Clinical trials: Bariatric Sleeve Gastrectomy
Obesity
Exendin-9,39 and Satiety After Bariatric Surgery
The overall aim of the application is to determine the contribution of the elevated incretin hormone concentrations seen after certain types of bariatric surgery to the regulation of food intake and satiety.
- Trial name
- NCT02779075
- Testing
- Saline, Exendin-9,39
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Morbid Obesity, Metabolic Syndrome X
Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Bariatric surgery is the most effective treatment for morbid obesity. Roux-en-Y gastric bypass (RYGB) is a bariatric procedure with known safety and effectiveness.
- Conditions
- Morbid Obesity, Metabolic Syndrome X, Diabetes Mellitus, Dyslipidemia
- Trial name
- NCT01806506
- Testing
- Laparoscopic sleeve gastrectomy, Roux-en-Y Gastric Bypass
- Where
- Poland
- Volunteers
- 72 people
- Sponsor
- Medical University of Warsaw
Obesity, Status Post Sleeve Gastrectomy
Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Background: Metabolic Bariatric Surgery, including a surgery called vertical sleeve gastrectomy, is the most effective weight loss treatment for severe obesity.
- Trial name
- NCT04883346
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Bariatric Surgery Candidate, Bone Loss
Healthy Body, Healthy Bones After Bariatric Surgery Trial
One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Bone Resorption
- Trial name
- NCT04279392
- Testing
- Zoledronic Acid 5 mg/Bag 100 ml Inj
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Morbid Obesity, High BMI
Efficacy Of Quadratus Lumborum II Block For Laparoscopic Sleeve Gastrectomy
The QL 2 block is a novel fascial plane block recently described by Blanco and colleagues in which local anesthetic is deposited adjacent to the antero-lateral aspect of the quadratus lumborum muscle.
- Trial name
- NCT04073056
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Diabetes Mellitus, Type 2
Longitudinal Phenotyping of Bariatric Surgery Patients
Recent studies have shown that bacteria within the gut play an important role in diabetes improvement after bariatric (weight-loss) surgery.
- Trial name
- NCT02421055
- Testing
- Laparoscopic Roux-en-Y Gastric Bypass, Laparoscopic Sleeve Gastrectomy
- Where
- United Kingdom
- Volunteers
- 158 people
- Sponsor
- Imperial College London
Bariatric Surgery Candidate, Pain, Postoperative
The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery
This study is prospective, randomized trial in which the efficacy of liposomal bupivacaine (Exparel®) is compared to standard bupivacaine local surgical site injection in reducing total IV and oral morphine equivalents required…
- Trial name
- Exparel (NCT03196505)
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Morbid Obesity
Taste Perception Pre and Post Bariatric Surgery
The investigators wish to study the effects of three forms of bariatric surgery, gastric bypass lap banding, and sleeve gastrectomy. The surgery is not part of the clinical trial.
- Trial name
- RBtaste (NCT01536197)
- Testing
- Gastric bypass, Gastric banding, Sleeve gastrectomy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
Morbid Obesity
Sonographic Evaluation of Visceral Fat After Bariatric Surgery
Excess visceral fat is a key factor in the development of metabolic syndrome associated with obesity. After bariatric surgery, patients experience weight loss accompanied by a decrease in the amount of total body fat.
- Trial name
- NCT01285791
- Where
- Israel
- Volunteers
- 39 people
- Sponsor
- Hadassah Medical Organization
Bariatric Surgery Candidate
Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery
This study evaluates whether zoledronic acid can prevent the high bone turnover that occurs after Roux-en-Y Gastric Bypass (RYGB) and sleeve gastrectomy (SG) surgery.
- Trial name
- NCT03424239
- Testing
- Zoledronic Acid, Calcium citrate + vitamin D, Vitamin D3
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Gastrectomy, Obesity
Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy
This study aims to compare the difference in staple usage and post-operative GERD (heartburn) between patients that had an endoscope used versus patients that had a suction calibration system used on them during "laparoscopic…
- Trial name
- NCT03939819
- Testing
- ViSiGi® 3D suction calibration device, Esophagogastroduodenoscopy (EGD) calibration
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Emory University
Obesity
Prospective, Double Blind, Placebo Control, Bariatric IV Ace
The purpose of this study is to determine if the administration of acetaminophen given intravenously (through an IV) beginning during surgery and then for 3 additional doses during the first 24 hours post-operatively will reduce…
- Trial name
- Bariatricace (NCT02452320)
- Testing
- intravenous acetaminophen
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Weill Medical College of Cornell University
Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Bariatric surgery remains the most effective therapy for obesity. Postoperative nausea and vomiting (PONV) are commonly reported following bariatric surgery.
- Trial name
- NCT03435003
- Testing
- Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Obesity
Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy
Observational studies suggest that bariatric surgery is the most effective intervention for weight loss. Comparative effectiveness of Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) demonstrate that RYGB is…
- Trial name
- NCT03115424
- Testing
- Saxenda, RYGB
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic