Clinical trials: Baroreflex
Hypertension
Rheos® Pivotal Trial
The purpose of this clinical trial is to demonstrate the efficacy and safety of the Rheos system in subjects with hypertension that are resistant to treatment with at least three anti-hypertension agents, one of which is a…
- Trial name
- NCT00442286
- Testing
- Rheos® Baroreflex Hypertension System
- Where
- 44 sites in United States, Germany and 1 more
- Volunteers
- 591 people
- Sponsor
- CVRx, Inc.
Arteriosclerosis Obliterans
Preoperative Heart Rate Variability and Baroreflex Sensitivity in ASO Patients During Various Sleep Stages
The goal of this study is to evaluate the possible preoperative predictive value of altered heart rate variability (HRV) and baroreflex sensitivity in different sleep stages for postoperative adverse cardiac events (i.e.
- Trial name
- Barosleep (NCT00712946)
- Where
- Finland
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Hypertension
Rheos Feasibility Trial
The Rheos Feasibility Trial is designed to assess safety, device performance, and protocol parameters of the CVRx Rheos Baroreflex Therapy in patients with severe hypertension that are refractory to full drug therapy.
- Trial name
- NCT01077180
- Testing
- Implantation of the Rheos System, Standard of care medical management
- Volunteers
- 16 people
- Sponsor
- CVRx, Inc.
Heart Failure
Baroreflex Activation Therapy in Heart Failure
The purpose of this clinical investigation is to evaluate the efficacy and safety of the CVRx Barostim Neo System in the treatment of patients with heart failure.
- Trial name
- NCT01484288
- Testing
- Barostim Neo System
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- CVRx, Inc.
Hypertension
Device Based Therapy in Hypertension Trial
The purpose of this study is to demonstrate the safety and efficacy of the Rheos Baroreflex Hypertension Therapy System in patients with refractory hypertension.
- Trial name
- DEBuT-HT (NCT00710190)
- Testing
- Rheos Baroreflex Hypertension Therapy System
- Where
- 9 sites in Czechia, Germany and 4 more
- Volunteers
- 46 people
- Sponsor
- CVRx, Inc.
Heart Failure
Baroreflex Activation Therapy for Heart Failure
The purpose of this clinical trial (NCT02627196) is to develop valid scientific evidence for safety and effectiveness of Baroreflex Activation Therapy with the BAROSTIM NEO System in subjects with heart failure, defined as New…
- Trial name
- BeAT-HF (NCT02627196)
- Testing
- BAROSTIM NEO® System, Medical Management
- Where
- 92 sites in United States, United Kingdom
- Volunteers
- 1,090 people
- Sponsor
- CVRx, Inc.
Sympathetic Nervous System
Sympathetic Neural Outflow During Xenon Anesthesia in Humans
The purpose of this study is to test the hypothesis that sympathetic neural outflow to muscles as well as a sympathetic baroreflexes are not altered during xenon anesthesia in Healthy Volunteers.
- Trial name
- NCT01043419
- Testing
- xenon
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Air Liquide Santé International