Clinical trials: Behavior, Addictive, open to volunteers
Opioid-use Disorder, Chronic Pain
Optimization of NIBS for Treatment of Addiction
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic…
- Trial name
- NCT04379115
- Testing
- Active Comparator: Active tDCS + Active TUS
- Where
- 3 sites in United States
- Volunteers
- 126 people
- Sponsor
- Case Western Reserve University
Obesity & Overweight, Cardiometabolic Health Indicators
Tirzepatide Impact Assessment Study
This study examines how two different weight-loss strategies affect heart and metabolic health, as well as changes at the molecular level in the body.
- Conditions
- Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders
- Trial name
- TIA (NCT07740291)
- Testing
- GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Food Addiction Tendency, Obesity
Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
The goal of this clinical trial is to investigate how semaglutide affects the way the brain responds to food in adults with obesity and food addiction tendencies.
- Conditions
- Food Addiction Tendency, Obesity, Overweight
- Trial name
- NCT07732426
- Testing
- Semaglutide
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Cannabis Use Disorder
Trial of Tirzepatide for the Treatment of Cannabis Use Disorder
The purpose of this randomized, double-blind, placebo-controlled, multi-site clinical trial is to evaluate the safety and efficacy of tirzepatide in a sample of 100 patients diagnosed with moderate or severe CUD by DSM-5 criteria.
- Trial name
- NCT07468552
- Testing
- Tirzepatide
- Volunteers
- 100 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Homelessness, Substance Use Disorder (SUD)
Coordinated Access for Addiction Recovery and Equity in VA Supportive Housing
The Department of Housing and Urban Development-VA Supportive Housing (HUD-VASH) Program provides subsidized permanent housing with case management to homeless-experienced Veterans (HEVs).
- Trial name
- CARE-VASH (NCT07141394)
- Testing
- Medication for Addiction Treatment (MAT), Cognitive Behavioral Therapy for Substance Use Disorders (CBT-SUD)
- Where
- United States
- Volunteers
- 7,908 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Smoking, Smoking Cessation
A Study Evaluating the Use of an Indoor Air Quality Monitor to Promote a Smoke-free Home
The purpose of this study is to evaluate how using an indoor air quality monitor can promote a smoke-free home for cancer patients who are enrolled in MSK's Tobacco Treatment Program.
- Conditions
- Smoking, Smoking Cessation, Smoking Reduction, Smoking Habit
- Trial name
- NCT06693700
- Testing
- Indoor Air Quality Monitor AirGradient ONE
- Where
- 8 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Addiction Nicotine
The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction
This clinical trial evaluates the VapeAway system, a novel, multi-modal intervention designed to address the multifaceted nature of vaping addiction.
- Trial name
- CONQUER (NCT07322432)
- Testing
- VapeAway filter system
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VapeAway
Opioid-Related Disorders, Drug Addiction
Outcome Inference in the Sensory Preconditioning Task in Opioid-Use Disorder
Background: People with addictions often find it hard to choose the long-term benefits of abstinence over the short-term effects of using drugs.
- Trial name
- NCT03745339
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Nicotine Dependence, Transcranial Magnetic Stimulation
Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)
The goal of this clinical trial is to learn if a combination of varenicline and enhanced accelerated Transcranial Magnetic Stimulation (aTMS) works to help adults quit using nicotine products.
- Conditions
- Nicotine Dependence, Transcranial Magnetic Stimulation, Vaping, Smoking Cessation
- Trial name
- V-TMS (NCT07145866)
- Testing
- Varenicline, Transcranial Magnetic Stimulation, Nicotine Cessation Counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Methamphetamine Use Disorder
Psilocybin for Methamphetamine Addiction
The primary purpose of this study is to preliminarily determine if the use of psilocybin to promote abstinence from methamphetamine is feasible and well tolerated in populations such as those found in Northern Louisiana.
- Trial name
- NCT06899594
- Testing
- Psilocybin 25 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kevin Murnane
HIV, Substance Use Disorder (SUD)
Combining Social Network Strategies and Routine Substance Use Screening
This study aims to improve health care for people who may have HIV or substance use disorders by bringing two services to a large community health center in Chicago.
- Trial name
- SNSUS (NCT07414459)
- Testing
- Substance use disorder screening, Social network intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Diego
Alcohol Use Disorder, Alcohol Use Disorder (AUD)
Optimizing Smart Technology for Addiction Recovery
The goal of this study is to develop a machine-learning guided recovery messaging system. The main question it aims to answer is can messages be used to: help people to improve their health make changes in people's lives to…
- Trial name
- STAR (NCT07573540)
- Testing
- STAR
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- University of Wisconsin, Madison
Problematic Use of Mobile Phones
Cognitive Behavioral Therapy for Mobile Phone Addiction in Hospitalized Patients
Problematic mobile phone use is excessive dependence and use of electronic products and their functions, which affects the daily life of users.
- Trial name
- CBT (NCT07457658)
- Testing
- Cognitive-behavioral therapy, Traditional treatment in the ward
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sir Run Run Shaw Hospital
Addictions
téléwork and Consumer Behavior: Longitudinal Study
Alcohol and nutritional factors are among the leading causes of preventable cancer. Knowing that so many health problems could be avoided thanks to behavioral changes, the identification of the factors at the origin of these…
- Trial name
- SUBSTANCES_1 (NCT07788352)
- Testing
- data collection
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Opioid Use Disorder, Chronic Pain
Digital Treatment for Chronic Pain and Addiction in Veterans With Opioid Use Disorder Receiving Buprenorphine
Chronic pain is common in individuals with opioid use disorder (OUD) and the first-line treatment, Medication for OUD (MOUD), does not address the considerable functional impairments associated with chronic pain.
- Trial name
- NCT07361432
- Testing
- Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT), Enhanced Treatment as Usual (ETAU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Substance Use Disorders, Hiv
HIV, Equity, and Addiction Training (HEAT) Program
This project is a pilot study to determine the feasibility and acceptability of a telemedicine intervention for substance use disorder service delivery in diverse people living with HIV in Alabama.
- Conditions
- Substance Use Disorders, Hiv, Opioid Use Disorder, Stimulant Use (Diagnosis)
- Trial name
- HEAT (NCT06370481)
- Testing
- Telemedicine, Standard of care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Opioid-use Disorder
Smartphones for Opiate Addiction Recovery
Treatments for opioid addiction exist, but effectiveness is compromised when subjects use illicit opiates during treatment. Reuse rates during treatment can be high, and reducing illicit opiate use during treatment has thus…
- Trial name
- SOAR (NCT05033028)
- Testing
- Smartphone app
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- NYU Langone Health
Depression, Alcohol Use Disorder
Ketamine for Combined Depression and Alcohol Use Disorder
The goal of this clinical trial is to investigate the effects of ketamine, in combination with standard inpatient addiction therapy, for adults with depression and alcohol use disorder.
- Trial name
- KeDA (NCT06090422)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- University Hospital of North Norway
Smartphone Addiction, Neck Pain
Smartphone Addiction and Cervical Muscular Health
This cross-sectional observational study investigates how smartphone addiction affects neck pain severity, pressure pain threshold, and mechanical properties of cervical muscles in healthy young adults.
- Trial name
- NCT07038980
- Testing
- Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Saglik Bilimleri Universitesi
Addiction Disorders, Addictive Behaviors
Understanding the Long-term Paths of People With Addictions
The study is an open prospective cohort study. Participants are assessed at the start of their care in an addiction treatment unit using the Addiction Severity Index (ASI) and the Mini International Neuropsychiatric Interview…
- Conditions
- Addiction Disorders, Addictive Behaviors, Addiction
- Trial name
- ADDICT AQUI (NCT07249970)
- Testing
- Addiction Severity Index
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux