Clinical trials: Bariatric Sleeve Gastrectomy
Morbid Obesity, Gastroesophageal Reflux
MGB/OAGB and LSG Effects on Lower Esophageal Sphincter (LES) Function
Background While several articles have reported about the effects of laparoscopic sleeve gastrectomy (LSG) on the lower esophageal sphincter (LES), to date, just one paper has discussed this issue with regard the Mini/One…
- Conditions
- Morbid Obesity, Gastroesophageal Reflux, Bariatric Surgery Candidate
- Trial name
- NCT02987673
- Testing
- MGB/OAGB, LSG
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Mario Musella MD
Nutritional Deficiency
Nutritional Deficiency After Bariatric Surgeries
comparing micro-nutrient deficiencies in postoperative morbid obese patients who will be undergoing gastric bypass and sleeve gastrectomy with regards to vit B 12, vitamin D,iron studies and calcium .
- Trial name
- NCT04717973
- Testing
- laboratory testing of CBC, serum ferritin, and vitamin B 12
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Portal Vein Thrombosis
Chances in Portal System Flow After Two Bariatric Procedures
Obesity if a health endemic problem over the entire world. Bariatric surgery is the best chance for those patients with morbid obesity to loss weight and to maintain the loosed weight.
- Trial name
- NCT02733770
- Testing
- Laparoscopic sleeve gastrectomy, Laparoscopic mini gastric bypass
- Where
- Israel
- Sponsor
- Assuta Medical Center
Morbid Obesity
Laparoscopic Adjustable Gastric Banding Versus Laparoscopic Sleeve Gastrectomy
The investigators aim to determine the clinical and metabolic outcomes of two available bariatric restrictive procedures: laparoscopic adjustable gastric banding (LAP-BAND) and laparoscopic sleeve gastrectomy for the treatment of…
- Trial name
- NCT00434655
- Testing
- Laparoscopic restrictive procedure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Morbid Obesity
Long-term Adverse Effects After Bariatric Surgery on Oesophagus Epithelium
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on oesophageal symptoms and disease, including the presence of Barrett oesophagus ≥ 5 years post-surgery.
- Trial name
- FUB-B (NCT03410849)
- Testing
- Gastroscopy
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- University Hospital, Basel, Switzerland
Bariatric Surgery Candidate, Obesity, Morbid
The Role of Extended Antral Resection on Weight Loss and Metabolic Response After Sleeve Gastrectomy
Aim: The impact of extended antral resection (AR) after laparoscopic sleeve gastrectomy (LSG) on weight loss changes and metabolic response is still not clearly elucidated with conflicting results.
- Trial name
- NCT04109664
- Testing
- laparoscopic sleeve gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Morbid Obesity, Metabolic Syndrome
The S.L.I.M.M.S. Procedure for Severe Clinical Obesity
Assessment of Gastric Bypass combined with Vertical Sleeve Gastrectomy as primary treatment for patients with severe clinical obesity.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Type2 Diabetes, Insulin Resistance
- Trial name
- SLIMMS (NCT04592601)
- Testing
- S.L.I.M.M.S. Procedure
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- The N.E.W. Program
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Weight Loss, Diabetic Gastroparesis
Potential Benefits of Sleeve Gastrectomy Surgery on Diabetic Gastroparesis Symptoms
The purpose of this registry is to evaluate if sleeve gastrectomy surgery will help with symptoms of delayed gastric emptying for patients suffering from diabetic gastroparesis.
- Conditions
- Weight Loss, Diabetic Gastroparesis, Bariatric Surgery Candidate, Sleeve Gastrectomy
- Trial name
- NCT03376399
- Testing
- Gastroparesis Cardinal Symptom Index Questionnaire
- Where
- United States
- Sponsor
- Baylor Research Institute
Obesity, Morbid, Weight Gain
Transit Bipartition After Sleeve Gastrectomy
Retrospective analysis of 100 morbidly obese patients who underwent a transit bipartition (TB) procedure ("Single Anastomosis Sleeve Ileal bypass") for inadequate weight loss or weight recidivism after a previous sleeve…
- Conditions
- Obesity, Morbid, Weight Gain, Bariatric Surgery Candidate
- Trial name
- TB-LSG (NCT04782648)
- Testing
- transit bipartition
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ruhr University of Bochum
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Cirrhosis is a form of advanced liver disease that can lead to serious complications, especially when combined with severe obesity.
