Clinical trials: Behavioral Symptom
Suicide
Veterans Coping Long-term With Active Suicide
The proposed study seeks to test the efficacy of an intervention to reduce suicide behaviors in Veterans. The Veterans Coping Long Term with Active Suicide Program (CLASP-VA) is an innovative, telephone-based intervention that…
- Trial name
- CLASP-VA (NCT01894841)
- Testing
- Coping Long Term with Active Suicide (CLASP), Safety Assessment and Follow Up Evaluation
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Major
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
This study evaluates the safety and efficacy of brenipatide when administered with standard of care (SoC) compared to placebo plus SoC in delaying the return of major depressive symptoms.
- Trial name
- RENEW-MDD-1 (NCT07412756)
- Testing
- Brenipatide
- Where
- 181 sites in United States, Australia and 13 more
- Volunteers
- 1,000 people
- Sponsor
- Eli Lilly and Company
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and debilitating side effect of chemotherapy (CT), often requiring dose reductions or treatment interruptions, which can compromise efficacy of the planned CT…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQTmicrob (NCT06799351)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Stress, Psychological
Comparative Intervention Study of Stress Reduction in Corporate Health Management
Aim of the study is the evaluation of the effects (psychological and physiological) of an hrv-biofeedback training, a mindfulness training and a combination of both training methods for stress reduction.
- Trial name
- NCT02709551
- Testing
- HRV_Bfb, MBI, MBI_HRV_Bfb
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Anxiety, Depression
Digital Single Session Intervention for Youth Mental Health
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist…
- Conditions
- Anxiety, Depression, Conduct Disorder, Stress
- Trial name
- NCT05449002
- Testing
- Practicing the Opposite (PTO), Usual Clinical Care
- Where
- 5 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Harvard University
Antidepressive Agents
Wuling Powder for the Treatment and Underlying Mechanism of Depressive Symptoms in Patients With Parkinson's Disease
Depression is one of the most important nonmotor features of idiopathic PD（Parkinson's disease ）which may not just interfere with the motor symptoms of PD but can also cause immense personal suffering as well as decreased quality…
- Trial name
- NCT03195231
- Testing
- Wuling Powder
- Volunteers
- 120 people
- Sponsor
- Beijing Hospital
Immunodeficiency Virus, Human, Depressive Symptoms
Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa
The purpose of this study is to conduct a two-arm effectiveness trial in Cape Town, South Africa of a Xhosa-adapted, nurse-delivered, cognitive behavioral therapy (CBT) treatment for depression and adherence, integrated into the…
- Trial name
- NCT02696824
- Testing
- Cognitive Behavioral Therapy for Adherence and Depression
- Where
- 3 sites in United States, South Africa
- Volunteers
- 161 people
- Sponsor
- University of Miami
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
COPD, HIV/AIDS
High-quality COPD Care for People With Immune Dysfunction Through Proactive E-consults
This study examines an intervention to promote effective, evidence-based care and de-implement inappropriate therapies for COPD in HIV-infected (HIV+) patients.
- Trial name
- ACHIEVE (NCT03856879)
- Testing
- Proactive E-consult
- Where
- 7 sites in United States
- Volunteers
- 270 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Burnout, Professional
Integrative Self-care Approaches for HCP Wellbeing
The purpose of this pilot study is to assess the impact of a hospital-based integrative self-care program (e.g., a. Reiki and b.
- Trial name
- NCT05387746
- Testing
- Caring Science, Mindful Practice and Reiki Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Sleep Quality, Depression Disorders
The Relationship Between Power Sleep and Sleep Quality, Depression, and Stress Levels in University Students
This prospective cohort study aims to evaluate the effects of daily daytime power napping on sleep quality, depression, and perceived stress levels among healthy individuals.
- Conditions
- Sleep Quality, Depression Disorders, Stress, Psychological, Occupational Stress
- Trial name
- NCT07315269
- Testing
- Daytime Power Napping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- okkes zortuk
Parkinson Disease, Idiopathic, Freezing of Gait
Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson Disease
The present study involves patients with Parkinson Disease (PD) suffering from freezing of gait (FOG) and depressive symptoms. The main aim of the study is evaluating the efficacy of vortioxetine in reducing moderate/severe FOG…
- Conditions
- Parkinson Disease, Idiopathic, Freezing of Gait, Depression Not Otherwise Specified
- Trial name
- NCT06805266
- Testing
- Vortioxetine (tablet)
- Volunteers
- 40 people
- Sponsor
- Marianna Amboni
Multiple Sclerosis, Insomnia
A Digital Therapeutic to Improve Insomnia in Multiple Sclerosis: A Randomized Controlled Trial.
The goal of this randomized controlled trial is to test the effectiveness of digital cognitive behavioral therapy for insomnia (dCBT-I) compared with digital patient education about insomnia for people with Multiple Sclerosis…
- Trial name
- NorseMS (NCT06113666)
- Testing
- Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Digital patient education about insomnia (PE)
- Where
- Norway
- Volunteers
- 550 people
- Sponsor
- St. Olavs Hospital
Healthy Subjects
The Impact of Pain Neuroscience Education on Physical Therapy Students' Knowledge, Attitudes, Beliefs, and Behaviors Towards Pain: A Randomized Controlled Trial
This study investigates the effect of pain neuroscience education (PNE) on pain knowledge, attitudes, beliefs and behaviors among undergraduate physiotherapy students in Jordan
- Trial name
- NCT06821022
- Testing
- Pain Neuroscience Education, Red Flags Education
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Bipolar Disorder
FMRI Study of Brain Response Before and After Lithium Treatment in People With Bipolar Disorder
This study will assess the effects of bipolar disorder on brain activity and will determine if medication changes the brain activity in people with bipolar disorder.
- Trial name
- NCT00596622
- Testing
- Lithium
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Indiana University
COPD
Physical Activity Enhancement Using Pedometers in COPD
Physical activity is reduced in COPD affecting morbidity and mortality and the usual advice is not good enough to increase the physical activity level.
- Trial name
- NCT01739751
- Testing
- pedometers
- Where
- Chile
- Volunteers
- 90 people
- Sponsor
- University of Chile
Depression After Video-assisted Thoracoscopic Surgery
TAES Alleviate Post-VATS Depression
Depression can significantly affect postoperative rehabilitation quality and increase the mortality of patients who receive video-assisted thoracoscopic surgery (VATS).
- Trial name
- TAES (NCT06718231)
- Testing
- Transcutaneous electrical acupoint stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fuling Central Hospital of Chongqing City
Psychological Stress, Palliative Care
Visual Art Therapy on Caregiver Burden
This study aims to determine the effect of Zentangle practice on perceived caregiver burden, stress levels, and burnout among family caregivers of patients receiving palliative care.
- Conditions
- Psychological Stress, Palliative Care, Family Caregivers
- Trial name
- Visual art (NCT07702682)
- Testing
- Visual arts design training program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Affect, Alcohol Consumption
Automated Telephone Follow-up in the Swedish Prison and Probation Services
The purpose of this study is to investigate whether automated telephony may be used for daily assessments of paroled offenders, and whether a brief intervention based on these daily assessments may result in a more positive…
- Conditions
- Affect, Alcohol Consumption, Substance Abuse
- Trial name
- NCT01727882
- Testing
- Brief feedback, Daily assessments
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Skane
Major Depressive Disorder
Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression.
- Trial name
- NCT06786624
- Testing
- NBI-1065845
- Where
- 18 sites in United States
- Volunteers
- 200 people
- Sponsor
- Neurocrine Biosciences