Clinical trials: Behavioral Activation
Down Syndrome
Promoting Health Through Parent Empowerment and the Activation of Routines (PrO-PEAR)
This study will examine the feasibility of the Promoting Health through Parent Empowerment and the Activation of Routines (Pro-PEAR) intervention using a open case-series for intervention optimization followed by a pilot RCT in…
- Trial name
- Pro-PEAR (NCT05020366)
- Testing
- Promoting Health through Parent Empowerment and the Activation of Routines, Enhanced Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Depression
Activating and Connecting Teens (ACT) Study
National data indicate over 650,000 children and adolescents are exposed to physical, sexual, or emotional abuse or physical or emotional neglect each year.
- Trial name
- ACT (NCT03438656)
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetes Mellitus, Depression
Behavioral Activation Therapy for Rural Veterans With Diabetes and Depression
This clinical trial will compare the effectiveness of the Healthy Outcomes through Patient Empowerment (HOPE) intervention to enhanced usual care (EUC) for diabetes and depression at 6 and 12 month follow-up.
- Trial name
- NCT01572389
- Testing
- Healthy Outcomes through Patient Empowerment (HOPE), Enhanced Usual Care
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
ADHD, Attention Deficit Hyperactivity Disorder
Neurobiological Basis of Response to Guanfacine Extended Release in Children and Adolescents With ADHD
This study proposes to evaluate the effects of guanfacine extended release on brain activation during fMRI in children and adolescents with ADHD between the ages 8-15 and ADHD subjects randomized to placebo treatment.
- Trial name
- NCT01709695
- Testing
- Guanfacine Hydrochloride XR
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Tobacco Dependence, PTSD
Behavioral Activation for Smoking Cessation in PTSD
The purpose of this study is to examine whether behavioral activation as an adjuvant to standard smoking cessation treatment improves smoking cessation outcomes among veterans with PTSD relative to a comparably intense…
- Trial name
- NCT01995123
- Testing
- Behavioral Activation Therapy, Health and Smoking Education, Standard Smoking Cessation Therapy
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Opioid Withdrawal
Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal
This Phase 1b/2 inpatient study assessed the safety, pharmacokinetics, and early signs of efficacy of escalating doses of BXCL501 versus placebo following discontinuation of morphine maintenance.
- Trial name
- NCT04470050
- Testing
- Dexmedetomidine
- Where
- 3 sites in United States
- Volunteers
- 225 people
- Sponsor
- BioXcel Therapeutics Inc
Posttraumatic Stress Disorder, Depression
Behavioral Activation for PTSD/Depression Treatment in OIF/OEF Veterans
The present study is a randomized, controlled trial that compares Behavioral Activation (BA) to Treatment As Usual (TAU) in PTSD Specialty clinics, as early psychotherapeutic interventions for OIF/OEF veterans with posttraumatic…
- Trial name
- NCT00805532
- Testing
- Behavioral Activation treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease
Home-base Kidney Care in Zuni Indians
People reach End Stage Renal Disease (ESRD) due to progressive chronic kidney disease (CKD). CKD is associated with increased risks for heart disease and death.
- Trial name
- HBKC (NCT02915029)
- Testing
- Educational and lifestyle coaching
- Volunteers
- 125 people
- Sponsor
- University of New Mexico
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Prolonged Grief Disorder
Treatment of Prolonged Grief Disorder in Combat Veterans
The purpose of this study is to compare the efficacy of an experimental treatment (termed BATE-G) for Prolonged Grief Disorder (PGD) in Veterans compared to the current, VA-approved standard of care treatment.
- Trial name
- PGD (NCT02283333)
- Testing
- BATE-G, Standard Treatment
- Where
- 2 sites in United States
- Volunteers
- 155 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Invasive Breast Carcinoma
Adaptive Training Exercise Programs for Improving Cardiorespiratory Fitness After Breast Cancer Treatment, The ACTIVATE Trial
This clinical trial studies the feasibility of implementing various adaptive training exercise programs to improve cardiorespiratory fitness in patients after receiving breast cancer treatment.
- Trial name
- ACTIVATE (NCT04667481)
- Testing
- Aerobic Exercise Intervention, Resistance Exercise Intervention, Exercise Intervention: Digital copies and outline of sessions
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Washington
Smoking Cessation, Acute Coronary Syndrome
Post Acute Coronary Event Smoking Study
Smoking and depressed mood are both predictive of mortality following Acute Coronary Syndrome. However, to date, no counseling treatment has been designed to target smoking cessation and manage mood in this population.
- Trial name
- PACES (NCT01964898)
- Testing
- Behavioral Activation (BA), Standard Smoking Cessation Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Miriam Hospital
Depressive Symptoms, Inflammation
Reducing CVD Risk in Caregivers: A Brief Behavioral Activation Intervention
Cardiovascular disease and depression are some of the most costly illnesses to society, and caring for a loved-one with Alzheimer's disease has been associated with increased risk for both depression and cardiovascular disease.
- Trial name
- NCT01802554
- Testing
- Pleasant Events Program (PEP), Information Support (IS)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Depression
A CBT-based Mobile Intervention as First Line Treatment for Adolescent Depression During COVID-19
Over 3 million teenagers in the USA have depression, and rates of depression and suicide are sharply increasing. Teenage depression has far-reaching consequences including impairments in academic and work performance and social…
- Trial name
- NCT04524598
- Testing
- Limbix Spark, Psychoeducation
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Limbix Health, Inc.
Diabetes Mellitus, Type 2
Evaluation of a Patient Portal Intervention for Diabetes: A Pilot Randomized Controlled Trial
The purpose of this study is to conduct a two-arm, parallel-design, pragmatic randomized controlled trial of a patient portal intervention for diabetes, My Diabetes Care, to evaluate its effect on patient activation and secondary…
- Trial name
- NCT03947333
- Testing
- My Diabetes Care
- Where
- United States
- Volunteers
- 287 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Pain
Back on Track to Healthy Living Study
Chronic pain is a significant problem affecting millions of Americans. Research has shown that psychological treatments can help people with chronic pain manage their pain and improve their quality of life.
- Trial name
- BOT (NCT03687762)
- Testing
- Cognitive Therapy (CT), Mindfulness Meditation (MM), Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 397 people
- Sponsor
- University of Washington
Stress (Psychology)
Mobile Self-Management Program for Stress Reduction in Young Adults
The goal of this clinical trial is to learn if a mobile self-management program that combines Positive Psychology (PP) and Behavioral Activation (BA) helps reduce stress in young adults in South Korea.
- Trial name
- NCT07174544
- Testing
- Mobile Self-Management Program integrated with Positive Psychology and Behavioral Activation
- Where
- South Korea
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Schizophrenia, Schizoaffective Disorder
Get Moving and Get Well - Pilot Study
Individuals with serious mental illness have greater morbidity from physical illness and mortality than the general population, but tend not to initiate or sustain engagement in health promotion interventions.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
- Trial name
- GMGWP (NCT01884025)
- Testing
- Get Moving and Get Well, Health and Humor Class
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Leukemia
Efficacy and Safety of Midostaurin in Patients With Aggressive Systemic Mastocytosis or Mast Cell Leukemia
The purpose of this study was to determine the efficacy and safety of twice daily (bid) oral midostaurin in patients with Aggressive Systemic Mastocytosis (ASM) or Mast Cell Leukemia (MCL) with or without an Associated…
- Trial name
- NCT00782067
- Testing
- Midostaurin (PKC412)
- Where
- 29 sites in United States, Australia and 10 more
- Volunteers
- 116 people
- Sponsor
- Novartis Pharmaceuticals
Diabetes Mellitus
Point-of-care Health Literacy and Activation Information to Improve Diabetes Care
This hybrid effectiveness/implementation trial will be conducted in two phases over four years. In Phase 1, the investigators will evaluate the process of implementing a collaborative, diabetes goal-setting intervention…
- Trial name
- EPIC (NCT01876485)
- Testing
- Empowering Patients in Chronic Care (EPIC), Enhanced Usual Care (EUC)
- Where
- 3 sites in United States
- Volunteers
- 280 people
- Sponsor
- VA Office of Research and Development