Clinical trials: Behavior, Sex
Congenital Adrenal Hyperplasia
Effects and Importance of Epinephrine/Adrenalin Deficiency in CAH
Individuals with CAH produce lower levels of epinephrine (adrenalin) than controls. This can be correlated to the CYP21A2 genotype and is most pronounced in the classic forms.
- Trial name
- NCT05162950
- Testing
- physical exercise as a standardized high intensity exercise test, Stress vulnerability
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
HIV, Depression
An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)
HIV continues to spread among Black men who have sex with men (MSM), but few interventions target high-risk Black men who have sex with men and women (MSMW).
- Conditions
- HIV, Depression, Posttraumatic Stress Disorder
- Trial name
- ES-HIM (NCT01641146)
- Testing
- Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm
- Where
- 4 sites in United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Angelman Syndrome, Smith-Magenis Syndrome
Ghrelin in Patients With a Rare Disease Associated With Intellectual Disability, and Hyperphagia, and/or Overweight, and/or Obesity
A significantly higher proportion of patients with rare diseases (RD) with intellectual disability (ID), present hyperphagia, overweight or obesity, compared to the general population.
- Conditions
- Angelman Syndrome, Smith-Magenis Syndrome, X Fragile Syndrome, Epilepsy
- Trial name
- HOGRID (NCT04768803)
- Testing
- acylated and unacylated ghrelin dosages
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Toulouse
Gender Dysphoria
Cross-sex Hormone Therapy and Neuronal Plasticity
Transgender women (male-to-female) were invited to participate in this study to test the impact of Cross-Sex Hormone Therapy (CSHT) in the brain.
- Trial name
- NCT03651427
- Testing
- Estradiol
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mental Health Issue, Parent-Child Relations
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
The purpose of this study is to assess the efficacy of an LGBTQ-affirmative individual cognitive behavioral psychotherapy (CBT) and LGBTQ-affirmative family therapy (attachment-based family therapy for sexual and gender minority…
- Trial name
- NCT05766592
- Testing
- LGBTQ-affirmative CBT, ABFT-SGM
- Where
- 2 sites in United States, Israel
- Volunteers
- 124 people
- Sponsor
- Yale University
Breast Cancer, Cancer Survivor
Quality of Life in Female Breast Cancer Survivors and Their Spouse, Partner, or Acquaintance
RATIONALE: Studying quality of life in breast cancer survivors may help determine the long-term effects of breast cancer and may help improve the quality of life for future breast cancer survivors.
- Conditions
- Breast Cancer, Cancer Survivor, Cognitive/Functional Effects, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00309933
- Testing
- cognitive assessment, psychosocial assessment and care, quality-of-life assessment
- Where
- 104 sites in United States
- Volunteers
- 2,697 people
- Sponsor
- Eastern Cooperative Oncology Group
Knowledge, Behavior
Socialization To Enrich Participation & Support Sexuality for Young People With I/DD
The goal of this clinical trial is to test the effectiveness of a 6-week socialization and sex education curriculum (STEPS2) in young people (aged 16-27 years) with intellectual and developmental disabilities (I/DD), including…
- Trial name
- STEPS2 (NCT06231485)
- Testing
- STEPS2, STYH
- Where
- United States
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Hiv
Knowledge Attitudes Behaviours and Practices Regarding HIV of Men Who Have Sex With Men in the French Antilles and French Guiana
determine the Knowledge attitudes behaviours and practices regarding HIV of men who have sex with men in the French Antilles and French Guiana
- Trial name
- NCT03359720
- Testing
- no intervention survey
- Volunteers
- 766 people
- Sponsor
- Centre Hospitalier de Cayenne
Urinary Incontinence,Stress
Correlation Between Changes in Sex Hormone Levels and Stress Urinary Incontinence in Women
The goal of this observational study is to learn about the relationship between stress urinary incontinence and endogenous steroids in women, especially its occurrence and severity with androgens and estrogens.
- Trial name
- NCT06109623
- Testing
- observation, sex hormone
- Volunteers
- 1,226 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Erectile Dysfunction, Smoking
A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers
Smokers are at higher risk of developing Erectile dysfunction (ED) independent of age and comorbidities. Sildenafil is a cytochrome p3A4 (CYP3A4) substrate used for enhancing the erectile function in males.
- Conditions
- Erectile Dysfunction, Smoking, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT04100759
- Testing
- Sildenafil 50 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Medication Adherence
Nurse Delivered Cell Phone Adherence Intervention (Pick It UP)
Persistent adherence to antiretroviral therapy is necessary for the successful treatment of HIV infection. The proposed research will test a theory-based behavioral intervention that includes objectively monitoring HIV treatment…
- Trial name
- PIU (NCT01359280)
- Testing
- Adherence Counseling, General Health Counseling, Text Messages
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Connecticut
Substance Use, Sexual Risk Behaviors
Targeting HIV Risk Behaviors in Juvenile Drug Court-Involved Youth
This study is designed to gain knowledge about effective interventions for reducing HIV risk in a high risk population. A new Risk Reduction Therapy for Adolescents (RRTA) will be compared to usual services received by youth in…
- Trial name
- NCT01511380
- Testing
- Risk Reduction Therapy for Adolescents, Usual services
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Human Papillomavirus Vaccination, Cervical Cancer Prevention
Integrating HPV Education Into School Health Programs in Cambodia and Kenya
The Clinton Health Access Initiative conducted a mixed-methods, school-based interventional study in Cambodia and Kenya to evaluate whether integrating age-appropriate human papillomavirus (HPV) education into existing school…
- Trial name
- NCT07784283
- Testing
- Integrated HPV Education
- Where
- 5 sites in Cambodia, Kenya
- Volunteers
- 9,054 people, healthy volunteers welcome
- Sponsor
- Clinton Health Access Initiative Inc.
Syndromic and Metabolic Cardiomyopathy, Cardiomyopathies
SMCs With LVH Compared to HCM
The goal of this cohort study is to investigate the clinical characteristics of SMCs and to explore the difference in cardiovascular outcomes in comparison to age-, sex-, and admission year-matched HCM patients.
- Trial name
- NCT07006974
- Testing
- SMCs
- Where
- China
- Volunteers
- 165 people
- Sponsor
- China National Center for Cardiovascular Diseases
Fragile X Syndrome
Trial of Sertraline to Treat Children With Fragile X Syndrome
This study is a control trial of sertraline (Zoloft) in fragile X syndrome children aged 2 years to 5 years 8 months old. The trial is six months long, and each participant will receive a series of tests at both the beginning and…
- Trial name
- NCT01474746
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Randi J. Hagerman, MD
Post-traumatic Stress Symptoms, Psychosocial Distress
An RCT of Trauma Focused-Cognitive Behavioral Therapy With Sexually Exploited, War-affected Girls in the DRC
To date, no RCT has examined the efficacy of Trauma-Focused Cognitive Behavioral Therapy with Sexually Exploited, War Affected Adolescent Girls in the Democratic Republic of Congo.
- Trial name
- NCT01483261
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Republic of the Congo
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Hiv, Mental Health Issue
Striving Towards EmPowerment and Medication Adherence R01
This is a study for Black women living with HIV to test a counseling program for Black women living with HIV. This participant may be a good fit if the participant is a Black woman, living with HIV, has a history of trauma, and…
- Trial name
- NCT06463886
- Testing
- STEP-AD, Enhanced treatment as usual (E-TAU)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Miami
Gender-based Violence, Adherence
Impacts of Clean Cookstoves and Empowerment Training on Women's Health in Refugee Settings
The main objective of this study is to understand the links and outcomes of adoption of a cleaner cookstove/fuel and exposure to a personal empowerment training on women's health outcomes in a Congolese refugee camp in Rwanda…
- Conditions
- Gender-based Violence, Adherence, Mental Health Wellness 1, Empowerment
- Trial name
- NCT04081441
- Testing
- Inyenyeri clean cookstove and fuel system, I-ACT (Individual, Agency-Centered Training) workshop
- Where
- Rwanda
- Volunteers
- 1,555 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV Infections
A Study of Ritonavir/Indinavir Combination in HIV-Infected Patients
The purpose of this study is to determine how many HIV-infected patients continue taking ritonavir/indinavir combination after having taken indinavir three times a day as part of their anti-HIV drug therapy.
- Trial name
- NCT00002223
- Testing
- Indinavir sulfate, Ritonavir
- Where
- 6 sites in United States
- Sponsor
- Abbott
HIV Infections
A "Pre-Enrollment" Protocol for HIV-Infected Adolescents
PRIMARY: To identify, characterize, and co-enroll HIV-infected adolescents into existing and future ACTG (or other NIH-sponsored) HIV treatment protocols through the systematic and recurrent assessment of eligibility.
- Trial name
- NCT00000780
- Where
- 51 sites in United States, Puerto Rico
- Volunteers
- 250 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)