Clinical trials: Bariatric Surgery, open to volunteers
Obesity, Abdominal, Diabetes
Exploratory Evaluation of the Effect of Cholestyramine on Serum Levels of POPs in Obese Female Patients
Environmental endocrine disruptors (EDCs) represent a major problem for human health.Some PEEs can accumulate in the fatty tissue of the human body thanks to their lipophilic nature, and are known as persistent organic pollutants…
- Conditions
- Obesity, Abdominal, Diabetes, Bariatric Surgery Candidate
- Trial name
- OBESE (NCT05966727)
- Testing
- Cholestyramine Powder
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Weight Regain Post Bariatric Surgery, Obesity (Disorder)
Naltrexone/Bupropion With or Without Very Low Calorie Ketogenic Diet for Weight Regain After Bariatric Surgery
The goal of this clinical trial is to evaluate the superiority of combined VLCKD, intensive lifestyle intervention and naltrexone/bupropion (N/B) versus standard of care with naltrexone/bupropion on weight loss for people with…
- Trial name
- Relay (NCT06881485)
- Testing
- Very Low Calorie Diet
- Where
- 2 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Endometrial Cancer, Atypical Hyperplasia
Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometrium
A growing population of young women with obesity are developing atypical hyperplasia (pre-cancer) and endometrial cancer. Progestin is the standard treatment for women who wish to preserve fertility, but this approach does not…
- Conditions
- Endometrial Cancer, Atypical Hyperplasia, Bariatric Surgery Candidate
- Trial name
- B-FiERCE (NCT04008563)
- Testing
- Bariatric Surgery
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Gastric Emptying, Bariatric Surgery
Reference Values for Gastric Emptying Scintigraphy After Bariatric Surgery
Oesophageal and gastric scintigraphy evaluates the function of the gastrointestinal system including variables such as oesophageal transit and gastric emptying (GE). Some variables are known to change after bariatric surgery.
- Trial name
- SCATTER (NCT06391255)
- Testing
- scintigraphy
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Obesity and Overweight, Bariatric Surgery (Gastric Bypass)
Protein Requirements After Bariatric Surgery
The study investigates protein requirements at least 1 year after gastric bypass surgery in adult males, to investigate whether protein requirements are elevated compared to protein requiremens for the general populaiotn.
- Conditions
- Obesity and Overweight, Bariatric Surgery (Gastric Bypass), Protein Requirement
- Trial name
- PROXY (NCT06853652)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bariatric Surgery Candidate, Ketogenic Dieting
Ketogenic Diet Prior to Bariatric Surgery
Standard dietary regiments for bariatric are advised prior to surgery. The most used diet is a very low calorie diet (VLCD). These diets potentially have multiple pittfalls.
- Trial name
- NCT06850493
- Testing
- VLCKD (ketogenic diet), VLCD (Very-low-calorie-diet)
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Mechanical Ventilation Pressure High, Bariatric Surgery Candidate
Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome).
- Trial name
- NCT06168162
- Testing
- titated PEEP to best static compliance
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Bariatric Surgery, Type 2 Diabetes
Fecal Microbiota Transfer to Improve Diabetes Control Post-bariatric Surgery
Obesity progresses worldwide with few effective treatments leading to a burst in Bariatric surgery (BS). France is the 3rd country in BS numbers yearly.
- Trial name
- DRIFTER (NCT06192693)
- Testing
- Capsulized fecal microbiota transfer containing the healthy feces + stool dilution solution
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Metabolic Syndrome, Severe Obesity
Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.
The aim of this study is to determine the feasibility and effectiveness of endoscopic anastomosis of sleeve gastrectomy to ileum with a lumen apposing metal stent (LAMS) after a failed sleeve gastrectomy.
- Conditions
- Metabolic Syndrome, Severe Obesity, Reflux, Gastroesophageal, Bariatric Surgery
- Trial name
- NCT06757296
- Testing
- Endoscopic SASI
- Where
- 3 sites in Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore Health Services
Bariatric Surgery, Hypertension
Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension
The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.
- Trial name
- NCT05166954
- Testing
- LSG, RYGB
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Friendship Hospital
Chronic Pain, Widespread, Obesity
Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults
The goal of this observational study is to learn if surgical weight loss can improve chronic widespread pain in people living with higher BMI who self-identify as Hispanic/Latino ethnicity or non-Hispanic Black based on the…
- Conditions
- Chronic Pain, Widespread, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT06795386
- Testing
- Bariatric Surgery
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- New York University
Bariatric Surgery
Comparison of the Effect of Cyclizine Versus Metoclopramide on Gastric Residual Volume in Patients Undergoing Bariatric Surgery: A Randomized Double-blinded Clinical Trial
The aim of this work is to compare the effects metoclopramide versus Cyclizine withing the context of multimodal antiemetic strategy on GRV in patients scheduled for bariatric surgery.
- Trial name
- NCT06789614
- Testing
- intravenous CYCLIZINE ,Metaclopromide
- Volunteers
- 76 people
- Sponsor
- Cairo University
Obesity, Metabolic Disease
Conventional Vs Tailored Limb Lengths in Laparoscopic Roux-en Y Gastric Bypass Surgery
The study aims to investigate whether tailoring limb lengths based on the 1/3rd and 2/3rd concept improves clinical outcomes in Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) surgery compared to conventional limb lengths.
- Conditions
- Obesity, Metabolic Disease, Bariatric Surgery Candidate, Metabolic Surgery
- Trial name
- TAILO-R-YGB (NCT06756789)
- Testing
- Laparoscopic Roux-en Y Gastric bypass (RYGB)- Conventional approach, Laparoscopic Roux-en Y Gastric bypass (RYGB)- Tailored approach
- Where
- India
- Volunteers
- 40 people
- Sponsor
- GEM Hospital & Research Center
Liver Retraction During Bariatric Surgery
Organ Retractor Device Study
This study aims to assess the safety and efficacy of an organ retraction device. The study is low risk as it is only being used in patients already undergoing primary robotic bariatric surgery.
- Trial name
- NCT06754514
- Testing
- liver retraction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Boehringer Labs LLC
Bariatric Surgery
Monitoring Changes in Endotracheal Tube Cuff Pressure During Laparoscopic Bariatric Surgery
This prospective observational cohort study was designed to assess the relationship between ETT cuff pressures and airway pressures in obese patients undergoing laparoscopic bariatric surgery.
- Trial name
- NCT06738875
- Testing
- manometre
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Bariatric Surgery, Postoperative Complications
National Emergency Bariatric Surgery Audit
The goal of this observational study is to investigate the incidence, management, and outcomes of complications following bariatric surgery in patients in the United Kingdom.
- Conditions
- Bariatric Surgery, Postoperative Complications, Emergencies, Surgical Procedures, Operative
- Trial name
- NEBSA (NCT06738004)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Bedfordshire Hospitals NHS Foundation Trust
Obesity, Type2diabetes
Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Obesity and Type 2 diabetes mellitus (DMT2) are two of the most common chronic diseases of the Western society. Obesity is one critical factor in DMT2 development, with weight loss having profound beneficial effects on DMT2 and…
- Conditions
- Obesity, Type2diabetes, Bariatric Surgery Candidate, Metabolic Disease
- Trial name
- BEOD (NCT05859022)
- Testing
- Roux-en-Y gastric By-pass (RYGB) surgery, Bariatric Arterial Embolization (BAE) procedure
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Obesity, Bariatric Surgery Candidate
Exploring the Effects of Obesity and Bariatric Surgery on the Brain Using Magnetic Resonance Imaging
Background and Purpose: The causes of obesity are highly complex, with eating behaviors playing a crucial role. Current research indicates that many brain regions are involved in the regulation of appetite, eating behaviors, and…
- Trial name
- NCT06708117
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Bariatric Surgery, Acute Kidney Injury
Post Bariatric Surgery Acute Kidney Injury: Incidence and Risk Factors
Bariatric surgery is the most effective means of inducing and maintaining sustained weight loss. Apart from the weight loss effect, bariatric surgery leads to the remission of chronic metabolic disorders such as type 2 diabetes…
- Trial name
- NCT06697743
- Volunteers
- 30 people
- Sponsor
- Georgina Tharwat Abdelmasih
Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes
The Role of Nutrition in Muscle Function of Bariatric Surgery Patients
Current recommendations for protein intake after bariatric surgery are not based on strong scientific evidence. It remains unclear how much protein should be eaten to minimize muscle loss and preserve the metabolism and function…
- Conditions
- Obesity, Diabetes, Nutrition, Physical Health, Body Composition Changes, Muscle Function, Handgrip Strength Test, Protein Metabolism
- Trial name
- NCT06680492
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal