants who are: Males aged 18 years or older.
- Trial name
- NCT06392230
- Testing
- Oral [14C] PF-06821497, Oral PF-06821497, IV [14C] PF-06821497
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Molecular Mechanisms of Pharmacological Action
A Study to Investigate the Mass Balance of BTD-001
This is a single-centre, open-label, non-randomised, single oral dose study in healthy male subjects to assess the mass balance recovery of carbon-14 (14C)-BTD-001.
- Trial name
- HV103 (NCT03107013)
- Testing
- [14C]-BTD-001
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Balance Therapeutics