- Conditions
- Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
- Trial name
- OPTIMAL (NCT07058155)
- Testing
- Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Bariatric Surgery Candidate
Short Term Outcome Of Distal Mesogastric Fixation After Laparoscopic Sleeve Gastrectomy;
This study included patients who were admitted to investigator's center to do laparoscopic sleeve gastrectomy . Cases were collected in the period from December 2019 to December 2020.
- Trial name
- NCT04834323
- Testing
- distal mesogastric fixation after sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Zagazig University
Morbid Obesity
Laparoscopic Sleeve Gastrectomy With and Without Omentectomy
The investigators aim to determine the clinical and metabolic effects of sleeve gastrectomy with or without omentectomy in the treatment of morbid obesity.
- Trial name
- NCT00434525
- Testing
- Laparoscopic restrictive procedure, Sleeve gastrectomy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- North Texas Veterans Healthcare System
Glucose Metabolism Disorders, Obesity
Effect of Meal Texture on Glucose-metabolism and Gut Hormone Response After Bariatric Surgery
The investigators want to evaluate the difference in glucose metabolism and intestinal hormonal response after a liquid meal versus a solid meal in patients after bariatric surgery.
- Conditions
- Glucose Metabolism Disorders, Obesity, Sleeve Gastrectomy, Gastric Bypass
- Trial name
- Obesity (NCT04082923)
- Testing
- Liquid meal, Solid meal
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Obesity &Amp; Overweight
The Impact of Probiotics on Bariatric Treatment Outcomes
The planned study aims to assess whether probiotics improve the quality of life in patients during the early postoperative period following sleeve gastrectomy, and whether they influence the absorption of micro- and…
- Trial name
- PROBE (NCT07258732)
- Testing
- Probiotic, Diet
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Obesity, Morbid, Obesity and Overweight
Identification of Pre-surgical Phenotypic Indicators Predictive of Quality of Life Trajectories in Obese Patients Following Bariatric Surgery
This study aims to identify pre-operative phenotypic determinants predictive of quality of life trajectories in post-bariatric surgery patients.
- Conditions
- Obesity, Morbid, Obesity and Overweight, Bariatric Surgery, Bariatric Surgery Patients
- Trial name
- PHENOBEQOL73 (NCT06951893)
- Testing
- Hospital Anxiety and Depression Scale, Dutch Eating Behaviour Questionnary, Impact of Weight on Quality Of Life
- Where
- France
- Volunteers
- 165 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Roux en Y Gastric Bypass, Sleeve Gastrectomy
Venlafaxine PK Following Bariatric Surgery
This study is being conducted to evaluate how the body absorbs and processes the immediate release (IR) and sustained release (XR) medication venlafaxine (Effexor®).
- Trial name
- VLX (NCT02005107)
- Testing
- Venlafaxine IR and Venlafaxine XR
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- North Dakota State University
Obesity
Weight Loss With Intensive Lifestyle Modifications Plus Bariatric Surgery Versus Liraglutide 3 mg
Background/Objectives: Only 1% of the clinically eligible subjects receive surgical treatment for their obesity, thus other options should be investigated.
- Trial name
- LETHE (NCT03534310)
- Testing
- LIRAGLUTIDE 3 Mg/0.5 mL (18 Mg/3 mL) SUB-Q PEN INJECTOR (ML), lifestyle modification, sleeve gastrectomy
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Catholic University of the Sacred Heart
Obesity, Bariatric Surgery Candidate
Evaluation of Hormonal Contraceptive Treatments in Obese Women
The aim of our study is to assess the concentrations of different oral contraceptive agents in morbid obese women before and after two types of bariatric surgeries (RYGB and sleeve gastrectomy) in order to study the role of the…
- Conditions
- Obesity, Bariatric Surgery Candidate, Oral Contraceptive
- Trial name
- OBECO (NCT02398903)
- Testing
- Blood samples for measurement of drug Css, DXA and impedancemetry
- Where
- 2 sites in France
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity
Enhanced Recovery After Surgery in Laparoscopic Sleeve Gastrectomy
While laparoscopic sleeve gastrectomy (LSG) has become the most commonly performed bariatric surgery procedure in the US and worldwide, it is associated with significant postoperative nausea and vomiting (PONV), which can lead to…
- Trial name
- NCT03520803
- Testing
- Enhanced recovery after surgery protocol
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Hartford Hospital