Clinical trials: Basal Cell Cancer
Basal Cell Nevus Syndrome, Skin Neoplasm
A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma
The study evaluates whether ASN-002 is safe and effective in the treatment of nodular basal cell carcinoma (nBCC) in patients aged 18 years or over.
- Conditions
- Basal Cell Nevus Syndrome, Skin Neoplasm, Nodular Basal Cell Carcinoma of Skin
- Trial name
- ASN-002-001 (NCT02550678)
- Testing
- ASN-002, 5-FU
- Where
- 4 sites in Australia
- Volunteers
- 16 people
- Sponsor
- Ascend Biopharmaceuticals Ltd
Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults
Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
RATIONALE: Tests that measure how much saliva is made, hearing, swallowing, voice function, and quality of life may improve the ability to plan treatment for patients with advanced head and neck cancer and may help doctors find…
- Conditions
- Head and Neck Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Oral Complications of Radiation Therapy, Radiation Toxicity
- Trial name
- NCT00415025
- Testing
- adjuvant therapy, management of therapy complications, quality-of-life assessment
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Skin Cancer, Basal Cell Carcinoma
Autologous Patch Healing vs. Secondary Intention Healing After Mohs Micrographic Surgery
The primary objects of this study is to explore the potential effect of the autologous patch to optimize wound healing after skin cancer surgery with Mohs micrographic surgery (MMS) in the face in a randomized controlled trial…
- Trial name
- NCT05170035
- Testing
- MMS + Autologous patch, MMS and secondary intention healing
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Bispebjerg Hospital
Basal Cell Carcinoma
Intron-A/Aldara Combination Therapy for Basal Cell Carcinoma (BCC)
A trial to see if BCC excluding the scalp and face can be treated successfully with a combination therapy of Intron-A and Aldara.
- Trial name
- NCT00581425
- Testing
- Imiquimod and Interferon alpha
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- The University of Texas Health Science Center, Houston
Adenocarcinoma, Basal Cell Carcinoma
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
This is a pilot clinical trial determining the effect of a Methionine-reduced diet on serum levels in subjects with solid tumors. These are subjects who will receive systemic standard of care cancer therapy.
- Conditions
- Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Transitional Cell Carcinoma
- Trial name
- NCT07628634
- Testing
- Methionine-Reduced Diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Irvine
Solid Tumors With PTCH1 Loss-of-function Mutations
A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations
This study employs a 2-stage design that aims to evaluate the efficacy and safety of ENV- 101, a potent Hedgehog (Hh) pathway inhibitor, in patients with refractory advanced solid tumors characterized by loss of function (LOF)…
- Trial name
- NCT05199584
- Testing
- ENV-101 (taladegib)
- Where
- 16 sites in United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Biomedicines, Inc.
Basal Cell Carcinoma
Comparison of Two Schemes of Cryosurgery and Imiquimod Combination Treatment for Basal Cell Carcinoma
To compare the effectiveness of two application schemes of cryosurgery during a 5 week course of topical imiquimod i.e. cryosurgery at the end of the second week of imiquimod followed by 3 more weeks of imiquimod…
- Trial name
- IMCXvsCIMT (NCT01212549)
- Testing
- Immunocryosurgery, Cryoimmunotherapy
- Where
- Greece
- Volunteers
- 14 people
- Sponsor
- University of Ioannina
Non-Melanomatous Skin Cancer
Low Fat Diet to Prevent Disease Progression in Patients With Skin Cancer
RATIONALE: A low-fat, balanced diet may prevent disease progression in patients with nonmelanomatous skin cancer. PURPOSE: Randomized phase II trial to study the effectiveness of a low-fat, balanced diet to prevent disease…
- Trial name
- NCT00003097
- Testing
- preventative dietary intervention
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Baylor College of Medicine
Basal Cell Carcinoma (BCC)
Intralesional Cryosurgery for Basal Cell Carcinoma - a Feasibility Study
A feasibility study for the treatment of Basal Cell Carcinoma of the lower extremities in the elderly utilizing intralesional cryosurgery.
- Trial name
- NCT01633515
- Testing
- Intralesional cryotherapy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Carmel Medical Center
Non-Small Cell Lung Cancer (NSCLC), Basal Cell Carcinoma (BCC)
Expanded Access Use of Cemiplimab in Patients With Solid Tumors
Provide expanded access of cemiplimab in patients with solid tumors
- Conditions
- Non-Small Cell Lung Cancer (NSCLC), Basal Cell Carcinoma (BCC), Cutaneous Squamous Cell Carcinoma (CSCC)
- Trial name
- NCT06132191
- Testing
- Cemiplimab
- Sponsor
- Regeneron Pharmaceuticals
Head and Neck Cancer, Mucositis Oral
GM-CSF Mouthwash for Preventing and Treating Mucositis in Patients Undergoing Radiation Therapy for Head and Neck Cancer
GM-CSF may protect normal cells from the side effects, such as mucositis, of radiation therapy and may help damaged tissue heal faster after radiation therapy.
- Conditions
- Head and Neck Cancer, Mucositis Oral, Radiation Toxicity, Tongue Cancer
- Trial name
- NCT00293462
- Testing
- sargramostim, oral salt and soda mouthwash
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Marilyn Dodd
Basal Cell Carcinoma
A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma
This randomized, double-blind, placebo-controlled study will assess the efficacy and safety of vismodegib with surgery in participants with basal cell carcinoma.
- Trial name
- NCT01898598
- Testing
- Vismodegib
- Where
- 21 sites in United States
- Volunteers
- 18 people
- Sponsor
- Hoffmann-La Roche
Ovarian Cancer, Basal Cell Carcinoma
A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study
This was a multicenter, open-label extension study. Patients who received vismodegib (GDC-0449) in a Genentech-sponsored study and who had completed the parent study or who continued to receive vismodegib at the time the parent…
- Conditions
- Ovarian Cancer, Basal Cell Carcinoma, Metastatic Colorectal Cancer
- Trial name
- NCT00959647
- Testing
- Vismodegib, FOLFOX, FOLFIRI
- Where
- 10 sites in United States
- Volunteers
- 19 people
- Sponsor
- Genentech, Inc.
Skin Cancer, Melanoma (Skin Cancer)
Digital Phenotyping of Psychological Distress in Skin Cancer Patients
This prospective observational study enrolls 500 skin cancer patients across five Chinese tertiary care centers. The investigators use natural language processing and a hierarchical transformer model to analyse 1.2 million social…
- Conditions
- Skin Cancer, Melanoma (Skin Cancer), Squamous Cell Carcinoma Head and Neck Cancer (HNSCC), Basal Cell Carcinoma of Skin
- Trial name
- DP-SKIN (NCT07670403)
- Where
- China
- Sponsor
- West China Hospital
Basal Cell Carcinoma
Study Evaluating the Interest of Vismodegib as Neo-adjuvant Treatment of Basal Cell Carcinoma (BCC)
Open-label, non-comparative, multicenter, phase II study of Vismodegib in patients with locally advanced BCC.
- Trial name
- VISMONEO (NCT02667574)
- Testing
- ERIVEDGE
- Where
- 17 sites in France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Lille
Basal Cell Carcinoma
Observational Study of Correlation Between Recurrent Basal Cell Carcinoma and Localisation
.During one year all the resected basal cell carcinomas (BCC) analyzed in Montpellier University Hospital Anatomopathology unit were included in this study. Localisation and histological characteristics were collected.
- Trial name
- NCT04795297
- Where
- France
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Basal Cell Carcinoma
Evaluation of Efficacy of Photodynamic Therapy in Basal Cell Carcinoma
The purpose of this study is to evaluate the efficacy of pdt in treatment of bcc and factors that affect response rate.
- Trial name
- NCT00985829
- Testing
- photodynamic therapy
- Volunteers
- 28 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Basal Cell Carcinoma
Vismodegib for Treatment of Basal Cell Carcinoma
The primary objectives of this study are to assess, using Mohs micrographic surgery (MMS) at the end of treatment, the efficacy (primary) and safety (secondary) of vismodegib compared to placebo in the oral adjunctive pre…
- Trial name
- Erivedge (NCT01543581)
- Testing
- Vismodegib
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Abel Torres, MD
Basal Cell Carcinoma, Squamous Cell Carcinoma Skin
Skin Cancer and Hyperthermia and Radiotherapy
The SAHARA trial assesses wether combining ultrahypofractionated accelerated radiotherapy (RT) with hyperthermia is as effective as standard hypofractionated high-dose radiation in treating non-melanoma skin cancer (NMSC).
- Conditions
- Basal Cell Carcinoma, Squamous Cell Carcinoma Skin, Non-melanoma Skin Cancer
- Trial name
- SAHARA (NCT06384053)
- Testing
- Water-filtered infrared-A-hyperthermia (wIRA) hyperthermia combined, Radiotherapy (RT)
- Where
- 4 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Kantonsspital Winterthur KSW