Clinical trials: Behavioural Disorder
Attention Deficit Hyperactivity Disorder (ADHD)
Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 2)
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of SPN-810 in the treatment of impulsive aggression in patients with Attention-Deficit/Hyperactivity Disorder (ADHD) in conjunction with standard…
- Trial name
- NCT02618434
- Testing
- SPN-810 (18 mg), SPN-810 (36 mg)
- Where
- 32 sites in United States
- Volunteers
- 297 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
ADHD
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)
This study is a Phase 3, multi-center, randomized, 6-week, double-blind, placebo-controlled, parallel-group trial to assess the efficacy and safety of solriamfetol in adolescents aged 12 to <18 years with ADHD.
- Trial name
- NCT07717892
- Testing
- Solriamfetol Dose A, Solriamfetol Dose B
- Where
- 28 sites in United States
- Volunteers
- 468 people
- Sponsor
- Axsome Therapeutics, Inc.
Attention Deficit Hyperactivity Disorder
a Case-control Study of the Association Between Heavy Mental and Children With Attention Deficit Hyperactivity Disorder in Korea
Heavy metal has been reported that it can cause attention deficit and behavioral disturbance. The investigators hypothesis is that heavy metal is associated with children with attention deficit/hyperactivity disorder(ADHD).
- Trial name
- NCT01447004
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hallym University Medical Center
Acute Agitation, Behavioural Emergency
IM Olanzapine Versus Haloperidol or Midazolam
The purpose of this study is to determine whether intramuscular olanzapine is safer (fewer adverse events) and more effective (shorter time to sedation) than conventional haloperidol or midazolam when used in the management of…
- Trial name
- NCT02380118
- Testing
- Olanzapine, Haloperidol, Midazolam
- Where
- 6 sites in Hong Kong
- Volunteers
- 167 people
- Sponsor
- The University of Hong Kong
Attention Deficit Disorder With Hyperactivity
A Study of the Effectiveness and Safety of Prolonged-release Methylphenidate Hydrochloride in Adult Patients With Attention Deficit/Hyperactivity Disorder.
The purpose of this study is to evaluate the effectiveness and safety of three doses of prolonged-release methylphenidate (a central nervous system (CNS) stimulant) in adult patients with attention deficit/hyperactivity disorder…
- Trial name
- NCT00246220
- Testing
- methylphenidate hydrochloride
- Volunteers
- 402 people
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Auditory Hallucination, Verbal
Effects of Transcranial Direct Current Stimulation (tDCS) on Persistent Auditory Verbal Hallucinations in Schizophrenia
Many individuals with schizophrenia struggle with auditory verbal hallucinations (AVHs). In some cases, these AVHs can be resistant to medication treatment.
- Trial name
- NCT04222582
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Impulsive Behavior, Compulsive Disorder
Treating Impulsivity in Adults With Probiotics
A multicentre randomized double-blind placebo controlled parallel design (10 weeks) study investigating probiotic supplementation in highly impulsive adults (18-65 yrs; N=180).
- Conditions
- Impulsive Behavior, Compulsive Disorder, ADHD, Borderline Personality Disorder
- Trial name
- PROBIA (NCT03495375)
- Testing
- Treatment with a probiotic
- Where
- 3 sites in Germany, Hungary and 1 more
- Volunteers
- 180 people
- Sponsor
- Hospital Vall d'Hebron
Anxiety
Do Mind Ease Interventions Reduce Feelings of Acute Anxiety? A Randomised Controlled Trial
This study investigates the short-term effects of the MindEase app on anxiety levels.
- Trial name
- NCT05850975
- Testing
- intervention with this name in MindEase app, reading about anxiety
- Where
- United Kingdom
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Attention Deficit Hyperactivity Disorder
Software Treatment for Actively Reducing Severity of ADHD in Adults (STARS ADHD Adult)
The purpose of this study is to evaluate the effects of the videogame-like digital therapy on attentional functioning and symptoms in Adults diagnosed with ADHD.
- Trial name
- NCT05183919
- Testing
- Digital Treatment
- Where
- 14 sites in United States
- Volunteers
- 223 people
- Sponsor
- Akili Interactive Labs, Inc.
