Clinical trials: Behavioural Disturbances
Disruptive Behaviors
Hybrid Pilot of Personalized Parent-Child Interaction Therapy
The goal of this clinical trial is to learn whether a personalized version of Parent-Child Interaction Therapy (PCIT), called MY PCIT, can improve treatment fit, treatment participation, and outcomes for young children with…
- Trial name
- PCIT (NCT07887295)
- Testing
- Behavioral Parent Training
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Parent-Child Relations, Family Relations
Lausanne Trialogue Paradigm - Brief: A Family Model for Child Mental Health in a Community Setting
The current study is a feasibility pilot of the Lausanne Trialogue Play paradigm Intervention - Brief (LTP-Brief), a family systems therapy implemented in a community mental health setting.
- Conditions
- Parent-Child Relations, Family Relations, Internet-Based Intervention, Mental Health Issue
- Trial name
- LTP-B (NCT05356247)
- Testing
- Lausanne Trialogue Play Brief
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- York University
Behavior Problem, Parenting
Chicago Parent Program for Foster and Kinship Caregivers
The primary objective of this study is to test the effects of an evidence-based prevention intervention (CPP) adapted for foster and kinship caregivers of young children (FC; foster care) on caregiver competence and child…
- Trial name
- NCT06170047
- Testing
- Chicago Parent Program for Foster Care, Usual Care
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Mental Health Issue, Externalizing Behavior Problems
3D-Transition: Challenges and Resources of Children and Their Families During the Transition From Preschool to School
The 3D-Transition study is a follow-up of the 3D Cohort pregnancy study (NCT03113331, which covered from the 1st trimester of pregnancy to age 2 years) as the children transition into kindergarten and first grade.
- Conditions
- Mental Health Issue, Externalizing Behavior Problems, Internalizing Behavior Problems, Cognitive Development
- Trial name
- NCT04873518
- Where
- 3 sites in Canada
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Movement Disorders, Dystonia
Brain Sensing in Neurological and Psychiatric Disorders
High-frequency deep brain stimulation (DBS) is an effective treatment strategy for a variety of movement disorders including Parkinson's disease, dystonia and tremor1-5, as well as for other neurological and psychiatric disorders…
- Conditions
- Movement Disorders, Dystonia, Parkinson Disease, Tremor
- Trial name
- NCT04810325
- Volunteers
- 65 people
- Sponsor
- University College, London
Child Behavior Problem, Intellectual Disability
Determining the Effectiveness of Sexual Health and Development Education for Children With Intellectual Disability
By integrating sexuality and disability literatures, theories, and research, this study aims to: determine the effectiveness of sexual health and development education for children (12-18 years) with mild to moderate intellectual…
- Conditions
- Child Behavior Problem, Intellectual Disability, Sexuality
- Trial name
- NCT04635969
- Testing
- Sexual Health and Development Education for Children With Intellectual Disability
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aylin KURT
Depressive Disorder, Generalized Anxiety Disorder
Qualitative Study of Student Financial Insecurity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Generalized Anxiety Disorder, Suicidal Ideation
- Trial name
- QUALIPEPSY (NCT07719816)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Refractory Epilepsy
Modulation of Emotion Perception in Humans Via Amygdala Stimulation
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have intracranial EEG electrodes.
- Trial name
- NCT05292183
- Testing
- Electrical Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Rett Syndrome
Nutritional Aspects of Rett Syndrome
OBJECTIVES: I. Determine dietary macronutrient intake in children with Rett syndrome and in healthy controls. II. Measure sleeping and awake metabolic rates in various positions, i.e., reclining, sitting, and standing, by…
- Trial name
- NCT00004656
- Testing
- Metabolic assessment with body composition evaluation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Genetic, Diagnostic Strategies
A Study of the Value of Trio Genome Sequencing in the Etiological Evaluation of Early-Onset and/or Atypical Psychiatric Disorders Without Intellectual Disability or Congenital Anomalies
According to the World Health Organization, one in eight people worldwide has a mental disorder, defined as a significant impairment in thinking, emotional regulation, or behavior.
- Trial name
- PSYGEN (NCT07686653)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 255 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Psychiatric Disorders
A Study on Evaluation of Mental Health Index of Patients With Psychiatric Disorders
Psychiatric patients under the mental impaired influences, their living function were disabled, and their social lives were handicapped consequently.
- Trial name
- NCT00166764
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Multiple Sclerosis
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Immune Globulin for Multiple Sclerosis
OBJECTIVES: I. Determine whether high-dose intravenous immune globulin (IVIG) is more effective than placebo in restoring neurologic function (muscle strength) in patients with multiple sclerosis. II.
- Trial name
- NCT00004744
- Testing
- immune globulin
- Volunteers
- 76 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Coping, Stress Disorders, Post-Traumatic
D-Stress Baltimore: School-based Mindfulness Instruction
Effective strategies to ameliorate the negative effects of stressful urban living are greatly needed. D-Stress Baltimore (DSB) is an evidence-based mindfulness-based instructional program of stress-reduction techniques, found to…
- Conditions
- Coping, Stress Disorders, Post-Traumatic, Mental Health Wellness 1
- Trial name
- NCT02493218
- Testing
- Mindfulness Instruction, Health Education
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Bipolar Disorder, Schizophrenia
COMpassion for Psychiatric Disorders And Self-Stigma
People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into…
- Conditions
- Bipolar Disorder, Schizophrenia, Depression, Borderline Personality Disorder
- Trial name
- COMPASS (NCT05698589)
- Testing
- Compassion Focused Therapy, Ending Self Stigma
- Where
- 7 sites in France
- Volunteers
- 336 people
- Sponsor
- University Hospital, Strasbourg, France
Behavior Problem
Tailoring CPP for the Foster Care Setting
The primary objective of this study is to tailor the Chicago Parent Program, an evidence-based parent training program, for the foster care setting and pilot the content in two cohorts of foster and kinship caregivers (Gross et…
- Trial name
- CPP-FC (NCT05856435)
- Testing
- Chicago Parent Program for Foster Care
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Affective Symptoms, Empathy
Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits
The goal of this study is to test a novel intervention for children ages 6-11 with elevated callous-unemotional (CU) traits. Conduct problems are among the most prevalent and costly mental health conditions of childhood, and a…
- Trial name
- NCT04159168
- Testing
- Facial Affect Sensitivity Training (FAST), Implicit Gaze Training task (Active control condition)
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Alabama, Tuscaloosa
Child Behavior Problem, Parenting
Promoting Healthy Families: A Canadian Evaluation
Interventions that promote safe, stable, and nurturing relationships between caregivers and children are key to improving healthy family relationships, reducing child socioemotional and behaviour problems, and preventing child…
- Trial name
- PHF (NCT04702191)
- Testing
- Triple P, Circle of Security Parenting
- Where
- Canada
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- McMaster University
Behavior Problem, Behavior, Child
Effectiveness of an Online Parenting Training
Child and adolescent behavioral health problems are related to the leading causes of youth morbidity and mortality. Parent-focused preventive interventions, such as GenerationPMTO (GenPMTO), effectively prevent behavioral health…
- Conditions
- Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
- Trial name
- NCT05111886
- Testing
- Communication Skills Training, eHealth GenPMTO, Written Referral Process
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota