Clinical trials: Behavioural Disorder
Insomnia, Breast Cancer
Impact of Cognitive Behavioural Therapy for Insomnia on Endocrine Therapy Adherence
The aim of this study is to investigate the impact of cognitive behavioural therapy for insomnia on adherence to endocrine therapy medication in breast cancer survivors.
- Conditions
- Insomnia, Breast Cancer, Adherence, Medication, Quality of Life
- Trial name
- NCT05887297
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Strathclyde
Attention Deficit/Hyperactivity Disorder, ADHD
L-Threonic Acid Magnesium Salt (L-TAMS) in ADHD
This study is a 12-week, open-label pilot study to test the effects of MMFS-201-301 on cognition and function in adults with ADHD.
- Trial name
- NCT02558790
- Testing
- L-Threonic Acid Magnesium Salt (L-TAMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder
An Effectiveness and Safety Study Evaluating OROS Methylphenidate Hydrochloride (HCl), Ritalin (Methylphenidate HCl) and Placebo in Children With Attention Deficit Hyperactivity Disorder
The purpose of this study is to provide data on the effectiveness of the OROS Methylphenidate Hydrochloride (HCl) formulation compared to placebo and standard immediate-release Ritalin with respect to improving attention and…
- Trial name
- NCT00269776
- Testing
- OROS (methylphenidate HCl), Ritalin (methylphenidate)
- Sponsor
- Alza Corporation, DE, USA
Neurodegenerative Diseases, Parkinson Disease
Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
It is not known what causes Parkinson's disease and what makes it worsen over time. Research conducted in the past few years has highlighted the possible role of inflammation on this process but its actual mechanisms are still…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
- Trial name
- NCT05205291
- Testing
- Lipopolysaccharide, PET/MR with [11C]PBR28
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Insomnia
Cognitive Behavioural Therapy for Insomnia for Chinese Adults: a RCT
Background: Insomnia is a common mental problem, where people experienced difficulty falling asleep, problem maintaining asleep and early morning awakening.
- Trial name
- CBTI (NCT04653155)
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Hospital Authority, Hong Kong
Depression in Adolescence, Depressive Disorder
Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With Depression
Depressive Disorders constitute an increasing global health concern and available treatments for young people have not been sufficiently effective in haltering this trend.
- Conditions
- Depression in Adolescence, Depressive Disorder, Dysthymia and Chronic Depression
- Trial name
- TARA (NCT04747340)
- Testing
- Training for Awareness Resilience and Action (TARA), Standard treatment
- Where
- 3 sites in Sweden
- Volunteers
- 136 people
- Sponsor
- Umeå University
Attention Deficit Disorder With Hyperactivity
Evaluation of Brain Neurotransmitter Levels in Adults With ADHD, Before and After Stimulant Treatment
Background: Attention deficit hyperactivity disorder (ADHD) is one of the most prevalent neurobiological brain disorders. Diagnosis of ADHD in adults is complex and subjective.
- Trial name
- ADHD (NCT04823364)
- Testing
- Neurotransmitters evaluation by MRS
- Where
- 2 sites in Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weizmann Institute of Science
Attention Deficit Hyperactivity Disorder
Open-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Pediatric Participants With Attention-deficit Hyperactivity Disorder (ADHD)
With the pharmacokinetics (PK) of centanafadine currently being evaluated in adults. The PK of extended-release centanafadine may differ in children compared to adults due to physiological differences in the gastrointestinal…
- Trial name
- NCT04081363
- Testing
- Centanafadine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Developmental Delay, Preschool Children
Effects of Fairytales on Preschool Children With Attention Deficit Hyperactivity Disorder
Under traditional rehabilitation programs, investigate the additional effects of individualized fairytales on preschool children with Attention Deficit Hyperactivity Disorder with developmental delays.
- Conditions
- Developmental Delay, Preschool Children, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05502536
- Testing
- Traditional rehabilitation programs with Individualized fairytales class
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University
Attention Deficit Hyperactivity Disorder, Substance Abuse
Atomoxetine for Attention Deficit Hyperactivity Disorder in Adolescents With Substance Use Disorder
The purpose of this study is to find out whether atomoxetine (also called Strattera) helps teenagers (12-19) with Attention Deficit Hyperactivity Disorder (ADHD) and drug/alcohol problems.
