Clinical trials: Balanced
Blast Overpressure Exposure, Blast Injuries
Biomarkers of Brain Health in Blast Overpressure Exposure
The purpose of this study is to learn whether headsets that measure brainwaves can find early signs of changes in brain health in tactical operators who train near explosive blasts.
- Conditions
- Blast Overpressure Exposure, Blast Injuries, Brain Health, Occupational Exposure
- Trial name
- NCT07783048
- Testing
- Blast overpressure exposure during explosive breaching training
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Neurable, Inc
Healthy
Evaluation of Mass Balance and Absolute Bioavailability of GLPG3970
A study in healthy male volunteers to assess how the radiolabelled test medicine is taken up and broken down by the body when given by short infusion into a vein and when given by the mouth in the form of a tablet and an oral…
- Trial name
- NCT04907149
- Testing
- GLPG3970 film-coated tablet, [14C]GLPG3970 solution for infusion, [14]GLPG3970 oral solution
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Lakefront Biotherapeutics NV
Healthy Volunteers
Mass Balance Study of NV-5138 in Healthy Male Subjects.
The objective of this study is to assess the mass balance and routes of excretion of total radioactivity after a single oral dose of 1600 mg [14C]-NV-5138.
- Trial name
- NCT05152680
- Testing
- [14C]-NV-5138
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Navitor Pharmaceuticals, Inc.
Diabetes, Healthy
Comparison of Two Insulin Aspart Formulations in Healthy Volunteers
This trial is conducted in Africa. The aim of this trial is to determine if a new formulation (U200) of insulin aspart containing 200 U/mL is bioequivalent to that of a marketed insulin aspart formulation (U100).
- Trial name
- NCT01698697
- Testing
- insulin aspart
- Where
- South Africa
- Volunteers
- 24 people
- Sponsor
- Novo Nordisk A/S
Healthy Volunteers
A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants
The purpose of the study is to determine absorption, metabolism, and excretion of a single oral dose of [14C]-xevinapant. This information will enable assessment of absorption and clearance mechanisms of [14C]-xevinapant as well…
- Trial name
- NCT04962724
- Testing
- Radiolabelled Xevinapant 200 mg (Oral Solution), Radiolabelled Xevinapant 100 μg (IV Solution), Xevinapant 200 mg (Oral Solution)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Debiopharm International SA
Healthy
Mass Balance Recovery, Absorption, Metabolism and Excretion of [14C]-BLU-5937
This is a single-centre, open-label, non-randomised, single-period, single-dose study in healthy male subjects designed to assess the mass balance recovery, PK, metabolite profile and metabolite identification of [14C]-BLU-5937.
- Trial name
- NCT05244759
- Testing
- [14C]-BLU-5937
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bellus Health Inc. - a GSK company
Healthy
Bioequivalence Study of Fexofenadine Hydrochloride Orally Disintegrated Tablets 30 mg Under Fasting Condition
To assess the bioequivalence of Fexofenadine Hydrochloride Orally Disintegrating Tablets 30 mg of Dr. Reddy's Laboratories Limited, India comparing with that of Allegra® (containing fexofenadine hydrochloride) Orally…
- Trial name
- NCT01888718
- Testing
- Fexofenadine Hydrochloride
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Type 2 Diabetes Mellitus (T2DM)
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes
The goal of this clinical trial is to evaluate the efficacy and safety of Bofanglutide (GZR18) compared with Semaglutide in Latin American adults with type 2 diabetes mellitus who have inadequate glycemic control while receiving…
- Trial name
- NCT07628985
- Testing
- Bofanglutide, Semaglutide
- Where
- 7 sites in Mexico
- Volunteers
- 374 people
- Sponsor
- Carnot Laboratories
Healthy
Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fasting Conditions
The study was conducted as an open-label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Felodipine extended release tablets USP 10 mg (containing felodipine…
- Trial name
- NCT02327247
- Testing
- Felodipine, PLENDIL®
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Healthy
A Study Designed to See How [14C]-CORT125134 is Taken up, Broken Down and Removed From the Body
The study was designed to evaluate how CORT125134 is taken up, broken down and removed from the body when given as an oral capsule to healthy subjects.
- Trial name
- NCT03067376
- Testing
- [14C]-CORT125134
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Healthy
Study Evaluating the Bioavailability of Miricorilant With Optional Food Effect Assessment in Healthy Adult Subjects
This single-center, randomized, open-label study will assess the relative bioavailability of 2 miricorilant (CORT118335) tablet formulations.
- Trial name
- NCT07240116
- Testing
- Miricorilant Treatment A, Miricorilant Treatment B, Miricorilant Treatment C
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Corcept Therapeutics
Acute Leukemia
Study of Radiolabeled Revumenib in Adults With Acute Leukemia
This is an open-label study to evaluate the absorption, metabolism, and excretion (AME) of carbon-14 ([14C])-revumenib in participants with acute leukemia.
- Trial name
- NCT05406817
- Testing
- Revumenib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Syndax Pharmaceuticals
Ovarian Epithelial Cancer Recurrent
Bioequivalence Study of Doxorubicin Hydrochloride Liposome Injection
Bioequivalence study is proposed to be carried out on patients of ovarian cancer, who are already receiving or who in the opinion of their treating physicians are candidates for Doxorubicin liposomal injection therapy .
- Trial name
- NCT02260544
- Testing
- Doxorubicin Hydrochloride Liposome Injection
- Where
- 11 sites in India
- Volunteers
- 49 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Breast Cancer
Mass Balance Study of TQB3616
This is a clinical study exploring the mass balance of [14C] TQB3616 in healthy Chinese subjects aims to quantitatively analyze the total radioactivity in the feces of male healthy subjects after oral administration of [14C]…
- Trial name
- NCT06149611
- Testing
- [14C] TQB3616
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Dry Eye, Meibomian Gland Dysfunction
Evaluation of Neovis® Total Multi Versus Systane® Balance on Ocular Dryness Associated With Meibomian Gland Dysfunction
This study is a multicentric, comparative, randomized, investigator-blinded, in parallel groups study to demonstrate the non-inferiority of Neovis® Total Multi in comparison with Systane® Balance, in terms of improvement of…
- Trial name
- NCT05191771
- Testing
- Neovis Total Multi, Systane Balance
- Volunteers
- 120 people
- Sponsor
- Horus Pharma
MB
Mass Balance Study of [14C] Flonoltinib Maleate
The primary objectives are: 1. To investigate the total radioactivity in urine and feces after a single oral administration of [14C]Flonoltinib in healthy adult male participants, thereby obtaining human radioactive recovery…
- Trial name
- NCT07612306
- Testing
- Flonoltinib 75mg
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Chengdu Zenitar Biomedical Technology Co., Ltd
Healthy
Bioequivalence Study of Paricalcitol Capsules, 4 mcg Under Fasting Conditions
An open-label, balanced, randomized, two-treatment, two-sequence, two-period, single-dose, crossover oral bioequivalence study in healthy subjects under fasting conditions.
- Trial name
- NCT02322632
- Testing
- Paricalcitol Capsules, 4 mcg
- Where
- India
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Diabetes Mellitus, Hemodialysis Complication
Therapeutic Plantar Electrical Stimulation Intervention During Hemodialysis to Improve Balance and Mobility
A high prevalence of diabetes has been reported in Qatar with nearly 23% population suffering from the pandemic, thereby increasing the associated healthcare cost.
- Conditions
- Diabetes Mellitus, Hemodialysis Complication, Cardiovascular Complication, Quality of Life
- Trial name
- NCT05407207
- Testing
- Tennant Biomodulator ®
- Where
- 2 sites in United States, Qatar
- Volunteers
- 100 people
- Sponsor
- Hamad Medical Corporation
Healthy
Bioequivalence Study of Lamotrigine Extended-Release Tablets 200mg Under Fed Condition
This is an open label, randomised, balanced, two-treatment, two-period, two-sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01888263
- Testing
- Lamotrigine
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Volunteer
A Single Dose Study of Radiolabeled RO4602522 in Healthy Volunteers
This single-center, open-label study will investigate the pharmacokinetics and elimination of a radiolabelled dose of RO4602522 in healthy male volunteers. The healthy male volunteers will receive a single oral dose of RO4602522.
- Trial name
- NCT01631422
- Testing
- RO4602522
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche