Clinical trials: Behavior Problems, open to volunteers
Sleep, Psychological Distress
The Development and Evaluation of Sleep Intervention for Perinatal Family
Background: Sleep disruptions and disturbances are highly prevalent among new mothers and fathers and negatively affect their mental health and infant development outcomes.
- Conditions
- Sleep, Psychological Distress, Perinatal Problems
- Trial name
- NCT06487650
- Testing
- sleep intervention, Control group
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Behavior Problem of Childhood and Adolescence, Parent Management Training
Behavioral Parent Training With and Without AI Support for Children With Disruptive Behaviors
The goal of this clinical trial is to learn if adding an artificial intelligence (AI) application called to standard Behavioral Parent Training (BPT) helps families with children who have disruptive behavior problems.
- Conditions
- Behavior Problem of Childhood and Adolescence, Parent Management Training, Artificial Intelligence (AI), Disruptive Behaviours
- Trial name
- NCT07469215
- Testing
- Behavioral Parent Training (BPT), Behavioral Parent Training (BPT) + Support of AI app
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundació Sant Joan de Déu
Anesthesia, Behavior Change
pEEG-Guided Anesthesia and Behavioral Outcomes in Children
Post-hospitalization behavioral changes are common in children after surgery and general anesthesia and may persist for varying durations depending on individual and perioperative factors.
- Conditions
- Anesthesia, Behavior Change, Behavior Child Problems, Anesthesia Depth Monitoring
- Trial name
- NCT07473024
- Testing
- Processed EEG Monitoring, Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Istanbul University
Opioid Use Disorder, Alcohol Use Disorder
Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis
The opioid epidemic has become one of America's deadliest crises, surpassing car crashes, firearms, and HIV/AIDS as a leading cause of death for Americans under fifty years of age.
- Conditions
- Opioid Use Disorder, Alcohol Use Disorder, Health Risk Behaviors, Criminal Behavior
- Trial name
- RB (NCT05665179)
- Testing
- Removing Barriers to Recovery
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- University of Michigan
ADHD, Sleep Problems
A Clinical Trial of Iron Supplementation for Youth With ADHD and Restless Sleep
The goal of this clinical trial is to learn if iron supplementation works to restless sleep in youth with ADHD. A second goal is to learn if iron supplementation helps to ease ADHD symptoms.
- Trial name
- NCT07061470
- Testing
- Ferrous Sulfate
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Schizophrenia, Autism-Related Irritability
A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents
The purpose of this study is to evaluate the long-term safety and tolerability of Xanomeline and Trospium Chloride for the treatment of psychiatric disorders in children and adolescents
- Trial name
- NCT07424404
- Testing
- KarXT, KarX-EC
- Where
- 104 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Sleep Problems, Psychological
WhatsApp-based Psycho-socio-educational Intervention (WeLove) for Prevention of Psychological and Sleep Problems in Pregnant Women and Their Partners: A Three-arm Double-blinded Pilot Randomised Controlled Trial
Objectives: (1) evaluate the feasibility and acceptability of the WhatsApp-based psycho-socio-educational intervention (WeLove); (2) preliminarily examine the effects of the intervention on psychological symptoms (depression…
- Conditions
- Sleep Problems, Psychological, Well-Being, Psychological
- Trial name
- WhatsApp-based (NCT06768190)
- Testing
- WhatsApp as usual, WhatsApp-based psycho-socio-educational intervention (WeLove)
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Body Dysmorhpic Disorder
Psychiatric Disorders in Dermatiological Diseases
The aim of this study: 1. Evaluate the presence of body dysmorphic disorder in children with dermatological diseases compared to healthy controls. 2.
- Trial name
- NCT07521813
- Testing
- Questionnaire and Physical Exam
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sohag University
Depression / Major Depressive Disorder, Conduct Disorders in Children
Optimizing Treatment for Depressed Parents of Children With Emotional and Behavioural Problems
Standard Behavioral Parent Training (BPT) is often less effective for parents experiencing depression. As such, the Addressing Depression and Positive Parenting Techniques (ADAPT) intervention is a novel BPT tailored to address…
- Conditions
- Depression / Major Depressive Disorder, Conduct Disorders in Children, Disruptive Behaviour in Children, Parenting Intervention
- Trial name
- OPTED (NCT07749521)
- Testing
- ADAPT Treatment, Incredible Years Parenting Program (IYPP)
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of Toronto
Problem Behavior, Aggression
Extensions of Resurgence as Choice
Although behavioral treatments for decreasing destructive behavior, such as differential reinforcement of alternative behavior (DRA), are effective in the clinic, problem behavior often returns when a caregiver does not give the…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05537610
- Testing
- CDT, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Schizophrenia, Treatment Resistant Depression (TRD)
Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment
The disruption of immune system is a key candidate in the pathogenesis of psychiatric disorders, especially those resistant to traditional treatments.
- Conditions
- Schizophrenia, Treatment Resistant Depression (TRD), Bipolar Disorder (BD), Catatonia
- Trial name
- BIO-INM (NCT07741981)
- Testing
- Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Centre Hospitalier St Anne
Addictive Behaviors, Emotion Regulation
A Novel Adaptation of the Unified Protocol (UP) as a Transdiagnostic Intervention for Emotional Disorders in Addictive Behaviors
This study aims to pilot a psychological intervention protocol designed for individuals who use substances and who experience difficulties in emotion regulation.
- Trial name
- UP-TIED-AB (NCT07738081)
- Testing
- Transdiagnostic cognitive-behavioral therapy, Treatment as usual
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Oviedo
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Suicide Risk, Psychiatric Disorders
Improving Mental Health Treatment for Individuals in Crisis Interacting With the Criminal-Legal System
The proposed Center will leverage burgeoning real-time data linkage capabilities among health systems, Medicaid payors, and criminal legal (e.g., jail booking data, jail release data) systems, to identify individuals coming in…
- Trial name
- NCT06564948
- Testing
- Treatment as usual (TAU), FSJS, FSJS+Navigator Intervention
- Where
- United States
- Volunteers
- 1,040 people
- Sponsor
- Cambridge Health Alliance
Chronic Pain, Physical Activity
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
The investigators aim to conduct a randomized controlled trial to compare two symptom-management programs for Black older adults with early cognitive decline (self-reported confirmed by testing) and chronic pain.
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Trial name
- HABIT (NCT06246929)
- Testing
- MBCT+w, ALED
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Delayed Sleep-Wake Phase Disorder, Sleep Disorder
Sleep in Psychiatric Care (SIP): Treatment for Comorbid Delayed Sleep-Wake Phase Disorder (DSWPD)
Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep…
- Conditions
- Delayed Sleep-Wake Phase Disorder, Sleep Disorder, Psychiatric Disorder
- Trial name
- SIP (NCT05177055)
- Testing
- Group-based light therapy at gradually advanced timing for DSWPD, Group-based light therapy at gradually advanced timing for DSWPD and additive bb-glasses, 6-week wait list for sleep-school
- Where
- 2 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital
Parkinson's Disease (PD), Essential Tremor
LIFUS For Neurological Disorders
Low intensity focused ultrasound (LIFUS) has the potential to be used as a means of non-invasive neuro-modulation. To this day, the use of LIFUS is under investigation.
- Conditions
- Parkinson's Disease (PD), Essential Tremor, Orthostatic Tremor, Dystonia
- Trial name
- NCT07417280
- Testing
- LIFUS
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Mental Disorder
Evaluation of the Efficacy of Immunomodulatory Therapy in Case of Psychiatric Disorders With Proven Dysimmunity.
This is an open phase III randomized clinical trial studying the superiority of management by immunomodulator treatment of psychiatric disorders (psychosis and bipolar disorders) for patients previously identified as carriers of…
- Trial name
- TIM-DePisT (NCT05946486)
- Testing
- immunomodulatory treatment by rituximab
- Where
- 9 sites in France
- Volunteers
- 174 people
- Sponsor
- University Hospital, Bordeaux
Sleep Disorder; Insomnia Type, Psychiatric Disorders
Sleep in Psychiatric Care (SIP): A Transdiagnostic Group-based Sleep-school as Treatment for Comorbid Insomnia
Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep…
- Trial name
- SIP (NCT04463498)
- Testing
- Group-based cognitive behavioral therapy for insomnia, Group-based cognitive behavioral therapy for insomnia and additive bb-glasses, 8-week wait list for sleep-school
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital