Clinical trials: Basic Science
Healthy
Evaluation of Four Different Dosing Regimens of Cross-Linked Polyelectrolyte (CLP) in Healthy Volunteers
This is a study to determine the effect of four different dosing regimens of CLP in normal healthy volunteers.
- Trial name
- NCT02079233
- Testing
- Cross-Linked Polyelectrolyte (CLP)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sorbent Therapeutics
Episodic Memory
Episodic Memory Integration and Interference
The purpose of this study is to assess how emotional memories integrate and interfere with one another over time. We will be using a multi-session experimental paradigm consisting of two encoding sessions and one retrieval…
- Trial name
- NCT05974371
- Testing
- emotional context similarity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Boston College
Burnout, Professional, Resilience, Psychological
Web-based Implementation for the Science of Enhancing Resilience Study
Resilience means a healthcare provider's ability to cope, recover, and learn from stressful events, as well as their access to resources that promote health and well-being.
- Trial name
- WISER (NCT02603133)
- Testing
- Three Good Things, Gratitude, Random Acts of Kindess
- Where
- 9 sites in United States
- Volunteers
- 2,650 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mindfulness, Psychological Distress
Brief Mindfulness-Based Intervention to Reduce Psychological Distress in Health Sciences Students
This project aims to evaluate the effectiveness of a brief mindfulness-based intervention in reducing psychological distress among first-year health sciences students at the Universidad Nacional Mayor de San Marcos.
- Trial name
- NCT06777407
- Testing
- Brief Mindfulness-Based Intervention to Reduce Psychological Distress, Psychoeducational brochure
- Where
- Peru
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University of San Marcos, Peru
Physiotherapy
Scientific Content Disseminated Via Social Media for Physiotherapists
This study is designed to assess how effective social media is in disseminating scientific knowledge to physiotherapists in Brazil.
- Trial name
- ASTEROID (NCT06605040)
- Testing
- Dissemination via Social Media, Dissemination via Email
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Universidade Federal de Santa Maria
Opioid Use Disorder
MBC2OTP Project (Measurement-Based Care Implementation in Community Opioid Treatment Programs)
The goal of this clinical trial is to evaluate the effectiveness and implementation of measurement-based care, which involves the systematic use of client self-report data to inform and enhance treatment, in opioid treatment…
- Trial name
- MBC2OTP (NCT06345274)
- Testing
- Measurement Based Care Training and Monthly Consultation
- Where
- 5 sites in United States
- Volunteers
- 35 people
- Sponsor
- Northwestern University
Depression, Hypertension
Community-based Approach to Lowering Stress Through Mindfulness
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression.
- Trial name
- CALM-Chicago (NCT06987799)
- Testing
- Mindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Implementation Science, Transportation of Patients
Implementation Study of Intra-hospital Transfer of Pediatric Inpatients
This study implemented the "Clinical Practice Guidelines for In-hospital Transfer of Pediatric Inpatients (2023 edition)" released by the research team in June 2023 in real clinical settings.
- Trial name
- NCT06512805
- Testing
- Routine transport, Post-guideline transfer
- Where
- China
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Cancer, Exercise
From Exercise Oncology Research to Clinical Practice
Building on previous research that shows the benefits of exercise, this study aims to find out how best to implement exercise in real-world settings.
- Conditions
- Cancer, Exercise, Implementation of Evidence Based Programs, Cost Effectiveness
- Trial name
- PAC ICare (NCT07635589)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Melanie Keats
Chronic Disease Prevention
Engaging Partners in Caring Communities
The goal of the EPICC observational study is to learn about capacity to implement evidence-based health promotion programs (EBPs) in congregations that are offered semi-structured technical assistance (TA).
- Trial name
- EPICC (NCT06932549)
- Testing
- Technical assistance is designed to integrate Expert Recommendations for Implementing Change (ERIC) strategies, and Getting To Outcomes-TA.
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tennessee State University
Health Knowledge, Attitudes, Practices
The Science Tooth Fairy: A Randomized Trial of a Storytelling-Based Educational Intervention to Promote Primary Tooth Donation in a Pediatric Setting
Study Overview Primary ("baby") teeth are unique biological samples because they can permanently store information about a child's early life health and development.
- Trial name
- STF RCT (NCT07711301)
- Testing
- Science Tooth Fairy Narrative, Cavities vs. Toothpaste, book by Didi Dragon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV (Human Immunodeficiency Virus), Continuum of Care
Adaptation and Implementation of an Evidence-based Approach to Advance HIV Prevention and Care
Transgender women in the intervention condition will attend TransAction individual risk reduction sessions; skill building and open group support sessions, and social events between baseline and 3-month assessment.
- Conditions
- HIV (Human Immunodeficiency Virus), Continuum of Care, Stigma
- Trial name
- NCT07495059
- Testing
- TransAction
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Chronic Obstructive Pulmonary Disease
Developing an Intervention to Optimize Virtual Care Adoption for COPD Management
VA is a leader in virtual care (VC), including the patient portal, mobile apps, and telehealth programs. VC has great utility for managing chronic conditions like chronic obstructive pulmonary disease (COPD).
- Trial name
- VC-OPTIONS (NCT05986214)
- Testing
- VC-OPTIONS
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Obesity, Diabetes
Lifestyle Changes Through Exercise and Nutrition
The goal of The LEAN project intervention is to promote weight loss, healthy dietary habits, increased physical activity, improved blood glucose and cholesterol, and weight related quality of life in obese African American adults…
- Trial name
- LEAN (NCT02863887)
- Testing
- Weight loss intervention
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Pennington Biomedical Research Center
Healthy Children
Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress
The goal of this randomized controlled trial is to learn if an outdoor science education intervention can improve primary school students' learning and well-being when compared to an indoor classroom-based science education…
- Trial name
- Bio-Explo (NCT07147634)
- Testing
- Outdoor science education, Indoor classroom-based science education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Chronic Low-back Pain (cLBP)
Pain Phenotypes in Individuals With Chronic Low Back Pain
This observational cross-sectional study aims to determine pain phenotypes in individuals with chronic low back pain (CLBP). Participants will be classified according to a mechanism-based clinical pain phenotyping algorithm as…
- Trial name
- NCT07766200
- Testing
- Pain classification method
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Elderly Patients
DOuble tasK Test On ergometeR - Basic Research on Acceptability and Use
The goal of the study is to show the concordance between the dual-task test achieved usually on an electronic treadmill and the dual-task test achieved with a cyclo-ergometer.
- Trial name
- DOKTORBRAU (NCT03800771)
- Testing
- Cycléo BRAU, GAITRITE®
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Trauma, Sexual
PHF Problematic Sexual Behavior of Youth Family Engagement
Efficacious child mental health services are only helpful if families engage in services; however, as many as 75% of families in need never establish contact with a mental health professional and greater than half of families…
- Trial name
- NCT04902287
- Testing
- Training Intervention for the Engagement of Families (TIES)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Educational Problems
Effectiveness of Haptic Technology in Teaching Urinary Catheterization Skill
Background: Haptic systems represent the highest level of computer based education technologies and enable students to learn at the highest level.
- Trial name
- NCT04653233
- Testing
- 3D Systems Touch Haptic Simulator
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Assessment, Self, Simulation-Based Education
Brief Title: Portable 3D Visual Material-Supported Simulation Training for Cervical Dilation Assessment
This randomized controlled trial aimed to evaluate the effectiveness of simulation-based education supported by a portable and mobile three-dimensional (3D) visual material on university students' knowledge of cervical dilation…
- Trial name
- NCT07705503
- Testing
- Portable 3D Visual Material-Supported Simulation Training, Standard Education
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Marmara University