Clinical trials: Behavior, Addictive, open to volunteers
Nicotine Addiction, Craving
Advancing VR-based Attentional Bias as a Biomarker for Tobacco Use Disorder
The proposed project will include enrollment of 200 daily tobacco cigarette users, ages 22+, from the San Diego community. Participants will be assessed on the VR Nicotine Cue Exposure paradigm then randomized (stratified on age…
- Trial name
- VR (NCT06582888)
- Testing
- Varenicline Tartrate
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Diego
Chronic Pain, Opioid Use Disorder
Combined THC and CBD for OUD and Chronic Pain
The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid…
- Trial name
- NCT06544291
- Testing
- CBD 300mg, CBD 600mg
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Yale University
Addiction
Trajectories and Reactions of Users and Relatives Consulting French Youth Addiction Services
In France, the "Consultations Jeunes Consommateurs" (CJC) are the services specialized in the reception of young people for addiction problems. There are more than 500 CJCs throughout France.
- Trial name
- TRYAD (NCT05609474)
- Where
- France
- Volunteers
- 1,430 people
- Sponsor
- Hôpital le Vinatier
Community Health Services, Respiratory Disease
INSPIRE Respiratory Health Program in Botucatu, São Paulo, Brazil
The goal of this observational study is to evaluate the implementation of the INSPIRE program and to plan actions for the preparation, coordination, monitoring, diagnosis, and treatment of respiratory diseases in the municipality…
- Conditions
- Community Health Services, Respiratory Disease, Tobacco Smoking
- Trial name
- NCT06673225
- Testing
- Analysis of results
- Where
- Brazil
- Volunteers
- 2,000 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Smartphone Addiction, Thumb Injury
Smartphone Addiction on the Biomechanical Properties of Thumb Muscles and Thumb Sensory Sensitivity
This study will aim to assess the effects of smartphone addiction on thumb muscle biomechanics and sensory sensitivity among university students.
- Trial name
- NCT07040267
- Testing
- Thumb evaluations
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Saglik Bilimleri Universitesi
Elbow Joint Performance, Ms Strength, Proprioception and Elbow Functional Abilities
SMART PHONE ADDICTION AND ELBOW JOINT PERFORMANCE
smart phone addiction negatively impacted the pain in the muscles of the neck, shoulder, elbow, and the hand. the negative impact of prolonged smartphone use has shown an association between smartphone addiction and…
- Trial name
- NCT06530446
- Testing
- one group. observational study
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alcohol Use Disorder
Peer Support in Alcohol Dependence
Alcohol use disorder (AUD) affects between 4% and 6% of French adults, and requires appropriate medical treatment. However, 20-40% of patients with AUD are lost to follow-up at an early stage.
- Trial name
- PEERSIAD (NCT06381609)
- Testing
- Quality life questionnaire AQoLS, Quality life questionnaire Euroqol EQ-5D-5L, Peer support consultations
- Where
- 5 sites in France
- Volunteers
- 626 people
- Sponsor
- Hospices Civils de Lyon
Cannabis Use Disorder
Lemborexant for Cannabis Use Disorder
The goal of this clinical trial is to investigate the use of Lemborexant as a treatment for moderate to severe Cannabis Use Disorder (CUD). The main questions it aims to answer are: 1.
- Trial name
- LemboCAN (NCT07802990)
- Testing
- Lemborexant 10mg, Brief Behavioural Intervention
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of Calgary
Addiction, Addiction Disorders
Evaluation of the ADD'Pro Vocational Reintegration Program (ADD-PRO-EVAL)
The goal of this clinical trial is to evaluate whether an integrated medico-psychosocial vocational support program (ADD'Pro) can improve employment outcomes in adults with substance use disorders receiving care at a specialized…
- Conditions
- Addiction, Addiction Disorders, Substance Use Recovery, Return to Work
- Trial name
- ADD-PRO-EVAL (NCT07520617)
- Testing
- ADD'Pro Program, Standard Care (in control arm)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Addiction
Role of Craving in the Transition Across Level of Addiction Severity: A Longitudinal Study.
Substance/Alcohol Use disorders are defined as a loss of control over the use despite harmul consequences, as well as an intense and persistent urge to use, also called craving.
- Trial name
- CARDEMA (NCT07734363)
- Testing
- Observational assessments (EMA and annual DSM-5 evaluations)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University of Bordeaux
Nicotine Use Disorder, Substance Use Disorders
Temporal Interference Methods for Addiction Treatment
This clinical study is testing whether a new non-invasive brain stimulation method, called temporal interference (TI), can reduce nicotine cravings and usage in people who vape.
- Trial name
- NCT07210268
- Testing
- TI-NDBS
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Indiana University
Alcohol Use Disorder (AUD)
Social Identity Mapping for Adolescent Recovery
The goal of this clinical trial is to address the gap between clinical treatment and adolescents' lived social environments by developing and testing a novel, interactive intervention-SIM-AiR-that directly targets social risk and…
- Trial name
- SIMAiR (NCT07474207)
- Testing
- SIM-AiR
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Depression, Addiction
Adaptation and Pilot Testing of Web and Mobile Interface for the ATTACH™ Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stressors (depression, addiction, family violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of infection.
- Conditions
- Depression, Addiction, Domestic Violence, Poverty
- Trial name
- ATTACH™ (NCT04857775)
- Testing
- Attachment and Child Health (ATTACH) Parenting Program
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Food Addiction Tendency, Obesity
Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
The goal of this clinical trial is to investigate how semaglutide affects the way the brain responds to food in adults with obesity and food addiction tendencies.
- Conditions
- Food Addiction Tendency, Obesity, Overweight
- Trial name
- NCT07732426
- Testing
- Semaglutide
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Mental Health Issue
The Relationship Between Internet-use Behavior and Mental Health in Youth
Introduction: WHO defines youth as 15-24 years age group. At this stage, the brain is still under development, with high impulsiveness, being fond of stimulation and yearning for peer life.
- Trial name
- NCT06284551
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Opioid Dependence, Opioid Use Disorder (OUD)
VK4-116 Phase I Study With Food-Effect
This first-in-human, randomized, double-blind, placebo-controlled, single ascending dose (SAD), phase I study is designed to assess the safety, tolerability and pharmacokinetics of VK4-116 in healthy volunteers in fasted and fed…
- Trial name
- NCT06808932
- Testing
- VK4-116
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Trauma and Stress-related Disorders, Substance Use Disorder (SUD)
Protocol Study on Addiction, Trauma and Immigration Among Vulnerable Young Adults in Grand Est
The ATICC study (Addiction, Trauma, and Immigration, Prevention and Cross-Cultural Support for Care) investigates the complex relationships between trauma, substance use, migration experiences, and mental health perceptions among…
- Conditions
- Trauma and Stress-related Disorders, Substance Use Disorder (SUD), Substance Use Risk
- Trial name
- ATICC (NCT06922721)
- Testing
- Focus group
- Where
- 7 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Lorraine
De Quervain Tenosynovitis, Smartphone Addiction
De Quervain Syndrome Among Medical Students with Smart Phone Addiction
To investigate the prevelance of the de quervain tenosynovitis among the Egyptian medical students with smartphone addiction
- Trial name
- NCT06731634
- Testing
- Hand grip strength dynamometer, pinch strength dynamometer, Finkelstein test
- Volunteers
- 103 people
- Sponsor
- Cairo University
Mental Health Issue, Substance Use Disorders
Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & Addictions Service to Usual Case Management on Dropout Rates in a Vocational Training Program
Youth unemployment is a chronic problem in most societies. Some young adults are neither in employment, education or training (NEET), and are at high risk of chronic unemployment, social disengagement and poor quality of life.
- Conditions
- Mental Health Issue, Substance Use Disorders, Distress, Emotional
- Trial name
- TeachMeToBuild (NCT05626374)
- Testing
- Basic Case Management, Basic Case Management plus Distress Tool, Basic Case Management plus rapid mental health & addictions healthcare access
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Royal Victoria Hospital, Canada
Addiction, Substance Use Disorder (SUD)
HABITS Study (Helping Addiction by Individualized Therapeutic Stimulation): Pilot Trial of Deep Brain Stimulation Guided By Stereoelectroencephalography for Treatment-Refractory Substance Use Disorders
Substance use disorder (SUD) or addiction to drugs/alcohol is a devastating disease. Over 40,000 overdose deaths have happened in Canada since 2016, 1 in 5 Canadians will have a SUD, and 70% of those with SUD continue to relapse…
- Trial name
- HABITS (NCT06973512)
- Testing
- deep brain stimulation and stereoelectroencephalography
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre for Addiction and Mental Health