Clinical trials: Behaviour
Insomnia Chronic, Fecal Microbiota Transplantation
The Efficacy and Safty of FMT in Patients With CID
This clinical trial aims to learn about the efficacy of fecal microbiota transplantation in patients with chronic insomnia disorder.
- Conditions
- Insomnia Chronic, Fecal Microbiota Transplantation, Sleep Disorder, Depression
- Trial name
- NCT05917379
- Testing
- fecal microbiota, synbiotics
- Where
- 7 sites in China
- Volunteers
- 80 people
- Sponsor
- Peking University Sixth Hospital
Lung Cancer
Training Effects Following Resection Surgery in Patients With Lung Cancer
The purpose of this study is to determine the potential benefits resulting from a specific training on exercise tolerance and muscle function at the medium and long-time, as well as study its effects on plasmatic mediators…
- Trial name
- EMITOR (NCT01771796)
- Testing
- Aerobic and muscle resistance training
- Where
- 2 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Parc de Salut Mar
Rumination Disorder
A Pilot Study of Cognitive-Behavioral Therapy for Rumination Disorder (CBT-RD)
The primary aim of this study is to pilot cognitive behavioral therapy (CBT-RD) for 10 individuals ages 10 and older who have rumination disorder
- Trial name
- NCT03062696
- Testing
- CBT-RD
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Primary Insomnia
Sleep Homeostasis in Primary Insomnia
About 10% of the population is believed to suffer from Primary Insomnia. It is also believed that people with chronic insomnia have a sleep system that is essentially out of alignment (we call this "homeostatic dysregulation").
- Trial name
- NCT00256503
- Testing
- Cognitive-Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Extraterrestrial Habitation Systems, Lunar Surface Habitation
A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface
This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the…
- Conditions
- Extraterrestrial Habitation Systems, Lunar Surface Habitation, Lunar Water-Ice Resource Assessment, In-Situ Resource Utilization (ISRU)
- Trial name
- LUMEN-HAB (NCT07546461)
- Testing
- Habitat Systems Evaluation, Water-Ice Resource Utilization Assessment, EVA and Mobility Operations
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Depression, Anxiety, Mental Health Issue
Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety
A digital mental health intervention (BetterHelp, Mountain View, CA) provides users with access to online therapy care for treatment of depression and anxiety.
- Conditions
- Depression, Anxiety, Mental Health Issue, Mental Health Wellness 2
- Trial name
- NCT07081061
- Testing
- BetterHelp
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Teladoc Health
Depression
The ISLAND Study: InSuLa Assessed Needs for Depression
While there are many effective options for treating a major depressive episode, there are no clinical markers that predict the likelihood of remission with an initial trial of either an antidepressant medication or psychotherapy.
- Trial name
- ISLAND (NCT02137369)
- Testing
- Selective serotonin re-uptake inhibitor, Cognitive Behavioral Therapy, Combination treatment (SSRI + CBT)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Emory University
Adherence, Medication, HIV Prevention
Pharmacy-based PrEP for Young Women Who Sell Sex in Zimbabwe
Pharmacy-based PrEP for Young Women who Sell Sex in Zimbabwe is a cluster-randomized control trial and pilot study co-led by Dr.
- Trial name
- TOPAZ (NCT06348069)
- Testing
- Pharmacy-based PrEP refill and gift voucher, Control (Standard of care)
- Where
- Zimbabwe
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Alcohol Dependence, Depression
The MEADOW PROJECT (Mending the Effects of Alcohol and Depression on Women) and The Bridge Program (Connecting Recovery Treatment and Behavioral Health)
The aim of this study is to evaluate an interpersonally-focused intervention (Interpersonal Psychotherapy) for women with co-occurring alcohol dependence and depression.
