Clinical trials: Basic Science, active
Basic Science
Evaluation of the Bioequivalence of RAY1225 Injection in Healthy Participants
This is a single-center, randomized, open, parallel-designed bioequivalence study aimed at evaluating the pharmacokinetic differences of RAY1225 injection after site and batch changes compared to before the changes.
- Trial name
- NCT07827027
- Testing
- RAY1225
- Volunteers
- 68 people
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Basic Science
LSD Occupancy of the Serotonin 2A Receptor in the Human Brain
The investigators wish to quantify the relation between administered dose of lysergic acid diethylamide (LSD), plasma LSD levels, and occupancy at the serotonin 2A receptor (5-HT2AR) using [11C]CIMBI-36 positron emission…
- Trial name
- dOccLS (NCT05953038)
- Testing
- Lysergic Acid Diethylamide Tartrate
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Healthy Volunteers, no Condition, Basic Science
Transcranial Ultrasonic Neuromodulation of Primary Visual Cortex and Primary Auditory Cortex in Humans
There are a number of disorders of the brain that have limited treatment options, such as chronic pain, addiction, and major depression.
- Trial name
- NCT07508722
- Testing
- Transcranial Focused Ultrasound Stimulation, Electroencephalography, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location
Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Task Demands and Spatial Attention (Expt 2.2)
How does one know what to look at in a scene? Imagine a "Where's Waldo" game - it's challenging to find Waldo because there are many 'salient' locations in the picture, each vying for one's attention.
- Trial name
- NCT07572630
- Testing
- Stimulus properties: task-defining feature
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Basic Science
Neural Basis of Sensory Learning: Brain Regions
The purpose of this study is to understand how the sensory and motor areas of the brain work together to keep a person's hand movements accurate (sensorimotor learning).
- Trial name
- NCT05079516
- Testing
- Theta burst transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Basic Science: Visual Attention in Healthy Participants, Attention
Probing the Role of Feature Dimension Maps in Visual Cognition: Manipulations of Relevant Locations on Salience Processing? (Expt 3.1 Pilot)
How do we know what's important to look at in the environment? Sometimes, we need to look at objects because they are 'salient' (for example, bright flashing lights of a police car, or the stripes of a venomous animal), while…
- Trial name
- NCT06852521
- Testing
- Stimulus Properties: Target Location, Stimulus Properties: Distractor Presence, Stimulus properties: Cue Validity
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Basic Science
A Mass Balance Study Of 14C-RAY1225 Injection In Healthy Chinese Participants
This is an open-label, single-center, single-dose study.
- Trial name
- NCT07460284
- Testing
- 14C-RAY1225
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Basic Science
The Neurobiological Effect of 5-HT2AR Modulation
The investigators wish to investigate neurobiological effects of serotonin 2A receptor modulation in healthy volunteers, contrasting effects of an agonist (psilocybin) and an antagonist (ketanserin).
- Trial name
- NeuroPharm2 (NCT03289949)
- Testing
- Psilocybine, Ketanserin
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gitte Moos Knudsen