Clinical trials: Behaviors, Health
Substance Use Disorder (SUD), Mental Health Disorder
Reentry Assist (R-Assist)
This project will aim to develop and pilot test, R-Assist, a mobile health application to support individuals with co-occurring substance use and mental health disorders (COD) in their recovery, who have recently released from a…
- Conditions
- Substance Use Disorder (SUD), Mental Health Disorder, Criminal Recidivism
- Trial name
- R-Assist (NCT06980233)
- Testing
- reentry assistance mobile health app
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Meaningful Measurement, Inc
Smoking Cessation
A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation
This will be an open-label, randomised, 2-treatment period, single-dose crossover study to determine the comparative bioavailability and renal elimination following single-dose administration of 3.0 mg cytisine in healthy smokers…
- Trial name
- NCT03509948
- Testing
- cytisine
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- Achieve Life Sciences
Infertility, Mental Health
Patient Empowerment Project (PEP) Study
The Patient Empowerment Project (PEP) will be integrated into the intake process at a fertility clinic to prepare clinical staff for any patient sensitivities or preferences and provide extra support if needed.
- Trial name
- PEP (NCT07725458)
- Testing
- Patient Empowerment Program (PEP)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Inception Fertility Research Institute, LLC
Mental Fatigue, Mental Stress
tAN for First Responders
This study is designed as an open label, single arm, decentralized clinical study in which first responders will receive transcutaneous auricular neurostimulation (tAN), which targets the auricular branch of the vagus nerve…
- Trial name
- NCT07109349
- Testing
- Sparrow Link
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Spark Biomedical, Inc.
Depression - Major Depressive Disorder, Anxiety
Validation of Accexible Screening and Self-Administered Activities for Emotional Well-Being in a University Hospital (UaDEC)
Major depressive disorder (MDD) and anxiety are increasingly prevalent among university student populations, yet early detection remains reliant on psychometric instruments tied to diagnostic criteria (e.g., PHQ-9, GAD).
- Trial name
- NCT07578155
- Testing
- AcceXible
- Where
- Mexico
- Volunteers
- 902 people, healthy volunteers welcome
- Sponsor
- Accexible
Smoking Cessation
Trial of Cytisine in Adult Smokers
This placebo-controlled Phase 2b trial is being conducted at sites within the United States (US) to evaluate the effectiveness cytisine dosage (1.5 mg, 3.0 mg) and administration schedule (commercial titration versus simplified 3…
- Trial name
- NCT03709823
- Testing
- Cytisine, Behavioral support
- Where
- 8 sites in United States
- Volunteers
- 254 people
- Sponsor
- Achieve Life Sciences
Anxiety Disorders
The Effects of Noninvasive Neuromodulation on Mental Wellness, Behavior, and Electrophysiology
The purpose of the study is to test the effects of brief, low-intensity transcranial focused ultrasound (TUS) on electrophysiological, behavioral, and cognitive markers related to anxiety disorders.
- Trial name
- NCT06169631
- Testing
- Gen0b
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sanmai Technologies PBC dba Sanmai
Psychological, Depression, Anxiety
The Effects of a Life Coaching Seminar on Gratitude and Psychological Well-Being
This study will consist of a randomized experimental group and a control group, In addition to the control and experimental group, there will also be a non-randomized motivated experimental group.
- Conditions
- Psychological, Depression, Anxiety, Psychological Stress, Mental Health Wellness 1
- Trial name
- NCT04172051
- Testing
- Tony Robbins Date with Destiny
- Where
- 3 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Depression, Anxiety
Effect of Two Probiotic Formulations on Mental Health and Mood Biomarkers in Adults With Depressive Symptoms
This is a 3-arm, parallel-group, randomized, double-blind, placebo-controlled pilot trial. Sixty adults presenting with depressive symptoms will be randomly allocated to one of 3 groups comprising (1) Bifidobacterium adolescentis…
- Trial name
- NCT05564767
- Testing
- B. adolescentis Bif-038, Lacticaseibacillus rhamnosus, LGG® and Bifidobacterium, BB-12®
- Where
- Australia
- Volunteers
- 62 people
- Sponsor
- Chr Hansen
Cigarette Smoking
A Smoking Cessation Study to Understand the Biological and Functional Changes After One Year of Smoking Cessation
The purpose of this study was to understand the biological and functional changes after one year of smoking cessation and to collect data on a broad range of biomarkers of exposure (BoExp) and biomarkers of effect (BoE).
- Trial name
- RIBESC (NCT02432729)
- Where
- 5 sites in United States, Germany and 3 more
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Mood, Depression Disorders
Technology Exposure and Child Health: Wellness Impact and Social Effects: An Observational Product Registry Study
The goal of this study is to understand how children's mobile device usage (smartphones or tablets), including social media use and online games, are related to their mental wellness and mental health, as well as some aspects of…
- Conditions
- Mood, Depression Disorders, Anxiety Disorders, Sleep
- Trial name
- TECHWISE (NCT06664944)
- Where
- United States
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- Aura
Anxiety, Depression in Adolescence
Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India
The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and/or depression in rural…
- Conditions
- Anxiety, Depression in Adolescence, Anxiety Disorder of Adolescence
- Trial name
- NCT07595029
- Testing
- Digital psychosocial tool
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wysa
Mental Health Wellness 1, Preterm Birth
Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
This randomized controlled trial will test an intervention called the Mastery Lifestyle Intervention (the MLI) that was developed from data of 1000+pregnant Hispanic women related to risks of preterm birth.
- Trial name
- MLI (NCT05012072)
- Testing
- The Mastery Lifestyle Intervention
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Microgen LLC
Engagement, Patient, Mood
SimpleC Wellness Platform With Social Robot Interaction
This implementation study will be conducted to test a Socially-Assistive Robot (SAR) system for residents in an Assisted Living environment. The goal of the SAR system is to enhance social engagement and connectedness.
- Conditions
- Engagement, Patient, Mood, Quality of Life, Aging
- Trial name
- NCT05296239
- Testing
- SimpleC Wellness Platform with Social Robot Interaction
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- SimpleC, LLC
Smoking Cessation
The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette
This three-group randomized double-blind placebo-controlled trial (N=180) will evaluate the impact of combination zonisamide and bupropion on the process of switching from combustible cigarettes (CCs) to an e-cigarette.
- Trial name
- NCT05205811
- Testing
- Bupropion, Zonisamide, E-cigarette
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Smoking
Study of TA-NIC to Assess the Efficacy and Safety of the Vaccine as an Aid to Smoking Cessation
Over 1 billion people worldwide smoke, resulting in an estimated 4 million deaths annually from smoking-related disease.1 Persistent and long-term smoking leads to an increased risk of cardiovascular damage, respiratory disease…
- Trial name
- NCT00633321
- Testing
- TA-NIC
- Where
- 9 sites in United States
- Volunteers
- 522 people, healthy volunteers welcome
- Sponsor
- Celtic Pharma Development Services
Vascular Access Complication
Prospective Feasibility Trial of AccuCath 2.25" Blood Control (BC) Placed in Difficult Access Patients in the Emergency Department
Study objective is to evaluate user preference, time for procedure, insertion success rates, complications, completion of therapy and dwell time of the AccuCath 2.25" BC device placed in difficult IV access patients in the…
- Trial name
- NCT02449798
- Testing
- AccuCath 2.25" BC Intravascular Catheter
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Chronic Kidney Diseases, Diabetes
KidneYou - Innovative Digital Therapy
The aim of the study is to assess the improvement of health in patients affected by CKD when they are exposed to non-pharmacological treatment strategies as nutritional program (NP), physical activity program (PA) and mindfulness…
- Conditions
- Chronic Kidney Diseases, Diabetes, Arterial Hypertension, Chronic Glomerulonephritis
- Trial name
- NCT05286632
- Testing
- KidneYou APP
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Advice Pharma Group srl
Adolescent Well-Being, Mental Health Wellness
Predict the Best Level of Care Placement for Each Child's Behavioral Health Needs - Efficacy Study
The purpose of this randomized clinical trial is to test the efficacy of a new clinical decision support tool, Placement Success Predictor (PSP).
- Trial name
- NCT06815562
- Testing
- Clinical team access to Placement Success Predictor (PSP) results
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Outcome Referrals, Inc.
Smoking Cessation, Tobacco Use Cessation
Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)
The primary study objective is to demonstrate the efficacy of dianicline as an aid to smoking cessation in cigarette smokers. The main secondary objectives are to assess the: craving for cigarettes, nicotine withdrawal symptoms…
- Trial name
- NCT00387946
- Testing
- SSR591813L (dianicline)
- Where
- 2 sites in United States, Canada
- Volunteers
- 630 people
- Sponsor
- Sanofi