Clinical trials: Behavioral Dynamics, open to volunteers
Depression, Anxiety, Emotional Disorders
Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress
The goal of this clinical study is to learn how Mindfulness Intervention for Emotional Distress (MIED) helps people with emotional distress and how their symptoms and psychological patterns change over time.
- Trial name
- NCT07280481
- Testing
- Mindfulness Intervention for Emotional Distress (self-guided version)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University
Relational and Communication Conflicts Between Adolescents and Their Families
Addressing Relational and Communication Conflicts in Families With Adolescents.
Adolescence is a stage characterized by intense emotional and social changes. Young people experience emotions more intensely, but they do not always have the necessary tools to recognize, understand, and regulate them properly.
- Trial name
- ARACC-FA (NCT07584421)
- Testing
- Reflective Workshop
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Pediatric Cancer, Coping Behavior
Coping and Attachment in Pediatric Oncohematology
Cancer can be a traumatic and particularly salient experience in a person's history. The ways in which the pediatric patient copes with it depend on the interaction of several factors present in his or her life context, primarily…
- Conditions
- Pediatric Cancer, Coping Behavior, Relationship, Parent Child
- Trial name
- CopAt (NCT06858163)
- Where
- 3 sites in Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Bipolar Disorder I or II, Healthy (Controls)
Decoding Emotional Dynamics in Bipolar Disorder
The goal of this neuroimaging study is to investigate how emotional states fluctuate in people with bipolar disorder (BD) compared to healthy controls, and to understand the neural mechanisms driving mood instability.
- Trial name
- NCT07221864
- Testing
- Think and Regulate Affective State Task
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Depression, Major Depressive Disorder
Rapid Antidepressant Dynamics in Acute Neuromodulation Treatments
The goal of this clinical trial is to learn how different types of non-invasive brain stimulation affect mood and brain function in adults with major depressive disorder (MDD).
- Trial name
- RADIANT (NCT06976840)
- Testing
- Intermittent theta burst stimulation, Continuous theta burst stimulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Marta Peciña, MD PhD
Substance Use Disorder (SUD), Treatment Adherence
Dynamic Multilevel Processes of Recovery in Therapeutic Communities in Mexico (DICO Model)
This study aims to develop and empirically evaluate the Dinámica Integral Conductual Comunitaria (DICO) model, a multilevel framework that conceptualizes recovery from substance use disorders as a dynamic process emerging from…
- Trial name
- DICO (NCT07588516)
- Testing
- Ecological Momentary Assessment (EMA)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Under The Tree Therapeutic Community
Mindfulness Skills, Psychosocial Education
Mindfulness Intervention for Psychological and Family Dynamics in Children With Body-Focused Repetitive Behaviors
This is a single-center, randomized, controlled intervention study designed to evaluate the effectiveness of mindfulness intervention on reducing body-focused repetitive behaviors (BFRBs) in children aged 8-18, such as…
- Trial name
- MIND-BFRB (NCT06777212)
- Testing
- Mindfulness Training Program, Psychosocial Education Program
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Smoking, Tobacco Use
Linking Brain Network Dynamics to Imminent Smoking Lapse Risk and Behavior
Most attempts to quit smoking end in relapse, or a return to regular smoking. One of the biggest threats to cessation is a lapse (i.e., any cigarette use during a quit attempt).
- Trial name
- NCT05572671
- Testing
- Laboratory task modeling smoking lapse behavior
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Penn State University
Depression, Anxiety
Hybrid Type 1 Randomized Pilot Trial of a Peer-led Family and Social Strengthening Group Intervention for Refugee Families
The proposed study draws on prior research to evaluate the feasibility, acceptability and explore preliminary effectiveness of Coffee and Family Education and Support, Version (CAFES2) using a pilot randomized type 1 hybrid…
- Conditions
- Depression, Anxiety, PTSD, Family Dynamics
- Trial name
- NCT06261463
- Testing
- CAFES2
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Illinois Chicago
Brain Plasticity
Effect of aiTBS on Intrinsic Spectral Dynamics and Task Performance
Aim 1: Measure local shifts in cortical spectral dynamics following aiTBS. Aim 2: Measure network-specific shifts in task performance following aiTBS.
- Trial name
- NCT07565207
- Testing
- TBS
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Family Dynamics, Trust in Healthcare System
Patient-clinical Linkages to Improve Trust and Engagement in Postpartum Healthcare
Maternal mortality in the United States is higher than in peer nations and has not decreased since 1990. Beyond mortality, severe maternal mortality impacts far too many women.
- Conditions
- Family Dynamics, Trust in Healthcare System, Family Structure, Health Literacy
- Trial name
- NCT06481631
- Testing
- The PEN-3 Intervention Model
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Jackson State University
Emotional Distress, Depression, Anxiety
Temporal Dynamics of Mindfulness Intervention for Emotional Distress: Daily Interventions and Assessments
This research aims to adopt a complex systems perspective to thoroughly examine the impact of online mindfulness interventions on changes in emotional distress, with a particular focus on the mechanisms of action.
- Trial name
- NCT06919406
- Testing
- Mindfulness Intervention for emotional distress(MIED）
- Volunteers
- 100 people
- Sponsor
- Peking University
Social Cognition, Personality Disorder
Neurocomputational Dynamics of Cooperation
The purpose of this study is to understand brain function, how people make decisions when they interact with others, and how brain function and behavior relate to personality traits.
- Conditions
- Social Cognition, Personality Disorder, Mental Health, Interpersonal Conflict
- Trial name
- COBRA (NCT07759973)
- Testing
- Social Learning Task Battery, Clinical Cohort, Social Learning Task Battery, Online Cohort
- Where
- United States
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity & Overweight, Depression Disorders
Physical Activity for Depressive Symptoms in Adults With Obesity: A Randomized Controlled Feasibility Trial
The goal of this clinical trial is to learn whether a supervised physical activity program can be successfully carried out for adults living with obesity and depression, and whether people are willing to take part in this kind of…
- Trial name
- NCT07836582
- Testing
- Supervised Physical Activity Program
- Where
- 3 sites in Canada
- Volunteers
- 26 people
- Sponsor
- Universite du Quebec en Outaouais
Depression
Systemic Couple Therapy for Marital Dynamics and Mental Health
The goal of this clinical trial (randomized controlled trial within a mixed-method study) is to learn whether Systemic Couple Therapy (SCT) can treat depression and improve relational functioning in married couples where at least…
- Trial name
- NCT07736508
- Testing
- Systemic Couple Therapy
- Volunteers
- 48 people
- Sponsor
- Shifa Tameer-e-Millat University
Burnout Risk
Burnout Intervention During War for Hospital Staff in Ukraine
The project endeavours to investigate the feasibility and acceptability of a psychoeducational training intervention for professional burnout and related psychological variables among both medical and non-medical workers in…
- Trial name
- NCT07620756
- Testing
- Burnout prevention
- Where
- Ukraine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Insulin Sensitivity
Physical Activity and Insulin Sensitivity Dynamics
The study investigates the role of one single bout of exercise in mediating enhancement of muscle insulin sensitivity following a single bout of exercise.
- Trial name
- NCT06776094
- Testing
- One-legged-knee extensor exercise, Insulin infusion, Muscle Biopsy Medication: Lidocaine
- Where
- Denmark
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
PTSD, Depression
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD.
- Conditions
- PTSD, Depression, Alcohol Use Disorder, Opioid Use Disorder
- Trial name
- NCT04356274
- Testing
- Participatory System Dynamics (PSD), Audit and Feedback (AF)
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research