Atrial Fibrillation, Obesity
A Behavioural Weight Loss Intervention Delivered in Cardiac Rehabilitation for Patients With Atrial Fibrillation and Obesity
One-in-four Canadians will be diagnosed with an abnormal heart rhythm called atrial fibrillation (AF) in their lifetime. This is expected to double by 2050, owing to an aging population and increased age- and health…
- Trial name
- BeWEL IN CR-AF (NCT05600829)
- Testing
- BWLT+CR, CR-Only
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of Calgary
Attention-deficit/Hyperactivity Disorder
Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder
The purpose of this study is to determine effectiveness of Vyvanse compared to Concerta in adolescents with Attention-deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT01552902
- Testing
- Lisdexamfetamine dimesylate, Methylphenidate Hydrochloride
- Where
- 95 sites in United States, Canada and 3 more
- Volunteers
- 549 people
- Sponsor
- Shire
Attention-deficit Hyperactivity Disorder
The Efficacy of Equine Assisted Occupational Therapy for Children With Attention Deficit Hyperactivity Disorder (ADHD) on Cognitive-emotional Aspects, Daily Function and Participation
The goal of this clinical trial is to develop and validate an Equine Assisted Occupational Therapy Intervention for children aged 6-12 with Attention Deficit Hyperactivity Disorder.
- Trial name
- NCT05869253
- Testing
- The efficacy of Equine Assisted Occupational Therapy, for children with Attention Deficit Hyperactivity Disorder (ADHD) on cognitive-emotional aspects, daily function and participation
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel Aviv University
Adhd
Third Generation Cognitive Behavioural Therapy vs Treatment-as-usual for ADHD
The investigators hypothesize that the mindfulness Cognitive Behavioral Therapy program will lead to a reduction in attention deficit and hyperactivity disorder symptoms, anxiety and depression, and improve self-confidence…
- Trial name
- Hyper-mCBT (NCT03437772)
- Testing
- Mindfulness Cognitive Behavioral Therapy program
- Where
- 4 sites in France
- Volunteers
- 248 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
HIV Infections, Central Nervous System Diseases
Central Nervous System Disease in HIV-infected Children on HAART
This study will examine how HIV affects the brain and nervous system, learning, and behavior in children on highly active antiretroviral therapy (HAART).
- Trial name
- NCT00110331
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)
Attention Deficit Disorder With Hyperactivity
Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- TDA/H (NCT00684931)
- Testing
- Imaging
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Type 2 Diabetes, Circadian Rhythm
Determining Circadian Metabolic and Behavioural Rhythms in Patients with and Without Type 2 Diabetes
The goal of the present clinical descriptive study is to characterize and quantify the potential hormonal chronobiological differences between individuals with type 2 diabetes (T2D) and healthy age and weight-matched controls as…
- Trial name
- Cir-D-Brain (NCT06243172)
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
A
Effect Mindfulness Training on Attention, Hyperactivity and Emotion Regulation Among Children With ADHD:
Mindfulness training is a promising form of training for children with ADHD, as it focuses on attention and has gained empirical support as a complementary or alternative intervention.
- Trial name
- MindADHD (NCT06131190)
- Testing
- mindfulness training
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Circadian Rhythm Disorders, Cancer
A Feasibility Trial for Circadian Rest-activity Rhythm Disorders in Cancer (RALI)
Circadian rest-activity rhythm disorders are common in patients with cancer, particularly in advanced disease. A recent international e-Delphi study has outlined recommendations for the assessment and reporting of the disorder…
- Trial name
- NCT06329479
- Testing
- Cognitive behavioural therapy for Insomnia (CBT-I), Bright Light Therapy, Individualised activity plan
- Where
- 2 sites in Ireland
- Volunteers
- 30 people
- Sponsor
- University of Dublin, Trinity College
Attention Deficit Hyperactivity Disorder
An Open Label Phase I/II Study of the Safety and Dopamine Transporter Binding Properties of C-11 Altropane in Normal Human Subjects and in Subjects With ADHD
The primary objective of this study is to evaluate the Binding Potential in subjects with ADHD and adults without ADHD: the intent being to demonstrate that C-11 Altropane PET can be used to differentiate adults with ADHD from…
- Trial name
- NCT00302380
- Testing
- PET imaging using C-11 altropane as the ligand.
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
ADHD
Amphetamine Extended Release Tablets and Driving Performance in Subjects With Attention Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to assess the effect on driving performance of a single dose of amphetamine extended-release tablets (20 mg/tablet) compared with placebo at 45 minutes and 10 hours post-dose in young adults with ADHD.
- Trial name
- NCT04027361
- Testing
- Amphetamine Extended Release (ER) Tablet 20 mg
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Tris Pharma, Inc.
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