Clinical trials: Behavioural Disorder
Attention Deficit Hyperactivity Disorder
Genetic Liability in the Brain Morphology of Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder (ADHD) is a heritable psychiatric disorder with onset in childhood. Twin and adoption studies indicate that additive genetic factors explain up to 80% of the variance underlying…
- Trial name
- NCT00161161
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Attention-Deficit/Hyperactivity Disorder (ADHD)
Virtual Reality for Parent Training Intervention
Previous research has shown how parental responses can affect ADHD symptoms by triggering dysfunctional cyclic processes. Therefore, it may be useful within rehabilitative treatments to include parent training (PT).
- Trial name
- NCT05809388
- Testing
- Parent training, Virtual Reality-assisted PT sessions
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Morbid Obesity, Bariatric Surgery
Registry on Obesity Surgery in Adolescents
While bariatric surgery is established as a safe and effective alternative with well-defined risks for severely obese adults, little has been published on its use in children.
- Conditions
- Morbid Obesity, Bariatric Surgery, Adolescent Obesity
- Trial name
- ROSA (NCT03203161)
- Testing
- bariatric surgery
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Insomnia
Cognitive-Behavioural and Hypnotic Treatment of Chronic Primary Insomnia Among the Elderly
The present study examines the short- and long-term clinical efficacy of cognitive-behavior therapy and pharmacological treatment in patients suffering from late-life primary insomnia.
- Trial name
- NCT00295386
- Testing
- Cognitive behavior therapy (CBT), Zopiclone
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bergen
Autistic Disorders Spectrum, Adhd
Studies of Brain and Body Interaction
The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic…
- Conditions
- Autistic Disorders Spectrum, Adhd, Asperger Syndrome, Alzheimer Disease
- Trial name
- NCT03672266
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers University
REM Sleep Behavior Disorder
Efficacy and Safety of Melatonin and Clonazepam for IRBD
This study aimed to evaluate influence of melatonin or clonazepam treatment on symptom and polysomnographic parameters in patients with idiopathic REM sleep behavior disorder.
- Trial name
- NCT03255642
- Testing
- Melatonin 2mg, ClonazePAM 0.5 MG
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Attention Deficit Hyperactivity Disorder (ADHD), Impulsive Aggression
Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD
The purpose of this study was to evaluate the effect of 4-week SPN-810 treatment on brain functioning in patients aged 8-12 years with ADHD and associated feature of impulsive aggression (IA).
- Trial name
- NCT03638466
- Testing
- Functional Magnetic Resonance Imaging (fMRI), Magnetic Resonance Spectroscopy (MRS), Point Subtraction Aggression Paradigm (PSAP) Task
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
ADHD
Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17
The main aim of this study is to evaluate the long-term maintenance of efficacy of LDX after administered to children and adolescents aged 6-17 with ADHD for at least 6 months
- Trial name
- NCT00784654
- Testing
- Lisdexamfetamine dimesylate (LDX)
- Where
- 51 sites in United States, Belgium and 7 more
- Volunteers
- 276 people
- Sponsor
- Shire
ADHD
Multimodal Biomarkers Predicting Medication-Induced Adverse Effects in Children With ADHD
To build a multimodal model combining neuropsychological, neurophysiological, and metabolomic measures to identify biomarkers predicting MPH-induced adverse effects and their underlying mechanisms, supporting individualized risk…
- Trial name
- NCT07900451
- Testing
- methylphenidate
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
ADHD
Cognitive Remediation in ADHD Children : Comparison Between Three Therapeutic Strategies : Cognitive Remediation With a Virtual Classroom Software and Methylphenidate and Supportive Psychotherapy
The Attention Deficit Disorder with or without Hyperactivity (ADHD) is one of the most frequently found disorder in children. It is characterized by a triad of symptoms involving attention deficit, hyperactivity and impulsivity…
- Trial name
- RECOGNITA (NCT01821170)
- Testing
- Methylphenidate, cognitive remediation, supportive psychotherapy
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
Dementia With Lewy Bodies, Parkinson Disease
5-HT RBD REM Sleep Behavior Disorder
This project will test the hypotheses that people with 5-HT RBD have systemic alpha- synuclein pathology, prodromal DLB signs, and brainstem lesions in regions that control REM sleep.
- Conditions
- Dementia With Lewy Bodies, Parkinson Disease, REM Sleep Behavior Disorder
- Trial name
- NCT06467461
- Testing
- Skin biopsy, Speech testing, Ultra high field 7T MRI
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anxiety, Depression
Evaluating Knowledge Insight Tools (KIT) for Reducing Anxiety and Low Mood in UK Secondary School Students
Background and Study Aims: Secondary school students are reporting unprecedented levels of anxiety and mood difficulties. To ensure that the needs of all young people are met, there is a need to evaluate more accessible forms of…
- Conditions
- Anxiety, Depression, Internalizing Problems, Low Mood
- Trial name
- NCT06188962
- Testing
- CBT-informed school-based counselling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University College, London
Mental Retardation
"Cognitus & Moi": a New Cognitive Remediation Tool
Holders children with intellectual disabilities have great difficulty in adapting to social situations and relationships.Cognitive impairment associated with intellectual disability are important factors to understand their…
- Trial name
- COGNITUS (NCT02797418)
- Testing
- Cognitive remediation program
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Hôpital le Vinatier
Feeding Behaviors, Lack of Satiety
Metabolic and Neurofunctional Responses to Breakfasts
This study aims at assessing the effects of glucose and different types of breakfast on metabolic and neurofunctional responses in healthy individuals.
- Conditions
- Feeding Behaviors, Lack of Satiety, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT02897570
- Testing
- Glucose, Milk & Cereals, Milk, apple & snack
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
ADHD, Psychiatric Health
El Faro: Addressing Mental Health Inequities Among Latinx Children With ADHD in Durham
Study team members from El Futuro in Durham, North Carolina have created an intervention called El Faro. El Faro helps Latinx families of children with ADHD understand and cope with the stress and difficulties presented by the…
- Trial name
- NCT05928182
- Testing
- El Faro Treatment Intervention
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Duke University
Treatment Resistant Depression (TRD)
Risk-Targeted Behavioural Activation for the Management of Treatment-Resistant Depression.
Depression is the leading cause of disability worldwide. Major Depressive Disorder (MDD) is the most common diagnosis made for individuals seeking treatment for depression.
- Trial name
- NCT06729580
- Testing
- Behavioural Activation
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McGill University
Sensory Processing Disorder, Autism Spectrum Disorder
Pediatric Aquatic Occupational Therapy for Children With Sensory Processing Challenges
Children with sensory processing challenges participated in an 8-week play-based aquatic program addressing goals on behavior, sensory, and participation.
- Conditions
- Sensory Processing Disorder, Autism Spectrum Disorder, ADHD
- Trial name
- NCT06484946
- Testing
- aquatic occupational therapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Kristen Pataki
Covid19
Using Text Messages to Improve COVID-19 Vaccination Uptake
COVID-19 vaccinations significantly reduce the risk of getting seriously ill or dying from COVID-19. Since December 2020, the UK has rolled out vaccinations according to the Joint Committee for Vaccinations and Immunity (JCVI)…
- Trial name
- NCT04895683
- Testing
- Text message content
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Attention Deficit Hyperactivity Disorder
Cognitive and Behavioral Effects of Sleep Restriction in Adolescents With ADHD
Adolescents with attention-deficit/hyperactivity disorder (ADHD) obtain less sleep than their typically developing peers. Observational studies indicate that inadequate sleep is correlated with impairment in adolescents with…
- Trial name
- NCT02732756
- Testing
- Healthy Sleep Duration, Shortened Sleep Duration
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention-Deficit Hyperactivity Disorder (ADHD)
PDC-1421 Treatment in Adult Patients With ADHD
Part II is a double-blind, randomized, parallel-group, placebo-controlled study. The primary objective of this trial is to determine the effective doses and treatment period of PDC-1421 Capsule in subjects with ADHD.
- Trial name
- NCT05202327
- Testing
- PDC-1421 Capsule
- Where
- 6 sites in United States, Taiwan
- Volunteers
- 99 people
- Sponsor
- BioLite, Inc.
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