Clinical trials: Behaviour
Caregiver Burden, Lewy Body Disease
VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia
The goal of this clinical trial is to evaluate the feasibility, acceptability, and initial efficacy of the VOCALE LBD+ intervention in caregivers of persons living with Lewy Body Dementia.
- Conditions
- Caregiver Burden, Lewy Body Disease, Stress, Skill, Coping
- Trial name
- NCT05622734
- Testing
- VOCALE LBD+
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Pain, Obesity
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Chronic pain contributes to declining health and function in older adults; effects that are intensified by obesity and sedentary (sitting) behavior.
- Conditions
- Chronic Pain, Obesity, Sedentary Lifestyle
- Trial name
- NCT03377634
- Testing
- MORPH
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Human Immunodeficiency Virus, Metabolic Syndrome
2-5 Intermittent Caloric Restriction in HIV
Background: Weight gain can lead to obesity and diabetes even in people living with human immunodeficiency virus (HIV). Researchers want to see if the technique intermittent calorie restriction can help overweight people with HIV…
- Trial name
- 2-5toWIN (NCT03489109)
- Testing
- Intermittent fasting, Standard of Care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Drug Dependence
Oxytocin and Cognitive Behavioral Therapy in Drug Dependence
Background: The therapeutic alliance between therapist and patient may contribute to favorable outcomes in all types of psychotherapy, including cognitive behavioral therapy (CBT) for drug dependence.
- Trial name
- NCT00975416
- Testing
- Cognitive Behavioral Therapy, Intranasal Oxytocin
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Depression, Anxiety
Healthy Minds Program App Dosage
The study will evaluate the effectiveness of the Healthy Minds Program (HMP) meditation app on participants experiencing depression and/or anxiety.
- Conditions
- Depression, Anxiety, Psychological Distress
- Trial name
- NCT05229406
- Testing
- HMP app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Wisconsin, Madison
Sedentary Behavior, Cardiovascular Risk Factor
Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System
Prolonged sitting may pose a public health risk through its effects on the cardiovascular system, and may lead to impaired whole-body cardiovascular health, which includes both vascular and cerebrovascular function.
- Conditions
- Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change
- Trial name
- NCT04207333
- Testing
- Mental Arithmetic Test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Hyperactivity Disorder
CONCERTA Lab School Study
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with Attention Deficit Hyperactivity Disorder…
- Trial name
- NCT00799487
- Where
- 3 sites in United States
- Volunteers
- 89 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment
Brief Summary: This study will compare the effectiveness of cognitive behavioral therapy (CBT), lisdexamfetamine (LDX), and the combination of CBT and LDX for the treatment of binge-eating disorder in patients with obesity.
- Trial name
- NCT03924193
- Testing
- Lisdexamfetamine Dimesylate, Cognitive-Behavioral Therapy, Combination LDX and Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Yale University
Bipolar Depression
The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder
The primary objective of this 15-week clinical trial is to test the hypothesis that treatment with two proven mitochondrial enhancers, acetyl-L-carnitine (ALCAR) and α-lipoic acid (ALA), has significantly greater efficacy than…
- Trial name
- NCT00719706
- Testing
- acetyl-l-carnitine PLUS alpha-lipoic acide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mclean Hospital
Breast Feeding, Infant Nutrition
Feeding My Baby - A National WIC Study
The goal of the study is to be a current examination of infant and toddler feeding practices among families receiving WIC services.
- Conditions
- Breast Feeding, Infant Nutrition, Childhood Obesity, Infant Feeding Patterns
- Trial name
- NCT02031978
- Volunteers
- 4,367 people
- Sponsor
- USDA Food and Nutrition Service
Behavior Problem
Tailoring CPP for the Foster Care Setting
The primary objective of this study is to tailor the Chicago Parent Program, an evidence-based parent training program, for the foster care setting and pilot the content in two cohorts of foster and kinship caregivers (Gross et…
- Trial name
- CPP-FC (NCT05856435)
- Testing
- Chicago Parent Program for Foster Care
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Low Back Pain, Degenerative Disc Disease
Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms
Opioids are frequently prescribed for chronic low back pain (CLBP). Psychiatric illness, such as high levels of depression and anxiety symptoms, is a common co-occurrence in chronic pain patients (and is termed comorbid negative…
- Conditions
- Chronic Low Back Pain, Degenerative Disc Disease, Depression, Anxiety
- Trial name
- NCT01502644
- Testing
- Oxycodone, Morphine
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Brigham and Women's Hospital
Rare Diseases
FACE for Children With Rare Diseases
Children with ultra-rare or complex rare diseases are routinely excluded from research studies because of their conditions, creating a health disparity.
- Trial name
- FACE-Rare (NCT04855734)
- Testing
- FAmily CEntered (FACE) pACP Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Depression
Meditation Accelerated Brain Stimulation for Depression
Repetitive Transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region.
- Trial name
- MediTMS (NCT04586699)
- Testing
- Medi1TMS, Medi2TMS
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of California, San Diego
HIV, AIDS
Effectiveness of a Smoking Cessation Algorithm Integrated Into HIV Primary Care
To determine the efficacy of an algorithm designed to recommend smoking cessation-related pharmacotherapy options to the primary care providers of smokers living with HIV/AIDS.
- Conditions
- HIV, AIDS, Smoking Cessation
- Trial name
- NCT03670316
- Testing
- Algorithm Treatment, Quitline only
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- University of Alabama at Birmingham
Opioid Abuse, Unspecified
Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges
The opioid epidemic has had a tremendous negative impact on the health of persons in the U.S. The objective of the trial 1 of Application of Economics \& Social psychology to improve Opioid Prescribing Safety (AESOPS-T1), is to…
- Trial name
- AESOPS-T1 (NCT04477304)
- Testing
- Opioid Naive, OR, At-risk for long-term use, OR, Long-term opioid recipient
- Where
- United States
- Volunteers
- 555 people
- Sponsor
- University of Southern California
Carcinoma, Renal Cell
Mobile Intervention - Physical Activity in Cancer Treatment
Aim 1. Determine the feasibility and acceptability of the proposed mobile technology intervention to increase physical activity patients receiving treatment for renal cell carcinoma. Aim 2.
- Trial name
- NCT03671304
- Testing
- Fitbit Versa
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Texas Southwestern Medical Center
Homeless Persons
Effect of a Rent Subsidy and Mentoring on Youth Transitioning Out of Homelessness
Compared to the vast amount of literature about the risk factors associated with young people entering and becoming entrenched in homelessness, much less is known about how to facilitate and sustain transitions off the streets.
- Trial name
- NCT03779204
- Testing
- Mentorship, Rent Subsidies
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Stress Disorders, Post-Traumatic, Depressive Symptoms
Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women
Posttraumatic stress disorder (PTSD) is a major public health concern that disproportionately effects minorities and those with low-socioeconomic status, such as homeless women, creating a critical health disparity.
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Symptoms, Hydrocortisone, Substance Use
- Trial name
- NCT04605198
- Testing
- Modified Mindfulness-based Stress Reduction, Health Promotion Wellness Classes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- University of California, Los Angeles
Smoking Cessation
Spanish-Language Smoking Cessation Trial
Results of a recently completed National Cancer Institute (NCI) funded trial of an intervention, Forever Free: Stop Smoking for Good, revealed high efficacy throughout the 24- month follow-up period, further supporting the…
- Trial name
- NCT02945787
- Testing
- Spanish-Language Version of the Stop Smoking for Good, NCI-Produced Spanish-language Self-help Booklet
- Where
- United States
- Volunteers
- 1,417 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
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