- Trial name
- NCT00399763
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Dementia
REspectful CAring for the AGitated Elderly
The treatment of Behavioural and Psychological Symptoms of Dementia (BPSD) continue to raise difficult problems. Both the pharmacologic and non-pharmacologic therapies often fail to achieve the expected results.
- Trial name
- RECAGE (NCT03507504)
- Testing
- SCU-B
- Where
- 12 sites in Belgium, France and 5 more
- Volunteers
- 500 people
- Sponsor
- Fondazione Europea di Ricerca Biomedica Ferb Onlus
Attention Deficit Hyperactivity Disorder
Lab School Day Study for CONCERTA of Older Children With ADHD
The purpose of this trial is to determine if the study medication, CONCERTA (methylphenidate HCl), is safe and effective in improving academic performance and behavior in children with attention deficit hyperactivity disorder…
- Trial name
- NCT00799409
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Disruptive Behavior Disorders
The Parenting Young Children Check-up: Proof-of-Concept Trial
The Parenting Young Children Check-up (PYCC) is a 3-part system for parents of children with Disruptive Behavior Problems (DBPs).
- Trial name
- NCT04113304
- Testing
- Parenting Young Children Check-up (PYCC)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Wayne State University
ADHD
Classroom Study of SPN-812 in Children With ADHD
This study will evaluate the efficacy and safety of SPN-812, an extended-release formulation of viloxazine, compared to placebo in children in an analog classroom setting.
- Trial name
- NCT04016792
- Testing
- 200 mg SPN-812
- Sponsor
- Supernus Pharmaceuticals, Inc.
Depression, Bipolar Affective Disorder
The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems
The aim of this study is to examine the effect of a non-pharmacological transdiagnostic sleep intervention as add on to standard treatment for bipolar disorder, depression and attention deficit disorder.
- Conditions
- Depression, Bipolar Affective Disorder, Attention Deficit Disorder
- Trial name
- NCT05406414
- Testing
- Transdiagnostic sleep and circadian treatment, Active waitlist control group
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Attention Deficit Disorder With Hyperactivity
Effects of a Novel Neurofeedback Protocol on ADHD Subcomponents
Mounting evidence suggests that closed-loop brain-training, commonly known as neurofeedback (NFB), may represent a new therapeutic opportunity for patients with Attentional Deficit/Hyperactivity Disorder (ADHD), which manifests…
- Trial name
- NFB@HOME (NCT04408521)
- Testing
- NEUROFEEDBACK, CONTROL
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Mental Health, Neurodevelopment
Investigating the Impacts of Early Life Experience on the Brain & Behaviour
The aim of this study is to learn more about how early life experience influences the brain, behaviour, and the immune system later in life.
- Conditions
- Mental Health, Neurodevelopment, ADHD, Autism
- Trial name
- NCT06823492
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Posttraumatic Stress Disorder
Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Adults With PTSD
Up-to-date, no studies have examined the attentional, sensory and emotional processing (difficulties) among patients diagnosed with Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT05133804
- Testing
- Methylphenidate, Reboxetine
- Where
- 3 sites in Israel
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Depression, Schizophrenia
Norwegian Adult Mental Health Registry
"The Norwegian Adult Mental Health Registry" (NAMHR) is a medical quality register collecting and systematizing data on patients and their treatment in specialist mental health care for adults in Norway.
- Conditions
- Depression, Schizophrenia, Bipolar Disorder, Eating Disorders
- Trial name
- NAMHR (NCT06115200)
- Volunteers
- 150,000 people
- Sponsor
- Helse Stavanger HF
Attention Deficit/Hyperactivity Disorder (ADHD)
Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)
In contrast to mothers with Attention Deficit/Hyperactivity Disorder (ADHD), the impact of paternal ADHD in families and children with ADHD symptoms has not been studied, despite the prevalence of ADHD in males.
- Trial name
- NCT02675400
- Testing
- Vyvanse, Behavioral Parent Training, Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
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