- Trial name
- MEADOW/Bridge (NCT00851669)
- Testing
- Interpersonal Psychotherapy for Co-occurring Alcohol Dependence and Major Depression (IPT-ADMD), Treatment as Usual
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Rochester
Kidney Transplant Failure and Rejection, Gender
Sex Impact on Long-term Outcomes of LDKT
The impact of donor and recipient gender combination on kidney transplant outcomes has been reported in several studies. The results vary greatly due to different factors, such as minor histocompatibility antigens, nephron…
- Trial name
- NCT06016283
- Where
- Netherlands
- Volunteers
- 1,276 people
- Sponsor
- Erasmus Medical Center
Hyperphagia, Prader-Willi Syndrome
Prader-Willi Syndrome and Appetite
Excessive weight gain is a cardinal feature of Prader-Willi syndrome (PWS) for which there is presently no effective treatment. It is caused by increased appetite, decreased perception of satiety and obsessive and compulsive…
- Trial name
- NCT00175305
- Testing
- Sandostatin LAR
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Depression, Suicide
Reaching Out to Distressed Medical Residents, Fellows and Faculty
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and…
- Trial name
- NCT02010866
- Testing
- counseling
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Smoking Cessation, Thoracic Surgery
Smoking Cessation in the Surgical Pathway Before Major Lung Surgery
This is a feasibility study of a personalised, integrated smoking cessation in the surgical pathway in patients undergoing major elective thoracic surgery when compared to usual care of standard community/hospital based NHS…
- Trial name
- MURRAY (NCT04190966)
- Testing
- Integrated Behavioural therapy, Integrated Pharmacotherapy, Integrated Web-based application
- Volunteers
- 120 people
- Sponsor
- University of Birmingham
Physical Exercise Behavior (Liking/Aversion)
Molecular and Functional Neurobiology of Physical Exercise
In this study, we use positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to study brain mechanisms that contribute to physical exercise-induced reward.
- Trial name
- EXEBRAIN (NCT02615756)
- Testing
- Exercise
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sedentary Behavior, Cardiometabolic Risk Factors
Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health
The purpose of this Phase 1 research study is to answer two questions: (1) How frequent should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these breaks in…
- Conditions
- Sedentary Behavior, Cardiometabolic Risk Factors, Blood Pressure, Glucose
- Trial name
- NCT05353322
- Testing
- Sedentary Break (Walking) Condition, Sitting (Control) Condition, Controlled Diet
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breastfeeding Self-Efficacy Attitude to Health Postpartum Period Primiparity
Client-Centered Breastfeeding Support: Effects on Primipara Mothers in a Randomized Trial Breastfeeding Self-Efficacy, Attitudes, and Problems in Primiparous Mothers: A Randomized Controlled Trial
Study Description The goal of this randomized controlled trial is to examine the effects of a client health behavior interaction model-based breastfeeding support program on breastfeeding self-efficacy, attitudes, and problems in…
- Trial name
- NCT06446362
- Testing
- IMCHB-Based Breastfeeding Support Program, Standard Breastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Non-Small Cell Lung Cancer (NSCLC)
Digital Lifestyle Intervention for Lung Cancer Survivors
The aim of this study is to assess the efficacy of a digital lifestyle intervention in non-small cell lung cancer (NSCLC) survivors on health-related quality of life (HRQoL) over three months.
- Trial name
- QUALUCA (NCT05819346)
- Testing
- Lifestyle
- Where
- 4 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- Kai-Uwe Schmitt, PhD, MEng, ICID
Circadian Rhythm
Effect of Circadian Rhythm on Brain NAD Measured by Phosphorus Magnetic Resonance Spectroscopy at 7 Tesla
The Discovery of the circadian clock first established a genetic basis for behavior, and our understanding of circadian rhythm (CIR) has since expanded to provide molecular insights into physiology and disease.
- Trial name
- ChronoBrain (NCT05093088)
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Rumination, Stress, Psychological
Testing a Digital Intervention for Adolescents
Teen participants (ages 13-17) will be randomly assigned to either an experimental (the Happify Teens digital platform), or a waitlist control group. The study includes an 8-week intervention period and a 1-month follow up period.
- Trial name
- NCT04567888
- Testing
- Happify Teens
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- Happify Inc.
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
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