Clinical trials: Bariatric Surgery, open to volunteers
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Obesity & Overweight, Bariatric Surgery
Rosuvastatin and Losartan Pharmacokinetics After Bariatric Surgery
This prospective, open-label, non-randomized pharmacokinetic study will evaluate how Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy affect systemic exposure to single oral test doses of rosuvastatin and losartan.
- Conditions
- Obesity & Overweight, Bariatric Surgery, Pharmacokinetics After Oral Intake, Drug Absorption
- Trial name
- BARI-PK (NCT07748273)
- Testing
- Rosuvastatin, Losartan (Control)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital das Clínicas de Ribeirão Preto
Obesity & Overweight, Gastroesophageal Reflux (GERD)
Transit Bipartition After Sleeve Gastrectomy
This prospective, single-center study will evaluate adults undergoing revisional conversion from sleeve gastrectomy to intestinal transit bipartition.
- Conditions
- Obesity & Overweight, Gastroesophageal Reflux (GERD), Weight Recurrence, Bariatric Surgery
- Trial name
- BTT-SLEEVE (NCT07728682)
- Testing
- Conversion to Intestinal Transit Bipartition
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital das Clínicas de Ribeirão Preto
Bariatric Surgery Candidate, Pain, Postoperative
Autonomic Neural Blockade in Bariatric Surgery
The purpose of this research is to evaluate if autonomic nerve block (ANB- blocking pain and nausea signals) decreases pain and anti-nausea medication requirements as well as the experience of pain/nausea during the first 72…
- Conditions
- Bariatric Surgery Candidate, Pain, Postoperative, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT07104825
- Testing
- Intraoperative autonomic neural blockade (ANB), Laparoscopic Standard of Care Abdominal Wall Block
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Endeavor Health
Obesity (BMI > 35), Bariatric Surgery
Digital Follow-Up and Nursing Education in Bariatric Surgery Patients
This randomized controlled experimental study aims to evaluate the effect of a PHP-MySQL database-based digital follow-up system combined with structured nursing education on quality of life, body mass index (BMI), and exercise…
- Trial name
- DigiBarQoL (NCT07457034)
- Testing
- Structured Nursing Education and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Okan University
Thirst in Bariatric Surgery Patients
The Effects of Menthol and Cold Spray Applications on Thirst and Comfort in Bariatric Surgery
Bariatric surgery is a widely used surgical treatment method in obesity management that improves quality of life and provides long-term weight loss. Patients often experience thirst in the early postoperative period.
- Trial name
- NCT07728500
- Testing
- Menthol Group, Cold Spray Group
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Atlas University
Obesity, Sarcopenia
Sarcopenia Indicators After Bariatric Surgery
This prospective observational study aims to evaluate longitudinal changes in sarcopenia-related parameters in patients undergoing bariatric surgery.
- Conditions
- Obesity, Sarcopenia, Bariatric Surgery
- Trial name
- NCT07717333
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hatice Zehra FERHATLAR
Obesity, Bariatric Surgery Candidate
Effect of Patient Education on Drinking Behaviour and Oral Hygiene in Patients Undergoing Bariatric Surgery
The background for the study is that many bariatric surgery patients struggle with their oral health after bariatric surgery. This is probably related to both physiological changes and changes in eating and drinking patterns.
- Trial name
- BAR-VANNTANN (NCT06617689)
- Testing
- Various levels of patient education
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- St. Olavs Hospital
Gallstone Disease, Bariatric Surgery
ABCG8, UGT1A1 and Gallstone Disease After Bariatric Surgery
The goal of this observational genetic case-control study is to learn whether two specific genetic variants in ABCG8 and UGT1A1 are associated with gallstone disease after bariatric surgery.
- Conditions
- Gallstone Disease, Bariatric Surgery, Metabolic Surgery, Cholecystectomy
- Trial name
- NCT07702630
- Testing
- blood sampling
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Obesity, Bariatric Surgery
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
- Conditions
- Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
- Trial name
- INNOVATE-VSG (NCT06783751)
- Testing
- Modified Vertical Sleeve Gastrectomy (mVSG), Conventional Vertical Sleeve Gastrectomy (cVSG)
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of California, Irvine
Bariatric Surgery Patients
The Metabolic and Genetic Drivers of Body Composition Changes Following Weight Loss Surgery
Weight loss surgery is very good at reducing body weight but it can also cause the loss of both muscle and strength. Some patients undergoing weight loss surgery do not achieve their weight loss goals and regain the weight they…
- Trial name
- NCT07178704
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Bariatric Surgery, Bariatric Sleeve Gastrectomy
Effects of the Dietary Inflammatory Index on Systemic Inflammation Markers and Gastrointestinal Symptoms in Individuals With Bariatric Surgery
The goal of this observational cross-sectional study is to evaluate the relationships between the Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms in adults aged 18-65 who have…
- Conditions
- Bariatric Surgery, Bariatric Sleeve Gastrectomy, Inflamation, Systemic Inflammation
- Trial name
- NCT07293624
- Testing
- Observational Intervention, Observetional
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Bilgi University
Obesity, Smoking Cessation
A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
The purpose of this research study is to evaluate a multiple health behavior change intervention for weight loss and smoking cessation using medication (Naltrexone + Bupropion) and behavior therapy in adults seeking bariatric…
- Conditions
- Obesity, Smoking Cessation, Bariatric Surgery Patients
- Trial name
- NCT07398404
- Testing
- Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Medical University of South Carolina
Obesity (Disorder), Obesity & Overweight
Dramatherapy for Psychological and Social Well-Being in Obesity and Bariatric Care
Obesity is currently a major public health challenge in France, particularly in the Hauts-de-France region, where prevalence exceeds 20% of the adult population.
- Conditions
- Obesity (Disorder), Obesity & Overweight, Eating Disorders, Bariatric Surgery
- Trial name
- NCT07685483
- Testing
- Adapted Physical Activity, Dramatherapy
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Universite du Littoral Cote d'Opale
Bariatric Surgery Candidate, Obesity
Periodontal Assessment of a Bariatric Care Population
Our primary aim is to investigate the prevalence and severity of Periodonotal Disease (PD) in a population of obese patients. Our secondary objectives are to: Investigate inflammatory biomarkers that have been associated with PD…
- Trial name
- Bariatric (NCT04851470)
- Where
- 4 sites in United Kingdom
- Volunteers
- 394 people
- Sponsor
- Queen Mary University of London
Obesity & Overweight, Bariatric Surgery
Time-Restricted Eating After Bariatric Surgery
This study aims to compare the effects of time-restricted eating (TRE, 16/8) in adults with obesity who have and have not undergone bariatric surgery (BS).
- Conditions
- Obesity & Overweight, Bariatric Surgery, Weight Regain, Weight Regain Post Bariatric Surgery
- Trial name
- NCT07672821
- Testing
- Time-Restricted Eating (16:8)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Obesity (Disorder), Body Image
3D Reconstruction, VR and Machine Learning in Body Image in Bariatrics
Studies have shown that following bariatric metabolic surgery (BMS), patients continue to experience dissatisfaction with their new body image and identity).
- Conditions
- Obesity (Disorder), Body Image, Mental Health, Bariatric Surgery
- Trial name
- NCT07668492
- Testing
- Body Image Counselling with Virtual Reality
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Imperial College London
Obesity, Morbid, Bariatric Surgery Candidate
Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery
The aim of this cohort is to evaluate the follow-up of morbidly obese patients treated by several types of bariatric procedures.
- Trial name
- BAREVAL (NCT02310178)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Montpellier
Obesity, Morbid, Bariatric Surgery
Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity…
- Conditions
- Obesity, Morbid, Bariatric Surgery, Intestinal Permeability, Gastrointestinal Symptoms
- Trial name
- METABAR (NCT07643376)
- Testing
- Clinical and Biochemical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University