Clinical trials: Behaviour
Dietary Habits
The PortionSize Smartphone App Pilot (PS Pilot)
The objective is to examine the preliminary validity, reliability and perceived participant satisfaction of the PortionSize app.
- Trial name
- PS Pilot (NCT04494971)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pennington Biomedical Research Center
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists: A Stepped-Wedge Trial
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT06547814
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Suicide, Attempted, Suicide and Depression
Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents
This project aims to examine the signal of efficacy of ketamine, a rapidly acting medication shown to decrease suicidality in adults in as short as hours or days, as opposed to weeks.
- Conditions
- Suicide, Attempted, Suicide and Depression, Suicide Threat
- Trial name
- TASK (NCT04592809)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder, Healthy Controls
Elucidating the Neurocircuitry of Irritability With High-Field Neuroimaging to Identify Novel Therapeutic Targets
The study is investigating dysfunctions in neurocircuitry in regards to irritability with healthy controls (HC) and individuals with Major Depressive Disorder (MDD) by performing MRIs.
- Trial name
- UNIKET (NCT05046184)
- Testing
- Ketamine Hydrochloride, Midazolam injection
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Rheumatoid Arthritis
Physical Activity in Patients With Rheumatoid Arthritis Treated With Adalimumab in Routine Clinical Practice
The purpose of this study was to evaluate physical activity and its changes in participants with rheumatoid arthritis (RA) who were treated with adalimumab therapy in clinical practice.
- Trial name
- PACE (NCT01756235)
- Volunteers
- 462 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Cigarette Smoker, Current Smoker
18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules
This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with indeterminate lung nodules.
- Conditions
- Cigarette Smoker, Current Smoker, Former Smoker, Multiple Pulmonary Nodules
- Trial name
- NCT03824535
- Testing
- Computed Tomography, Fludeoxyglucose F-18, Fluorine F 18 L-glutamate Derivative BAY94-9392
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Andrei Iagaru
Substance-Related Disorders
Behavioral Insights to Encourage Judicious Prescribing of Opioids
In collaboration with the San Diego Medical Examiner's Office and the State of California's controlled Substance Utilization Review and Evaluation System (CURES), the investigators propose to review opioid poisonings over the…
- Trial name
- NCT02790476
- Testing
- Letters
- Where
- United States
- Volunteers
- 851 people
- Sponsor
- University of Southern California
Healthy, Attention Deficit Hyperactivity Disorder
Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
The goal of this research is to understand the functioning of 'regulatory circuits' in the brain. We are also interested in how the medications methylphenidate and naltrexone affect these regulatory circuits.
- Trial name
- NMAS (NCT01993108)
- Testing
- Methylphenidate, Naltrexone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cocaine Use Disorder, Anxiety
Role of the Orexin Receptor System in Stress, Sleep and Cocaine Use
The purpose of this study is to determine the effectiveness of a medication called suvorexant in reducing anxiety, improving sleep, and reducing cocaine cravings or cocaine use.
- Trial name
- NCT02785406
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Health Care Utilization
Increasing Teen Access to Sexual and Mental Health Care
Investigators will form community partnership with community sites that will disseminate curated educational information on Sexual and Reproductive Health/Mental Health (SRH/MH).
- Trial name
- NCT05444855
- Testing
- Peer Leader Model
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Antimicrobial Resistance, Attitude to Health
Testing New Ways to Name Antimicrobial Resistance
This study aims to investigate the public's views on antibiotics and the impact of different ways to name the potential consequences of antibiotics not working in the future.
- Trial name
- NCT06356285
- Testing
- Presentation of Antimicrobial Resistance
- Where
- United Kingdom
- Volunteers
- 4,296 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Smoking, Tobacco Use
Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)
The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. E-cigarettes are classified by the US Food and Drug Administration (FDA) as a tobacco product, though…
- Trial name
- CONNECT (NCT03453385)
- Testing
- Electronic Cigarette
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Medication Adherence
Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.
The purpose of this project is to test whether an online pain medication intervention is a feasible and effective way to increase opioid pain medication safety.
- Trial name
- NCT01770314
- Testing
- Experimental
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Inflexxion, Inc.
Coronary Artery Disease
Cardiac Home Education and Support Trial (CHEST): A Pilot Study
Coronary artery bypass graft (CABG) surgery is performed more frequently on individuals who are older and sicker than in previous years.
- Trial name
- NCT00275340
- Testing
- Peer Support
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- University of Toronto
Nicotine Dependence, Smoking
N-acetylcysteine for Tobacco Use Disorder
The purpose of this study is to assess the effects of administering N-Acetylcysteine (NAC) to assist in initial cessation and/or relapse prevention in adult cigarette smokers.
- Trial name
- NCT02737358
- Testing
- N-acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Hemophilia A, Hemophilia B
An Institutional Pilot Study to Investigate Physical Activity Patterns in Boys With Hemophilia
This pilot project was developed to investigate subjective and objective data related to the patterns of physical activity participation among hemophilia patients (FVIII or FIX) between the ages of 5 and 18 years.
- Conditions
- Hemophilia A, Hemophilia B, Factor VIII Deficiency, Factor IX Deficiency
- Trial name
- HEPS (NCT02199717)
- Testing
- Accelerometer
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- The Hospital for Sick Children
Fasting
Electronic Nose Identification of Fasting and Non-fasting Breath Profiles
The investigators will study a noninvasive no risk process by which the investigators can quickly screen and assess for fasting and non-fasting states in individuals scheduled for routine endoscopy.
- Trial name
- Fast Breath (NCT02419976)
- Testing
- a breath analysis using the Aeonose, Aeonose
- Where
- United States
- Volunteers
- 879 people
- Sponsor
- Mayo Clinic
Depressive Symptoms, Substance-related Disorders
Intervention for Veterans With Depression, Substance Disorder, and Trauma
This study will compare two different types of psychotherapy for Veterans with depression, addiction, and a past traumatic experience.
- Conditions
- Depressive Symptoms, Substance-related Disorders, Posttraumatic Stress Disorders
- Trial name
- NCT00958217
- Testing
- Cognitive Processing Therapy-Modified (CPT-M), Integrated Cognitive Behavioral Therapy (ICBT)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- VA Office of Research and Development
Vaccine Refusal
Promoting Altruism to Enhance Vaccine Acceptance
Subjects enrolled in this study are eligible for the seasonal influenza vaccine. The purpose of this research study is to figure out if increasing individuals' awareness of the benefits of herd immunity, specifically to the local…
- Trial name
- NCT04568590
- Testing
- educational intervention
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pre Diabetes
Diabetes Prevention Program in Youth
The purpose of this study is to test the effectiveness of an out-of-school diabetes prevention program for youth (ages 7-15) with a family history of pre-diabetes or type 2 diabetes.
- Trial name
- NCT03042936
- Testing
- Insulin Superheroes Club Curriculum
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
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